An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to Circa 2020 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

15475 entries, 13329 authors and 1903 subjects. Updated: December 3, 2021

KÜHNE, Wilhelm Friedrich

7 entries
  • 620

Untersuchungen über Bewegungen und Veränderungen der contraktilen Substanz.

Arch. Anat. Physiol, wiss. Med., 564-642, 748-835, 1859.

Proof of the coagulability of muscle proteins.



Subjects: BIOCHEMISTRY
  • 1269

Ueber die peripherischen Endorgane der motorischen Nerven.

Leipzig: Wilhelm Engelmann, 1862.

Kühne described the neuromuscular end organ (“Kühne’s spindle”) and introduced the term “telolemma” for the outer covering of its sheath.



Subjects: NEUROSCIENCE › NERVOUS SYSTEM › Peripheral Nerves / Nerve Impulses
  • 1270

Die Muskelspindeln. Ein Beitrag zur Lehre von der Entwickelung der Muskeln und Nervenfasem.

Virchows Arch. path. Anat., 28, 528-38, 1863.

The best early description of proprioceptive receptors in muscles.



Subjects: NEUROSCIENCE › NERVOUS SYSTEM › Peripheral Nerves / Nerve Impulses
  • 1012

Ueber das Trypsin.

Verh. naturh.-med. Ver. Heidelberg, n.F. 1, 194-98, 18741877.

Isolation of trypsin.



Subjects: GASTROENTEROLOGY › Anatomy & Physiology of Digestion
  • 700.1

Erfahrungen und Bemerkungen über Enzyme und Fermente.

Untersuch. physiol. Inst. Univ. Heidelberg, 1, 291-324, 1878.

Kühne introduced the term “enzyme”.



Subjects: BIOCHEMISTRY, Zymology (Zymurgy) (Fermentation)
  • 1519

Ueber den Sehpurpur.

Untersuch. physiol. Inst. Univ. Heidelberg, 1, 15-103, 1878.

Kühne was Professor of Physiology at Amsterdam and Heidelberg. Among his best work is his investigation of visual purple (rhodopsin) which he was first to extract from the retina. Several other papers by him on the same subject appear in the above volume.



Subjects: OPHTHALMOLOGY › Physiology of Vision
  • 1016

Ueber die nächsten Spaltungsproducte der Eiweisskörper.

Z. Biol., 19, 159-208, 1883.

Kühne and Chittenden isolated and named several new substances during their investigation of the products of digestion. See also the same journal, 1884, 20, 11-51; 1886, 22, 409-58; 1889, 25, 358-67.



Subjects: GASTROENTEROLOGY › Anatomy & Physiology of Digestion