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Garrison-Morton-Norman History of Medicine

FERGUSON, Kenneth M.

1 entries in the GMN corpus.

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1978

#14144

Reconstitution of hormone-sensitive adenylate cyclase activity with resolved components of the enzyme.

GILMAN, Alfred Goodman (1941 – 2015)
GILMAN, Alfred Goodman (1941 – 2015) ROSS, Elliot M. HOWLETT, Allyn C. FERGUSON, Kenneth M.

Gilman and colleagues showed that G proteins are in the cell membrane and are stimulated once a ligand (adrenaline) binds the adrenergic receptor. This system can then activate adenyl cyclase to form cyclic AMP. Digit…