An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2022 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

16011 entries, 14068 authors and 1941 subjects. Updated: June 22, 2024

HAUER, Michael

1 entries
  • 11844

A programmable dual RNA-guided DNA endonuclease in adaptive bacterial immunity.

Science, 337, 816-821, 2012.

Order of authorship in the original publication: Jinek, Chylinski, Fonfar, Hauer, Doudna, Charpentier. Doudna, Charpentier and colleagues showed for the first time that the CRISPR evolutionary immune tool of bacteria against bacteriophages could be manipulated, reprogrammed, and guided to make very specific "cuts" on desired target segments of DNA in the lab, making this a gene-targeting and genome-editing tool. This potentially allowed scientists to change or rewrite the genetic code of any organism at will. However, at this point the science was only applied to bacteria. Digital facsimile from PubMedCentral at this link.

In 2020 Charpentier and Doudna were awarded the Nobel Prize in Chemistry “for the development of a method for genome editing.”

See also Nos. 11845, 11867 and 11849.

 (Thanks to Juan Weiss for this reference and its interpretation.)



Subjects: BIOLOGY › MOLECULAR BIOLOGY › CRISPR , NOBEL PRIZES › Nobel Prize in Chemistry, WOMEN, Publications by › Years 2000 -