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Garrison-Morton-Norman History of Medicine

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Browse across eight MeSH (opens in new tab) facets — era, geography, science, specialty, technology, history, culture, and reference. Select one tag per group; counts update across the others. What’s new in facet browse how facets relate to subjects and MeSH.

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Drugs & Technology

1,672 entries match Pharmacology & Therapeutics [D01 / E02]

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1954

#2028.42

History of blood transfusion.

MALUF, Nobel Suydam Rustum (1913 – )

1954

#1947

Purification and some properties of cephalosporin N, a new penicillin.

ABRAHAM, Sir Edward Penley (1913 – 1999) & et al.

With G. G. F. Newton and C. W. Hale.

1954

#2660.7

Cytoactive amino-acid and peptide derivatives. I. Substituted phenylalanines.

BERGEL, Franz (1900 – 1987) STOCK, J. A.

Melphalan (a nitrogen mustard) later used in the chemotherapy of cancer.

1954

#4962.4

The pharmacological properties of 2-methyl-2-m-propyl-1, 3-propanediol dicarbamate (Miltown), a new interneuronal blocking agent.

BERGER, Frank Milan (1913 – 2008)

Introduction of meprobamate, later used for the treatment of anxiety. Miltown was the first widely prescribed psychotropic drug.

1954

#7085

Steroids. LIV.Synthesis of 19-Nov-17α-ethynyltestosterone and 19-Nor-17α-methyltestosterone.

DJERASSI, Carl (1923 – 2015)
DJERASSI, Carl (1923 – 2015) MIRAMONTES CARDÉNAS, Luis Ernesto (1925 – 2004)
ROSENKRANZ, George (1916 – )
ROSENKRANZ, George (1916 – ) SONDHEIMER, Franz (1926 – 1981)

Synthesis of Norethisterone (or norethindrone) (or 19-nor-17α-ethynyltestosterone), the first highly active progestin analog that was effective when taken by mouth. This molecule became part of one of the first succes…

1954

#7981

Ritalin, a new synthetic compound with specific analeptic components.

MEIER, R GROSS, F TRIPOD, J

The authors identified Methylphenidate as a stimulant. It is sold under the trade name Ritalin, and other names.

1954

#11916

First pharmacopeia in man's recorded history.

KRAMER, Samuel Noah (1897 – 1990)

The most ancient testimony concerning the opium poppy found to date was inscribed in cuneiform script on a small white clay tablet at the end of the third millennium BC. This tablet was discovered in 1954 during excav…

1955

#1947.1

Cephalosporin C, a new antibiotic containing sulpher and d-x aminoadipic acid.

ABRAHAM, Sir Edward Penley (1913 – 1999) NEWTON, Guy G. F. (1920 – 1969)

1955 –1956

#1947.2

Amphotericins A and B, antifungal antibiotics produced by a streptomycete.

GOLD, W & et al.

With six co-authors.

1955

#2660.8

Carcinolytic action of antibiotics: puromycin and actinomycin.

FARBER, Sidney (1903 – 1973)
FARBER, Sidney (1903 – 1973)

1955

#2527

Reconstitution of active tobacco mosaic virus from its inactive protein and nucleic acid components.

FRAENKEL-CONRAT, Heinz Ludwig (1910 – 1999)
FRAENKEL-CONRAT, Heinz Ludwig (1910 – 1999) WILLIAMS, Robley Cook (1908 – 1995)

First reconstitution of a virus.

1955 –1970

#6581.2

Bibliographia medica Croatica. Hrvatska medicinska bibliografija. 2 vols.

GRMEK, Mirko Dražen (1924 – 2000)

Croatian medical, pharmaceutical and veterinary bibliography; Dio 1, Sr. I, 1470-1875; Sr. II, 1875-1918.

1955

#8329

Asclepiades, his life and writings: A translation of Cocchi's life of Asclepiades and Gumpert's fragments of Asclepiades, by Robert Montraville Green.

ASCLEPIADES OF BITHYNIA (ἈΣΚΛΗΠΙΆΔΗΣ) (-124 – -40)
ASCLEPIADES OF BITHYNIA (ἈΣΚΛΗΠΙΆΔΗΣ) (-124 – -40) GUMPERT, Christian Gottlieb (1772 – 1832) GREEN, Robert Montraville (1880 – 1955)
COCCHI, Antonio (1695 – 1757)
COCCHI, Antonio (1695 – 1757)

Digital facsimile from the Hathi Trust at this link.

1955

#8873

Textes Grecs inédits relatifs aux plantes.

THOMSON, Margaret H.

Previously unpublished ancient Greek textes on botany, with French translations.

1955

#9593

Noord- en Zuidnederlandse Stedelijke Pharmacopeeën.

DAEMS, Willem Frans (1911 – 1994) VANDEWIELE, Leo J.

1955

#11468

Vancomycin, a new antibiotic. I. Chemical and biologic properties.

MCGUIRE, James Myrlin (1909 – ) MCCORMICK, M. H. PITTENGER, G. E.

