An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2024 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

16061 entries, 14144 authors and 1947 subjects. Updated: December 10, 2024

WIMMER, Eckard

1 entries
  • 9176

Primary structure, gene organization and polypeptide expression of poliovirus RNA.

Nature, 291, 547-553, 1981.

The poliovirus genome. With around 10 co-authors. 

"The primary structure of the poliovirus genome has been determined. The RNA molecule is 7,433 nucleotides long, polyadenylated at the 3′ terminus, and covalently linked to a small protein (VPg) at the 5′ terminus. An open reading frame of 2,207 consecutive triplets spans over 89% of the nucleotide sequence and codes for the viral polyprotein NCVPOO. Twelve viral polypeptides have been mapped by amino acid sequence analysis and were found to be proteolytic cleavage products of the polyprotein, cleavages occurring predominantly at Gln-Gly pairs" (Abstract).

 



Subjects: BIOLOGY › MOLECULAR BIOLOGY, BIOLOGY › MOLECULAR BIOLOGY › Genomics, VIROLOGY