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1,008 entries match Immunology & Dermatology [C19 / C20 / C17]
1912
#4148
Precancerous dermatosis. A study of two cases of chronic atypical epithelial proliferation.
Bowen, a Boston dermatologist, first described a precancerous dermatosis (“Bowen’s disease”), which is now considered to be a variant of an intra-epidermal basal cell epithelioma.
1913
#2600.5
The anaphylactic reaction of plain muscle in the guinea-pig.
See No. 2600.2. Dale concluded that histamine induced hypersensitivity reactions.
1913
#3192.1
A biological classification of pneumococci by means of immunity reactions.
Dochez and Gillespie differentiated four types of pneumococci.
1913
#3795
Die Erkrankungen der Blutdrüsen
First attempt to systematize the endocrine disorders. English translation, 1915.
1913
#3899
Infantilism hypophysaire.
Classic account of pituitary infantilism.
1913
#3900
Z kazuistyki zmian anatomo-patholigicznych w przysadce mózgowej
Glinski preceded Simmonds in this important description of post-partum necrosis of the anterior pituitary. Abstract in Dtsch med. Wschr., 1913, 39, 473.
1913
#5066
Die Diphtherietoxin – Hautreaktion des Menschen als Vorprobe der prophylaktischen Diphtherieheilseruminjektion.
Schick developed his test for use as an indication as to whether or not prophylactic injections of antitoxin are necessary in children already exposed to diphtheria. English translation in J. Mt. Sinai Hosp., 1938, 5,…
1913
#5067
Ueber ein neues Diphtherieschutzmittel.
Toxin–antitoxin for immunization against diphtheria.
1914
#2568
Infection and resistance.
1914
#3847
The pathogenesis of experimentally produced goitre.
1914
#3901
Ueber Hypophysisschwund mit tödlichem Ausgang.
“Simmonds’s disease”-pituitary cachexia. See also Virchows Arch. path. Anat., 1914, 217, 226-39.
1914
#5068
Active immunization in diphtheria and treatment by toxin-antitoxin.
With A. Zingher and M. H. Serota. Park was an early advocate of diphtheria immunization with toxin-antitoxin. A second paper is in the same journal, 1915, 65, 2216-20.
1914
#5301
Sobre o tratemento de leishmaniose tegumentar.
Vianna introduced tartar emetic in the treatment of S. American leishmaniasis. His preliminary announcement on this form of treatment was made to the Brazilian Dermatological Society and appears in Arch. brasil. Med.,…
1914
#5325
Zurt Aetiologie und Klinik der Bisskrankheit.
Isolation of Streptothrix (Actinomyces) muris ratti from human patients bitten by rats.
1914
#5536
Les grains botryomycotiques. Leur signification en pathologie et en biologie générales.
Thèse de Paris, No. 267, 1914. Magrou showed botriomycosis (granuloma pyogenicum) to be due to a staphylococcus.
1915
#1124
Bodily changes in pain, hunger, fear, and rage. An account of recent researches into the function of emotional excitement.
Observation of the effect of strong emotions on gastrointestinal motility (No. 1029) led Cannon to examination of the sympathetic nervous system and its emergency function. Cannon showed the close connexion between th…
1915
#1133
The isolation in crystalline form of the compound containing iodine, which occurs in the thyroid; its chemical nature and physiologic activity.
Kendall isolated in crystalline form the thyroid hormone “thyroxine” on Christmas Day, 1914.
1915
#1162.1
A contribution to the physiology of lactation.
Gaines demonstrated the action of the pituitary in lactation.
1915
#2569
The influence of the x-ray on the production of antibodies.
Proof that x rays suppress the antibody response.
1915
#2571
An investigation on the nature of ultra-microscopic viruses.
Twort discovered discovered bacteriophages, a type of virus that attacks bacteria (the term bacteriophage was coined by Félix d’Herelle, who in 1917 independently confirmed Twort’s discovery). The discovery of bacteri…
1915
#3848
Experimental hyperthyroidism.
First successful experimental production of exophthalmic goitre. With C. A. L. Binger and R. Fitz.
1915
#5430.1
Pure cultivation in vivo of vaccine virus free from bacteria.
Noguchi obtained a pure culture of vaccinia virus.
1915
#11015
A study of prolonged fasting.
Study of a subject who was allowed to drink water but ingested no food for 31 days. Digital facsimile from the Internet Archive at this link.
1915
#11753
Outline of common skin diseases including eruptive fevers. Also diet plans for children in use in the Department of Pediatrics, the Johns Hopkins Hospital.
Gilchrist was the first professor to concentrate on dermatology at Johns Hopkins, joining the faculty in 1898. His guide to the common skin diseases, published for the use of medical students at Hopkins, was printed l…
1916
#1033
The control of hunger in health and disease.
Digital facsimile from the Internet Archive at this link.
1916
#2600.6
Human sensitization.
The concept of atopy had its origin in the report by Cooke and Vander Veer in 1916.
