An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2024 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

16061 entries, 14144 authors and 1947 subjects. Updated: December 10, 2024

BRENT, Leslie Baruch

4 entries
  • 2578.11

‘Actively acquired tolerance’ of foreign cells.

Nature (Lond.), 172, 603- 06, 1953.

Proof of Burnet and Fenner’s theory of immunity. For their discovery of acquired immunological tolerance Medawar and Burnet (No. 2578.7) shared the Nobel Prize in 1960.



Subjects: IMMUNOLOGY › Immunization
  • 2578.12

Quantitative studies on tissue transplantation immunity. I. The survival times of skin homografts exchanged between members of different inbred strains of mice. II. The origin, strength and duration of actively and adoptively acquired immunity.

Proc. roy. Soc. B, 143, 43-80, 1954.

Experimental production of immunological tolerance by Billingham and colleagues.Paper II distinguished adoptive from passive immunization. E. M. Sparrow was a co-author of paper I.



Subjects: IMMUNOLOGY › Immunization, TRANSPLANTATION, TRANSPLANTATION › Skin Grafting
  • 13526

Quantitative studies of tissue transplantation immunity. IV. Induction of tolerance in newborn mice and studies on the phenomenon of Runt Disease.

Phil. Trans. B., 242, 439-477, 1959.

First description of what became known as Graft-versus-host disease (GvDH). This the authors initially called "graft against host (GAH)." The authors cited three conditions, later known as the Billingham criteria, which must be met for GvHD to occur:

  • 'An immuno-competent graft is administered, with viable and functional immune cells.
  • The recipient is immunologically different from the donor – histo-incompatible.
  • The recipient is immunocompromised and therefore cannot destroy or inactivate the transplanted cells." (Wikipedia article on Graft-versus-host-disease, accessed 8-2021).
(Thanks to Juan Weiss for this reference and its interpretation.)


Subjects: IMMUNOLOGY, TRANSPLANTATION
  • 12794

A history of transplantation immunology.

London & New York: Academic Press, 1996.

Written by one of the founders of the science.



Subjects: IMMUNOLOGY › History of Immunology, TRANSPLANTATION › History of Transplantation