CARLTON, Bruce C.
2 entries
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On the colinearity of gene structure and protein structure.Proc. Nat. Acad. Sci. (USA), 51, 266-272, 1964.Yanofsky and colleagues established that gene sequences and protein sequences are colinear in bacteria. Order of authorship in the original publication: Yanofsky, Carlton, ... Henning. In genetics, coliniarity is a property of the genetic code to preserve the order of codons. Digital facsimile from PubMedCentral at this link. Subjects: BACTERIOLOGY, BIOLOGY › MOLECULAR BIOLOGY › Genetic Code |
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The complete amino acid sequence of the tryptophan synthesase a protein (α Subunit) and its colinear relationship with the genetic map of the gene.Proc. Nat. Acad. Sci. (USA), 57, 296-298, 1967.Yanofsky showed that changes in DNA sequence can produce changes in protein sequence at corresponding positions. His work is considered the best evidence in favor of the one gene-one enzyme hypothesis. Order of authorship in the original publication: Yanofsky, Drapeau, Guest, Carlton. Digital facsimile from PubMedCentral at this link. Subjects: BIOLOGY › MOLECULAR BIOLOGY |