An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2022 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

15961 entries, 13944 authors and 1935 subjects. Updated: April 29, 2024

GIBBS, Clarence Joseph, Jr.

2 entries
  • 13914

Attempts to demonstrate a transmissible agent in Kuru, Amyotrophic Lateral Sclerosis, and other subacute and chronic progressive nervous system degenerations in man. Addendum p. 46 in: Slow, latent, and temperate virus infections. NINDB Monograph No. 2. Edited by D. Carleton Gajdusek, Clarence J. Gibbs, Jr., and Michael Alpers.

Washington, DC: U.S. Department of Health, Education, and Welfare, 1965.

In their Addendum on p. 46 the authors stated that 20 and 21 months post innocculation in the brain with brain material from Kuru patients two chimpanzees showed symptoms of an illness suggestive of Kuru. Digital facsimile from Google Books at this link.

The authors formally reported these results the following year in Gajdusek, Gibbs, & Alpers, "Experimental transmission of a Kuru-like syndrome to chimpanzees," Nature, 209 (1966), 794-96.

(Thanks to Juan Weiss for this reference and its interpretation.)

Subjects: INFECTIOUS DISEASE › Prion Diseases, NEUROLOGY › Degenerative Disorders
  • 4729.2

Transmission of two subacute spongiform encephalopathies of man (Kuru and Creutzfeldt–Jakob disease) to New World monkeys.

Nature, 230, 588-91, 1971.

Following Hadlow's suggestion (1959), Gadjusek was able to transmit Kuru and Creutzfeldt–Jakob disease to primates through cerebral inoculations. Similarity in the clinical course of the diseases and in the cellular pathology of brain material suggested similar causative agents.

Gajdusek shared the Nobel Prize with Baruch S. Blumberg in 1976 for his work on infectious diseases.

Subjects: INFECTIOUS DISEASE › Prion Diseases, NEUROLOGY › Degenerative Disorders