“Brown-Séquard’s paralysis”. Lesion of one lateral half of the spinal cord causes paralysis of motion on one side and of sensation on the other. See also the writer’s later paper on pp. 70-73 of the same volume.

By applying a galvanic current to the superior part of the divided sympathetic nerve and causing vascular contraction and a fall in temperature, Brown-Séquard inferred that section of the sympathetic paralysed and dilated the blood-vessels (pp. 489-90). See also Nos. 1325-26.

Brown-Séquard found that excision of both adrenals in animals invariably proved fatal, thus determining their indispensability. He also believed that they had an antitoxic influence upon the blood. His experimental work was of great importance in the development of our knowledge of the internal secretions.

Experimental epilepsy (section of sciatic nerve). See also Arch. Physiol. norm. path., 1869, 2, 211-20, 422-38, 496-503; 1870, 3, 153-60.

Among Brown-Séquard’s best work was his study of the pathways of conduction in the spinal cord.

Brown-Séquard injected into himself a testicular extract in order to bring about rejuvenation. He reported much benefit but his advocacy of this method evoked scepticism and criticism, although it stimulated research on internal secretion, being perhaps the first employment of “male sex hormone”. Further papers on this subject were published by Brown-Séquard in the same journal, 1889, 5 sér., 1, 739-46; 1890, 2, 201-08, 443-57, 641-48; and 1891, 3, 747-61.