An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2024 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

16061 entries, 14144 authors and 1947 subjects. Updated: December 10, 2024

Permanent Link for Entry #16450

  • 14137

Delayed anaphylaxis, angioedema, or urticaria after consumption of red meat in patients with IgE antibodies specific for galactose-alpha-1,3-galactose.

J. Allergy & Clinical Immunology, 123, 426-433, 2009.

Discovery of mammalian meat allergy (MMA) or Alpha-gal syndrome (AGS), also called Alpha-gal allergy, a type of meat allergy characterized by delayed onset of symptoms (3-8 hours) after ingesting mammalian meat. The allergy is a reaction to the carbohydrate galactose-alpha-1,3-galactose ("alpha-gal") in which the body is overloaded with immunoglobulin E (IgE) antibodies on contact with the carbohydrate. Bites from specific tick species, such as the lone star tick (Amblyomma americanum) in the US, and the paralysis tick (Ixodes holocyclus) in Australia have been implicated in the development of this delayed allergic response.

Full text available from PubMedCentral at this link.
Order of authorship in the original publication: Commins, Sharma,....Platts-Mills.

(Thanks to Juan Weiss for this reference and its interpretation.)



Subjects: ALLERGY
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