Edmund Kornfeld, an organic chemist working at Eli Lilly, first isolated Vancomycin in 1953 from a soil sample collected from the interior jungles of Borneo by a missionary, Rev. William M. Bouw (1918-2006). The organ…

1956 –1960

#86.4

Collected papers of Paul Ehrlich. Compiled and edited by F. Himmelweit. 3 vols.

EHRLICH, Paul (1854 – 1915)
EHRLICH, Paul (1854 – 1915) HIMMELWEIT, Fred (1902 – 1977)

Vol. I: Histology, biochemistry, and pathology, Vol. 2: Immunology and cancer research; Vol. 3: Chemotherapy. Most texts are in German. English translations are also published when available. The set includes new Engl…

1956

#1947.3

Mitomycin, a new antibiotic from streptomyces.

HATA, Toju (1908 – 2004) & et al.

Isolation of mitomycin C, effective in Hodgkin’s disease and lymphoma. With six co-authors.

1956

#2442.2

Clinical trials of diphenyl thiourea compound SU 1906 (Ciba 1509E) in the treatment of leprosy. Progress during the first year.

DAVEY, Thomas Frank (1908 – 1983) CURRIE, Gordon

Introduction of diphenylthiourea (thiambutosine) therapy.

1956

#7238

Botanical exploration of the trans-Mississippi West 1790-1850.

MCKELVEY, Susan Delano (1883 – 1964)

Reprinted with a new introduction and bibliographical supplement by Stephen Dow Beckham, Corvallis, OR: Oregon State University Press, 1991.

1956

#7782

Preliminary communication: Malignant disease in childhood and diagnostic irradiation in-utero.

STEWART, Alice Mary (1906 – 2002)
STEWART, Alice Mary (1906 – 2002) & et al.

Stewart was one of the earliest to study the effect of prenatal X-rays, later replaced by ultrasound. She found that the children of mothers who received these X-rays were almost twice as likely to develop leukemia or…

1956

#8957

Lexique des termes de botanique en latin.

ANDRÉ, Jacques

1957

#1947.4

Production and isolation of a new antibiotic, kanamycin.

UMEZAWA, Hamao & et al.

With nine co-authors.

1957

#3978.3

Pharmacological studies of a new oral hypoglycemic drug.

UNGAR, Georges (1906 – 1977) & et al.

Phenformin, a biguanide formerly used in diabetes. With L. Freedman and S. L. Shapiro. Clinical report on pp. 193-4.

1957

#9272

Medicinal uses of plants by Indian tribes of Nevada. Contributions toward a flora of Nevada. No. 45. Revised edition, with summary of pharmacological research by W. Andrew Archer, Nov. 26, 1957.

TRAIN, Percy ARCHER, William Andrew (1894 – 1973) HEINRICHS, James R.

Digital facsimile from the Internet Archive at this link. (First published in 1941.)

1957

#9726

Drug reactions, enzymes and biochemical genetics.

MOTULKSY, Arno G. (1923 – 2018)

Motulsky clearly stated that inheritance might explain many individual differences in the efficacy of drugs and in the occurence of adverse drug reactions.

1957

#12633

The total synthesis of penicillin V.

SHEEHAN, John Clark (1915 – 1992)
SHEEHAN, John Clark (1915 – 1992) HENERY-LOGAN, Kenneth Robert (1921 – 2006)

Sheehan and Henery-Logan reported the step by step synthesis of penicillin V (phenoxymethylpenicillin) and the cyclization of the beta lactam ring, key to creation of beta-lactam antibiotics. (Thanks to Juan Weiss for…

1957

#14250

3,4-Dihydroxyphenylalanine and 5-Hydroxytryptophan as reserpine rntagonists.

CARLSSON, Arvid (1923 – 2018)
CARLSSON, Arvid (1923 – 2018) LINDQVIST, Margit MAGNUSSON, Tor

Carlsson demonstrated that dopamine was a neurotransmitter in the brain and not just a precursor for norepinephrine. Digital facsimile from nature.com at this link. In 2000 Arvid Carlsson shared the Nobel Prize in Phy…

1958

#1931.6

Enzymatic O-methylation of epinephrine and other catechols.

AXELROD, Julius (1912 – 2004)
AXELROD, Julius (1912 – 2004) TOMCHICK, R.

The authors discovered the enzyme "COMT" or cathecol-O-methyltransferase, and determined that it was crucial in the methylation and inactivation of adrenergic and other catecholamine type neurotransmitters. (Thanks to…

1958

#2660.11

Neuartige Krebs-Chemotherapeutica aus der Gruppe der zyklischen N-Lost-Phosphamidester.

ARNOLD, Herbert & et al.

Cyclophosphamide. With F. Bourseaux and N. Brock.

1958

#4011.1

Experimental ringworm in guinea pigs: oral treatment with griseofulvin.

GENTLES, James Clark (1921 – 1987)
GENTLES, James Clark (1921 – 1987)

Use of griseofulvin in the treatment of ringworm.

1958 –1961

#8744

Catalogue of botanical books in the collection of Rachel McMasters Hunt. 2 vols. in 3.