1916
#2642
Further investigations on the origin of tumours in mice. III. On the part played by internal secretion in the spontaneous development of tumours.
Demonstration of the influence of an internal secretion on the development of spontaneous cancer. Castration of female mice of a strain in which mammary cancer was frequent reduced its incidence and delayed its growth.
1916
#2570
Further experimental studies on the inheritance of susceptibility to a transplantable tumour, carcinoma (J. W. A.) of the Japanese waltzing mouse.
Marks the beginning of the study of histocompatibility antigens.
1916
#3902
Nanosomia pituitaria
Erdheim made important studies on the pathology of the pituitary. He gave the name “nanosomia pituitaria” to describe pituitary dwarfism. See also his paper in Ergebn. allg. Path, 1926, 21, 482.
1917
#1182
The existence of a typical oestrus cycle in the guinea-pig; with a study of its histological and physiological changes.
The vaginal smear test for estrus; it demonstrates the histological changes occurring in the vagina during the menstrual cycle.
1917
#2601
Anaphylaxie et antianaphylaxie.
English translation, 1919.
1917
#3921.1
Galaktosurie nach Milchzuckergabe bei angeborenen, familiärem, chronischem Leberleiden.
First clear account of galactosemia (although A. von. Reuss may have been describing a case in Wien. med. Wschr., 1908, 58, 799).
1917
#4149
Étude sur le lupus pernio et ses rapports avec les sarcoïdes et la tuberculose.
“Besnier–Boeck–Schaumann disease” (see also Nos. 4095, 4128). Through Schaumann’s paper the systemic nature of sarcoidosis came to be recognized.
1918
#3849
Das Myxödemherz
First systematic study of the characteristic changes of the heart in myxedema.
1919
#1477
Ueber eine nach innen gerichtete Schützfunktion der Haut (Esophylaxie) nebst Bemerkungen über die Entstehung der Paralyse.
Hoffmann stressed the role of the skin as a secretory organ, producing hormone-like substances; he suggested the term “esophylaxis” for this function.
1919
#2440
On the value of a skin reaction to a suspension of leprous nodules.
Mitsuda (lepromin) reaction. English translation by the author in Int. J. Leprosy, 1953, 21, 347-58.
1919
#3849.1
Some considerations on the operation for exophthalmic goitre.
Dunhill’s operation of exophthalmic goitre is described above. He was a pioneer in thyroid surgery.
1919 –1920
#3850
Epinephrin hypersensitiveness test in the diagnosis of hyperthyroidism.
Goetsch devised a skin reaction test for use in the diagnosis of hyperthyroidism
1919
#3922
A system of blood analysis.
Folin–Wu test for blood sugar.
1920
#2645
Squamous-cell epithelioma of the lip. A study of five hundred and thirty-seven cases.
Broders’s classification of tumors, an index of malignancy.
1920
#3796
Verjüngung durch experimentelle Neubelebung der alternden Pubertätsdrüse
Steinach rejuvenation operation, ligation of the vas deferens, later discredited.
1921
#1163
The effect of the anterior lobe administered intraperitoneally upon growth, maturity and oestrus cycles of the rat.
Evans and Long discovered the growth hormone of the anterior pituitary, showing that continued injections of an anterior pituitary extract produced an acceleration in the growth-rate of laboratory animals.
1921 –1922
#1205
The internal secretion of the pancreas.
This paper reports the isolation of insulin. An extract from the pancreas of a dog, removed after ligation of the excretory duct, was found to exercise a reducing influence on the percentage of sugar in the blood. Dig…
1921
#2601.1
Studien über die Ueberempfindlichkeit.
Prausnitz–Küstner reaction. These workers demonstrated antibodies in the blood of persons suffering from atopic allergic diseases. They produced local passive sensitization by intracutaneous injection of serum from a …
1921
#3870
La virilisme pilaire et son association à l’insuffisance glycolytique (Diabète des femmes à barbe).
“Achard–Thiers syndrome”. These writers established as a definite syndrome the combination of hirsutism with diabetes.
1921
#10196
Le bactériophage: Son rôle dans l'immunité.
D'Hérrelle cited several actual reports of successful treatment of bacterial infections by the injection of bacteriophages in animals and humans. These may be considered early attempts at direct gene transfer in vivo …
1922 –1939
#83
Œuvres de Pasteur, réunies par Pasteur Vallery-Radot. 7 vols.
One of the founders of bacteriology, Pasteur's work on fermentation, the doctrine of spontaneous generation (which he exploded), virus diseases and preventive vaccinations, was fundamental. Digital facsimile of the co…
1922 –1923
#1164
Evaluation of the hormone of the infundibulum of the pituitary gland in terms of histamine, with experiments on the action of repeated injections of the hormone on the blood pressure.
1922
#3197.2
Klinische und experimentelle Beitrag zur krampflösenden Wirkung der Purinderivate.
Hirsch established the value of theophylline in the management of asthma.
1922 –1924
#3798