Dalton, Professor of Physiology at the universities of Buffalo and Vermont, and the College of Physicians and Surgeons, New York, was the first American to devote his time exclusively to that subject. He was present at the first demonstration of ether as an anaesthetic, Oct 16,1846, and was quick to see its possibilities as a means of illustrating his lectures with experiments on living animals. As a result of the opposition to vivisection he published the above book. Digital facsimile from Google Books at this link.