An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2022 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

15858 entries, 13798 authors and 1925 subjects. Updated: February 2, 2023


2 entries
  • 6841

Vaccine against viral hepatitis and process. Serial No. 864,788 filed 10 /8 /[19]69. Patent 3636191 issued 1/ 18/ [19]72.

Washington, DC: U.S. Patent Office, 19691972.

First description of the hepatitis B vaccine, the first cancer vaccine, US patent 3636191A. Millman and Blumberg discovered that the blood of individuals carrying the hepatitis B virus contained particles of the outside coating of the virus. This coating, hepatitis B surface antigen (HBsAg), is not infectious; however, HBsAg can provoke an immune response. To develop a vaccine, Millman and Blumberg invented a method of detaching the coatings from the virus. See B. S. Blumberg, editor, Hepatitis B and the Prevention of Primary Cancer of the Liver. Selected Publications of Baruch S. Blumberg. (2000). See also I. Millman, T. Eisenstein & B. Blumberg, Hepatitis B: The Virus, the Disease, and the Vaccine. (New York: Plenum Press, 1984). 

Subjects: HEPATOLOGY › Diseases of the Liver, IMMUNOLOGY › Immunization, IMMUNOLOGY › Vaccines, INFECTIOUS DISEASE › Hepatitis, LAW and Medicine & the Life Sciences › Medical Patents, VIROLOGY › VIRUSES (by Family) › Hepadnaviridae › Hepatitis B Virus
  • 12321

Australia antigen (a hepatitis-associated antigen). Purification and physical properties.

J. exp. Med., 131, 1190-1199, 1970.

 Purification of the Australia antigen and investigation of its physical properties. (Order of authorship in the original publication: Millman, Loeb, Bayer, Blumberg.)

Subjects: INFECTIOUS DISEASE › Hepatitis, VIROLOGY › VIRUSES (by Family) › Hepadnaviridae › Hepatitis B Virus