An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2024 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

16061 entries, 14144 authors and 1947 subjects. Updated: December 10, 2024

Permanent Link for Entry #15551

  • 13285

Establishment in culture of pluripotential cells from mouse embryos.

Nature, 292, 154-56, 1981.

Evans and Kauffman were the first to identify, isolate and successfully culture embryonic stem cells using mouse blastocysts. This discovery opened the doors to the creation of “murine genetic models” -- mice that have had one or several of their genes deleted or otherwise modified to study their function in disease.

In 2007 Evans shared the Nobel Prize in Physiology or Medicine with Mario R. Capecchi and Oliver Smithies "for their discoveries of principles for introducing specific gene modifications in mice by the use of embryonic stem cells."



Subjects: BIOLOGY › Cell Biology, EMBRYOLOGY, NOBEL PRIZES › Nobel Prize in Physiology or Medicine , Regenerative Medicine
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