An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2024 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

16061 entries, 14144 authors and 1947 subjects. Updated: December 10, 2024

KYRATSOUS, Christos A.

1 entries
  • 13523

REGN-COV2 antibodies prevent and treat SARS-CoV-2 infection in rhesus macaques and hamsters.

Science, 370, 1110-1115, 2020.

The authors, working at Regeneron, showed that a cocktail of two potent neutralizing monoclonal antibodes reduced virus load in the airways and diminshed viral induced pathological sequelae when given both as a prophylatic and/ or as a therapeutic entity. The cocktail also limited evidence of pneumonia in the lungs. One of the antibodies in the cocktail was specifically tailored to safeguard against mutational virus escape. Order of authorship in the original publication: Baum, Ajithdoss...Kyratsous.

(Thanks to Juan Weiss for this reference and its interpretation.)



Subjects: EPIDEMIOLOGY › Pandemics › COVID-19, INFECTIOUS DISEASE › SARS CoV-2 (Cause of COVID-19), PHARMACOLOGY › PHARMACEUTICALS › Biological Medical Product (Biologic)