FULTON, John Farquhar (1899 – 1960) QUINBY, Jane (1901 – 1965) STEVENSON, Allan Henry (1903 – 1970) HUNT, Rachel McMasters Miller (1884 – 1963)

Ostensibly the catalogue of Rachel McMasters Hunt's private collection, which she donated to the Hunt Institute for Botanical Documentation at Carnegie Mellon University, this is much more than a finely printed, luxur…

1958

#9740

Herbals of five centuries. A contribution to medical history and bibliography.

NISSEN, Claus (1901 – 1975)

1958

#12215

Les champignons hallucinogenes du Mexique. Études ethnologiques, taxinomiques, biologiques, physiologiques et chimiques.

WASSON, Robert Gordon (1898 – 1986)
HEIM, Roger (1900 – 1979)
HEIM, Roger (1900 – 1979)

1958

#12971

Influence of light on the hyperbilirubinaemia of infants.

CREMER, Richard J. PERRYMAN, P. W. RICHARDS, D. H.

In 1956 Sister Jean Ward of the Premature Unit of the Rochford General Hospital in Essex, England noted the benefit of phototherapy when she took infants outside because she assumed that fresh air had healing benefits…

1958

#13218

Das Buch der Gifte des Gābir Ibn Hayyān Arabischer Text in Faksimile (Hs. Taymūr [sic] Tibb 393, Kairo), übersetzt und Erläuter von Alfred Siggel. (Akademie der Wissenschaften under der Literature [Mainz], Veröffentlichungen der Orientalischen Kommission, Band XIII).

IBN HAYYAN, Jabir ( – 816) SIGGEL, Alfred (1884 – 1959)

Edition and translation of Jabir's The Book on Poisons and on the Repelling of their Harmful Effects (Kitāb al-Sumūm wa-dafʿ maḍārrihā, Kr. no. 2145).

1959

#2442.3

Diethyl dithiolisophthalate in the treatment of leprosy (ETIP or “Etisul”); a progress report.

DAVEY, Thomas Frank (1908 – 1983) HOGERZEIL, L. M.

Ditophal (Etisul) in leprosy.

1959

#2353.2

Experiments on the antituberculous activity of alpha-ethyl-thioisonicotinamide.

RIST, Noël (1906 – 1990) & et al.

Ethionamide. With F. Grumbach and D. Liberman.

1959

#9727

Moderne problem der humangenetik.

VOGEL, Friedrich Otto (1925 – 2006)

In this paper Vogel coined the term pharmacogenetics, as the study of the role of genetics in drug response.

1959

#11405

The discovery of Dicumarol and its sequels.

LINK, Karl Paul Gerhard (1901 – 1978)

An historical account of the discovery of the anticoagulant Warfarin by the primary investigator. The first use for this substance was rat poison. Digital facsimile from ahajournals.org at this link.

1959

#12603

The baths of Pozzuoli. A study of the medieval illuminations of Peter of Eboli's poem

KAUFFMANN, Claus Michael (1931 – ) PETER OF EBOLI, (Petrus de Ebulo) ( – 1220)

1960

#1931.3

The psychosedative properties of methaminodiazepoxide.

RANDALL, Lowell Orlando (1910 – 2005) & et al.

Librium. With four co-authors.

1960

#13632

Bibliographie des Kaffe, des Kakao der Schokolade, des Tee und deren Surrogate bis zum Jahre 1900.

MUELLER, Wolf

1960

#13748

The use of LSD in psychotherapy: Transactions of a conference of D-Lysergic Acid Diethymlamide (LSD-25), April 22, 23 and 24, 1959, Princeton, N. J. Edited by Harold A. Abramson.

ABRAMSON, Harold Alexander (1899 – 1980)

1961

#2353.3

A new synthetic compound with antituberculous activity in mice; ethambutol (dextro-2, 2’-(ethylenediimino)-di-l-butanol).

THOMAS, J. P. & et al.

Ethambutol for the treatment of tuberculosis. With C. O. Baughn, R. G. Wilkinson and R. G. Shepherd.

1961

#10854

The ethnobotany of pre-Columbian Peru.

ASHLEY-TOWLE, Margaret Elizabeth (1902 – 1985)

"....based on analysis of 2200 wild and cultivated plant specimens with clearly defined archaeological contexts... Part I is a systematic ethnobotany with pertinent citations of the botanical and archaeological litera…

1961

#10949

Japanese botany during the period of wood-block printing.

BARTLETT, Harley Harris (1886 – 1960) SHOHARA, Hide

I. An essay on the development of natural history, especially botany, in Japan; on the influence of early Chinese & Western contacts; on Japanese books & wood-block illustration. II. An exhibition of Japanese books & …

1961

#11420

America's pre-pharmacopeial literature.

COWEN, David L. (1909 – 2006)

1961

#12413

The toadstool millionaires.

YOUNG, James Harvey (1915 – 2006)

Chronicles the rise of the patent medicine trade from its beginnings in colonial America until passage of the first federal food and drug law. Digital text available from quackwatch.org at this link.

1962

#2068.2

History of pharmacy in Britain.

MATTHEWS, Leslie Gerald (1897 – 1997)