An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2022 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”
Permanent Link for Entry #9059
On protein synthesis.Symp. Soc. Exp. Biol., 12, 138-63, 1958.
This paper proposed two general principles: 1) The Sequence Hypothesis: “The order of bases in a portion of DNA represents a code for the amino acid sequence of a specific protein. Each ‘word’ in the code would name a specific amino acid. From the two dimensional genetic text, written in DNA, are forced the whole diversity of uniquely shaped three-dimensional proteins” , and 2) The Central Dogma: “Information is transmitted from DNA and RNA to proteins, but information cannot flow from a protein to DNA. This paper “permanently altered the logic of biology” (Judson).
Subjects: BIOLOGY › MOLECULAR BIOLOGY, BIOLOGY › MOLECULAR BIOLOGY › Protein Synthesis