An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2024 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

16061 entries, 14144 authors and 1947 subjects. Updated: December 10, 2024

Permanent Link for Entry #14669

  • 12437

Ueber die Beziehungen von chemischer Constitution. Vertheilung und pharmakologischer Wirkung: Vortrag, gehalten im Verein für Innere Medicin am 12. December 1898.

circa 1902.

In this speech Ehrlich explained how the molecular structure of a drug can define its action and function. It represents his first attempts at modifying the molecular structure of a compound in order to tailor the in vivo physiological actions of a drug.

Digital facsimile from wellcomelibrary.org at this link. According to Ehrlich's Collected papers, this was reprinted from v., Leyden-Festschr., Berlin: Hirschwald, 1902. That may have been its first publication.

English translation as "The relations existing between chemical constitution, distrtibution and pharmacological action," in Collected papers of Paul Ehrlich (No. 86.4).

(Thanks to Juan Weiss for this reference and its interpretation.)



Subjects: PHARMACOLOGY › Pharmacodynamics
Permalink: historyofmedicine.com/id/14669