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1 entries match Diabetes [C19.246] · Diagnostics & Imaging [E01] · Physics, Math & Biomechanics [K01.900.400]
1979
#13980
Expression in Escherichia coli of chemically synthesized genes for human insulin (plasmid construction / lac operon / fused proteins / radioimmunoassay / peptide purification).
GOEDDEL, David V. (1951 – ) KLEID, Dennis G. CREA, Roberto BOLÍVAR ZAPATA, Francisco Gonzalo (1948 – ) & et al.
Working at Genentech, Kleid and Goeddel and colleagues were the first scientists to apply genetic engineering techniques, incorporating chemically synthesized DNA encoding human insulin into E. coli, that expressed, a…