An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2022 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

15859 entries, 13798 authors and 1925 subjects. Updated: February 5, 2023

DULBECCO, Renato

6 entries
  • 2526.1

Genetic recombinations leading to production of active bacteriophage from ultraviolet inactivated bacteriophage particles.

Genetics 34, 93-125, 1949.

Luria shared the Nobel Prize in 1969 with M. Delbrück (No. 2578.5) and A. D. Hershey (No. 256) for work on genetics and replication of bacteria.



Subjects: BIOLOGY › MOLECULAR BIOLOGY, GENETICS / HEREDITY, VIROLOGY › Bacteriophage
  • 13999

Production of plaques in monolayer tissue cultures by single particles of an animal virus.

Proc. Nat. Acad. Sci. (USA), 38, 747-752, 1952.

Following Max Delbruck's advice, Dulbecco visited the major centers of animal virus work in the US in order to discover a way to quantitatively assay animal viruses by a plaque technique, similar to the technique that had recently been developed for bacterial viruses (bacteriophages). Within less than a year Dulbecco worked out such a method for Western equine encephalitis virus, which then opened up animal virology to quantitative work. The technique was then used by Dulbecco and Vogt to study the biological properties of poliovirus. Digital facsimile from PubMedCentral at this link.



Subjects: VIROLOGY
  • 14000

Plaque formation and isolation of pure lines with poliomyelitis viruses.

J. Exp. Med., 99, 167-182, 1954.

Dulbecco and Vogt were the first to successfully grow the poliovirus in vitro. They were also able to plaque purify it-- an essential step for subsequent vaccine production.



Subjects: IMMUNOLOGY › Vaccines, VIROLOGY › VIRUSES (by Family) › Picornaviridae › Poliovirus
  • 2660.13

Virus-cell interaction with a tumour-producing virus.

Proc. Nat. Acad. Sci. (Wash.), 46, 365-70, 1960.

Polyomavirus (papovavirus) shown to be capable of transforming cells in culture.  Full text from PubMedCentral at this link.



Subjects: ONCOLOGY & CANCER, VIROLOGY, WOMEN, Publications by › Years 1900 - 1999
  • 13947

The integrated state of viral DNA in SV40-transformed cells.

Proc. Nat. Acad. Sci. (USA), 60, 1288-1295, 1968.

Dulbecco and his group demonstrated that the infection of normal cells with certain types of viruses (oncoviruses) led to the incorporation of virus-derived genes into the host-cell genome, and that this event lead to the transformation (the acquisition of a tumor phenotype) of those cells. Order of authorship in the original publication: Sambrook, Westphal, Srinvasan, Dulbecco. Digital facsimile from PubMedCentral at this link.



Subjects: VIROLOGY › Molecular Virology
  • 2660.27

From the molecular biology of oncogenic DNA viruses to cancer. Les Prix Nobel en 1975, pp. 172-80.

Stockholm: Nobel Foundation, 1975.

Dulbecco shared the Nobel Prize in 1975 with D. Baltimore and H. M. Temin for his discoveries concerning the interaction between tumor viruses and the genetic material of the cell.



Subjects: BIOLOGY › MOLECULAR BIOLOGY, ONCOLOGY & CANCER, VIROLOGY › Molecular Virology