ABEL, John Jacob
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On the pigment of the negro's skin and hair.J. exp. Med., I, 361- 400, 1896."In the present state of our knowledge we can only say that it seems highly probable that the pigment of the negro's hair is not different from the dark pigment found in the hair of the white races, and we may infer that the pigment of the black skin differs only in amount and not in kind from that deposited in the skin of the white man" (p. 400). Digital facsimile from PubMedCentral at this link. Subjects: BLACK PEOPLE & MEDICINE & BIOLOGY, DERMATOLOGY, PHYSIOLOGY |
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On the blood-pressure-raising constituent of the suprarenal capsule.Johns Hopk. Hosp. Bull., 8, 151-57, 1897.Abel and Crawford further investigated the pressor substance of Oliver and Schäfer calling it “epinephrine”. Subjects: Ductless Glands: Internal Secretion › Adrenals |
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Ueber den blutdruckerregenden Bestandtheil der Nebenniere, das Epinephrin.Hoppe-Seyl. Z. physiol. Chem., 28, 318-62, 1899.Subjects: Ductless Glands: Internal Secretion › Adrenals |
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On the poisons of Amanita phalloides.J. biol. Chem., 2, 273-88, 1906 – 1907.Abel and Ford showed that there were two poisons in the fungus Amanita phalloides, and that immunity against them could be attained. A further study on the subject by the same authors is in Arch. exp. Path. Pharmak., 1908, Suppl., 8-15. Subjects: Mycology, Medical, TOXICOLOGY |
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On the pharmacological action of some phthaleins and their derivatives.J. Pharmacol., 1, 231-64, 1909.This work led to the universal clinical use of phenolsulphonephthalein in renal function tests and of phenoltetrachlorphthalein in hepatic function tests. Subjects: NEPHROLOGY › Renal Physiology › Tests for Kidney Function |
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Tetanic convulsions in frogs produced by acid fuchsin, and their relation to the problem of inhibition in the central nervous system.J. Pharmacol., 2, 169-99, 1910.Subjects: NEUROSCIENCE › NERVOUS SYSTEM › Brain, including Medulla: Cerebrospinal Fluid |
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Two crystalline pharmacological agents obtained from the tropical toad Bufo agua.J. Pharmacol., 3, 319-77, 1911 – 1912.Isolation of bufagin. Preliminary communication in J. Amer. med. Assoc., 1911, 56, 1531-35. Subjects: PHARMACOLOGY, TOXICOLOGY |
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On the action of drugs and the function of the anterior lymph hearts in cardiectomized frogs.J. Pharmacol., 3, 581-608, 1913.Abel was one of America’s most distinguished pharmacologists. See A. M. Harvey. "Pharmacology’s giant," Johns Hopk. med. J., 1974, 135, 245-58. Subjects: PHARMACOLOGY, PHYSIOLOGY › Comparative Physiology |
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On the influence of the lymph hearts upon the action of convulsant drugs in cardiectomized frogs. II.J. Pharmacol., 6, 91-122, 1914.Subjects: PHARMACOLOGY, PHYSIOLOGY › Comparative Physiology |
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On the removal of diffusible substances from the circulating blood of living animals by dialysis.J. Pharmacol., 5, 275-316, 1914.Hemodialysis. See also No. 1976. Preliminary communication in Trans Ass. Amer. Phycns., 1913, 28, 51-4. "Together with L.G. Rowntree and B.B. Turner, Abel devised what they called a "vividiffusion" apparatus, consisting of a series of tubes surrounded by fluid. They first demonstrated the apparatus at the Physiological Congress in Groningen in 1914.[9] By allowing arterial blood to enter at one end of the connection, and later return to circulation through the venous connection after dialysis, they were able to demonstrate the existence of free amino acids in blood. By isolating these amino acids from blood circulation, Abel conducted various subsequent researches on the structure of proteins in the blood. Not only did Abel use the apparatus for his research work, he also realized the great clinical potential such dialysis machine would have on managing the damaging effects of renal failure.[10] The vividiffusion apparatus Abel devised is the precursor to the modern day dialysis machine" (Wikipedia article on John Jacob Abel, accessed 08-2017). Subjects: BIOCHEMISTRY, NEPHROLOGY › Renal Disease › Dialysis |
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Plasma removal with return of corpuscles (plasmaphaeresis).J. Pharmacol., 5, 625-41, 1914.Report of a method of removal of plasma from the living animal, with return of the corpuscles after washing and separation by centrifugalization. See the authors' earlier papers in the same journal, 1914, 5, 275-316, 611-23. Subjects: THERAPEUTICS |
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Evaluation of the hormone of the infundibulum of the pituitary gland in terms of histamine, with experiments on the action of repeated injections of the hormone on the blood pressure.J. Pharmacol., 20, 65-84, 1922 – 1923.Subjects: Ductless Glands: Internal Secretion › Pituitary, ENDOCRINOLOGY › Pituitary |
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Further investigations on the oxytocic-pressor-diuretic principle of the infundibular portion of the pituitary gland.J. Pharmocol., 22,289-316, 1923 – 1924.Subjects: Ductless Glands: Internal Secretion › Pituitary |
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Crystalline insulin.Proc. nat. Acad. Sci.(Wash.), 12, 132-36, 1926.Crystalline insulin first obtained. See also J. Pharmacol., 1927, 31, 65-85. Subjects: Ductless Glands: Internal Secretion › Pancreas |