An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2022 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

15791 entries, 13704 authors and 1919 subjects. Updated: September 13, 2022

TISELIUS, Arne Wilhelm Kaurin

4 entries
  • 12830

The moving boundary method of studying the electrophoresis of proteins. (Nova Acta Reg. Soc. Scient. Upsaliensis, IV, 7, No. 4.)

Uppsala, Sweden: Almqvist & Wiksell, 1930.

Tilesius's doctoral dissertation introduced the laboratory technique of moving-boundary electrophoresis, a technique for separation of chemical compounds by electrophoresis in free solution.

(Thanks to Juan Weiss for this reference and its interpretation.)



Subjects: BIOCHEMISTRY, Laboratory Medicine
  • 12831

A new apparatus for electrophoretic analysis of colloidal mixtures.

Trans. Faraday Soc., 33, 524-531, 1937.

Between 1931 and 1937, with financial support from the Rockefeller Foundation, Tiselius developed his "Tiselius apparatus" for moving boundary electrophoresis. In this paper he demonstrated that electrophoresis separated protein fractions into four bands that he named: 1) albumin, 2) alpha, 3) beta, 4) gamma.

(Thanks to Juan Weiss for this reference and its interpretation.)



Subjects: BIOCHEMISTRY, Laboratory Medicine
  • 12832

Electrophoresis of serum globulin. II- Electrophoretic analysis of normal and immune sera.

Biochemical Journal, 31, 1464-1477, 1937.

Tiselius showed that an antibody that he produced in a rabbit by immunizing it with albumin (ovalbumin) was clearly located in the gamma globulin fraction. He summarized the paper with this statement: "Investigation of a highly potent anti-egg albumin ('ovalbumin') serum from rabbit showed that the antibody function migrated with the gamma globulin fraction only."

Consequences of separation and identification of the antibody were that it could be studied and characterized, could be quantitated, and could be used to identify pathologic conditions in which it was either absent or low.

(Thanks to Juan Weiss for this reference and its interpretation.)



Subjects: BIOCHEMISTRY, IMMUNOLOGY, Laboratory Medicine
  • 2576.8

An electrophoretic study of immune sera and purified antibody preparations.

J. exp. Med., 69, 119-31, 1939.

Antibodies shown to be gamma globulins.



Subjects: IMMUNOLOGY › Immunization