GUEST, John Rodney
The complete amino acid sequence of the tryptophan synthesase a protein (α Subunit) and its colinear relationship with the genetic map of the gene.Proc. Nat. Acad. Sci. (USA), 57, 296-298, 1967.
Yanofsky showed that changes in DNA sequence can produce changes in protein sequence at corresponding positions. His work is considered the best evidence in favor of the one gene-one enzyme hypothesis. Order of authorship in the original publication: Yanofsky, Drapeau, Guest, Carlton. Digital facsimile from PubMedCentral at this link.
Subjects: BIOLOGY › MOLECULAR BIOLOGY