An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2022 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

15858 entries, 13798 authors and 1925 subjects. Updated: February 4, 2023

DELBRÜCK, Max

3 entries
  • 254.1

Ueber die Natur der Genmutation und der Genstruktur.

Nachr. Ges. Wiss. Göttíngen, math.-fis. Kl., Fachgr. 6, 1, 189-245, 1935.

This paper is divided into four sections. The first, by Timofeev-Ressovskij, describes the mutagenic effects of x-rays and gamma rays on Drosophila melanogaster; the second part, by Zimmer, analyzes Timofeev-Ressovskij's results theoretically. The third and most remarkable section, by Delbrück, puts forth a model of genetic mutation based on atomic physics. It represents Delbrück's debut in biology. This has been called the “green paper”, referring to the color of the paper cover of the Nachrichten, and also the Dreimännerarbeit of genetics, for the three authors involved. This paper provided much of the material for Erwin Schrodinger's What is life? (1944), a work that takes a "naive physicist's" approach to the problems of heredity and variation; Shrodinger's book is often cited as having inspired Watson, Crick, Wilkins and others to focus their careers on the problems of molecular biology. Digital facsimile of the 1935 paper from Universität Zurich at this link.

 



Subjects: BIOLOGY › MOLECULAR BIOLOGY, GENETICS / HEREDITY
  • 14005

Electron microscope studies of bacterial viruses.

J. Bacteriol., 46, 57-76, 1943.

This work demonstrated the absorption of the phages on the host cell, and the lysis of the host cell and the liberation of a hundred or so daughter paritcles from each cell. It also showed that the particles multiply inside the cells rather than at their surfaces, since unti lysis occurs the number of particles visible at the surface remains constant. 
Digital facsimile from PubMedCentral at this link. For an extensive commentary on this paper, including correspondence between Anderson and Delbruck before and after publication see T. F. Anderson, "Electronic microscopy of phages," Phage and the origins of molecular biology. Expanded Edition, edited by John Cairns, Gunther Stent and James D. Watson (1992) 63-78.



Subjects: IMAGING › Photography / Photomicrography , VIROLOGY › Bacteriophage
  • 2578.5

Induced mutations in bacterial viruses.

Cold Spring Harbor Symp. quant. Biol., 11, 33-37, 1946.

Genetic recombination in bacteriophages. Delbrück shared the Nobel Prize with A. D. Hershey and S. E. Luria in 1969 for his work on replication mechanisms and genetic structure of viruses.



Subjects: BIOLOGY › MOLECULAR BIOLOGY, VIROLOGY, VIROLOGY › Bacteriophage