An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2022 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

15961 entries, 13944 authors and 1935 subjects. Updated: April 29, 2024

MOSSO, Angelo

8 entries
  • 12274

Die Diagnostik des Pulses in Bezug auf die localen Veränderungen desselben.

Leipzig: Verlag von Veit, 1879.

Bedford 56: "Pulse reporting by hydrosphygmograph by Italian physiologist Angelo Mosso (1846-1910), who was professor of pharmacology at Turin University." Digital facsimile from the Internet Archive at this link.

Subjects: CARDIOLOGY › CARDIOVASCULAR PHYSIOLOGY › Cardiac Electrophysiology
  • 6838

Sulla circolazione del sangue nel cervello dell’uomo. Ricerche sfigmografiche.

Reale Accademia dei Lincei. Memorie, 3rd series, 5 (1879-80), 1880.

In this work Angelo Mosso reported his discovery that blood circulation in the brain increases in certain discrete areas during mental activity, and published the records of this activity produced by the machine he invented to record these changes. As the first method of imaging brain function, Mosso's work paved the way for modern-day brain imaging techniques such as CT scans, PET scans and magnetic resonance imaging.

“. . . Mosso was the first to experiment with the idea that changes in the flow of blood in the brain might provide a way of assessing brain function during mental activity. Mosso knew that, in newborn children, the fontanelles—the soft areas on a baby’s head where the bones of the skull are not yet fused—can be seen to pulsate with the rhythm of the heartbeat. He noticed similar pulsations in two adults who had suffered head injuries that left them with defects of the skull, and observed, in particular, a sudden increase in the magnitude of those pulsations when the subjects engaged in mental activities” (Kolb & Whishaw, Fundamentals of Human Neuropsychology, 132).

Mosso devised a graphic recorder to document these pulsations, demonstrating that blood pressure changes in the brain caused by mental exertion occur independently of any pressure changes in the rest of the body. Mosso concluded that brain circulation changes selectively in accordance with mental activity, stating that “we must suppose a very delicate adjustment whereby the circulation follows the needs of the cerebral activity. Blood very likely may rush to each region of the cortex according as it is most active” (quoted in Shepherd, Creating Modern Neuroscience, 185). English translation in M. E. Raichle and G. M. Shepherd, Angelo Mosso's Circulation of Blood in the Human Brain (New York: Oxford Univ. Press, 2014.)


Subjects: IMAGING, INSTRUMENTS & TECHNOLOGIES, INSTRUMENTS & TECHNOLOGIES › Medical Instruments, NEUROSCIENCE › NERVOUS SYSTEM › Brain, including Medulla: Cerebrospinal Fluid, NEUROSCIENCE › Neurophysiology
  • 10113

La paura.

Milan: Fratelli Treves, Editori, 1884.

Mosso conducted experiments with special equipment, which he devised to suit the requirements of the studies. He pursued two main lines of research: the analysis of motor functions and the relationship between physiological and psychic phenomena. Translated into English from the fifth edition in Italian by E. Lough and F. Kesow as Fear, London: Longmans..., 1896. Digital facsimile of the 1884 edition from Google Books at this link; of the English translation from the Internet Archive at this link.

Subjects: INSTRUMENTS & TECHNOLOGIES › Medical Instruments, Neurophysiology
  • 636

Les lois de la fatigue étudiées dans les muscles de l’homme.

Arch. ital. Biol., 13, 123-86, 1890.

Mosso invented the ergograph from the study of voluntary contraction. The description of the instrument is on pages 124-41 of the above article.

  • 639

La fatica.

Milan: frat. Treves, 1891.

Mosso investigated muscular fatigue with the ergograph of his invention. He showed fatigue to be due to a toxin produced by muscular contraction. English translation, 1906.

Subjects: BIOCHEMISTRY › Metabolism, INSTRUMENTS & TECHNOLOGIES › Medical Instruments
  • 2801

Sphygmomanomètre pour mésurer la pression du sang chez l’homme.

Arch. ital. Biol., 23, 177-97, 1895.

A sphygmomanometer for registering the blood-pressure in the finger was invented by Mosso.

Subjects: CARDIOLOGY › Tests for Heart & Circulatory Function › Sphygmogram, INSTRUMENTS & TECHNOLOGIES › Medical Instruments › Sphygmomanometer
  • 950

Fisiologia dell’uomo sulle Alpi. Studii fatti sul Monte Rosa.

Milan: frat. Treves, 1897.

Mosso made important investigations on respiration at high altitudes. He considered that the respiratory symptoms produced at high altitudes were due to lack of carbon dioxide. English translation, London, 1898.

Subjects: Altitude or Undersea Physiology & Medicine, RESPIRATION
  • 952

La physiologie de l’apnée étudiée chez l’homme.

Arch. Ital. Biol., 40, 1-30, 19031904.

First studies of the physiology of apnea in man.