An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2024 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

16061 entries, 14144 authors and 1947 subjects. Updated: December 4, 2024

DENG, HongKui

1 entries
  • 11365

Identification of a major co-receptor for primary isolates of HIV-1.

Nature, 381, 661-666, 1996.

Order of authorship in the original publication: Deng, Liu, Ellmeier.... This paper was immediately followed in the same issue of Nature by:

Tatjana Dragic, Virginia Litwin, Graham P. Allaway et al. "HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5," Nature, 381, 667-673.

What was called CC-CKR-5 in the Dragic, Litwin, Allaway paper was later named CCR5. These two papers laid the theory and the foundation behind the purposeful and targeted search for bone marrow donors with this mutation that finally achieved success 13 years later in Gero Hütter et al GM 10775 ("Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation", 2009). 

(Thanks to Juan Weiss for this reference and its interpretation.)



Subjects: INFECTIOUS DISEASE › HIV / AIDS, INFECTIOUS DISEASE › SEXUALLY TRANSMITTED DISEASES