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Garrison-Morton-Norman History of Medicine

KNUDSON, JR., Alfred George (1922 – 2016)

1922 – 2016

1 entries in the GMN corpus.

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1971

#13964

Mutation and cancer: Statistical study of retinoblastoma.

KNUDSON, JR., Alfred George (1922 – 2016)

In this paper Knudson first described his "two-hit hypothesis," also known as the "Knudson hypothesis," which explains the incidence of hereditary cancers, such as retinoblastoma. "Humans inherit two copies of every g…