AJITHDOSS, Dharani K.
|
REGN-COV2 antibodies prevent and treat SARS-CoV-2 infection in rhesus macaques and hamsters.Science, 370, 1110-1115, 2020.The authors, working at Regeneron, showed that a cocktail of two potent neutralizing monoclonal antibodes reduced virus load in the airways and diminshed viral induced pathological sequelae when given both as a prophylatic and/ or as a therapeutic entity. The cocktail also limited evidence of pneumonia in the lungs. One of the antibodies in the cocktail was specifically tailored to safeguard against mutational virus escape. Order of authorship in the original publication: Baum, Ajithdoss...Kyratsous. Subjects: EPIDEMIOLOGY › Pandemics › COVID-19, INFECTIOUS DISEASE › SARS CoV-2 (Cause of COVID-19), PHARMACOLOGY › PHARMACEUTICALS › Biological Medical Product (Biologic) |