Kaelin, William G., Jr.
|
HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing.Science, 292, 464-468, 2001.Kaelin and colleagues identified aspects of the molecular machinery in Von Hippel-Landau disease that regulates the activity of genes in response to varying levels of oxygen. Subjects: NOBEL PRIZES › Nobel Prize in Physiology or Medicine, PHYSIOLOGY › Physiology |