An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2024 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

16061 entries, 14144 authors and 1947 subjects. Updated: December 10, 2024

MAKUNDE, Williams Holmes

1 entries
  • 11193

Macrofilaricidal activity after doxycycline treatment of Wuchereria bancrofti: A double blind randomized placebo-controlled trial.

Lancet, 365, 2116-2121, 2005.

Order of authorship in the original paper: Taylor, Makunde, McGarry.... The authors treated infection by the parasitic worm Wuchereria bancrofti, cause of elephantiasis (lymphatic filariasis), by killing the Wolbachia bacteria inside the worm with the antibiotic doxycycline. Since the worm requires the Wolbachia (a symbiont) to live, killing the Wolbachia bacteria eliminates the worm and cures the disease.

(Thanks to Juan Weiss for this reference and its interpretation.)



Subjects: BACTERIOLOGY › BACTERIA (mostly pathogenic; sometimes indexed only to genus) › Rickettsiales › Wolbachia, INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Lymphatic Filariasis (Elephantiasis), PARASITOLOGY, PARASITOLOGY › Helminths › Parasitic Worms › Filaria, PHARMACOLOGY › PHARMACEUTICALS › Antibiotics, WOMEN, Publications by › Years 2000 -