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1,008 entries match Immunology & Dermatology [C19 / C20 / C17]

1922

#3871

Crises solaires et hypertension paroxystique en rapport avec une tumeur surrénale.

First full description of chromaffin cell tumors of the adrenal medulla. With J. Tinel and E. Doumer.

1922

#4150

A new eruptive fever associated with stomatitis and ophthalmia; report of two cases in children.

“Stevens-Johnson syndrome”, a generalized eruption, continued fever, inflamed buccal mucosa, and severe purulent conjunctivitis. B.A. Thomas (Brit. med. J., 1950, 1, 1393) believes this to be merely a severe form of H…

1922

#6609.1

Wunder, Wundgeburt und Wundergestalt in Einblattdrucken des 15-18. Jahrhunderts.

History of teratology in art from 15th to 18th centuries.

1922 –1933

#57

Paracelsus: Sämtliche Werke…Herausg. von K. Sudhoff und W. Mathiessen. 14 vols.

Paracelsus was first to write on miners’ diseases, the first to establish the relationship between cretinism and endemic goitre and to note the geographic differences in diseases. Sudhoff was the author of what remain…

1923

#1134

The acetonitril test for thyroid and of some alterations of metabolism.

The acetonitril test was introduced by Hunt in 1905 (J. biol. Chem., 1, 33) and later modified by him. It shows the activity of thyroid preparations to be proportional to their iodine content.

1923

#1135

An elementary chemical study of the parathyroid glands of cattle.

Hanson isolated the first really potent parathyroid extract.

1923 –1924

#1165

Further investigations on the oxytocic-pressor-diuretic principle of the infundibular portion of the pituitary gland.

1923

#1183

An ovarian hormone.

Isolation of the active principle of the ovarian hormone (oestrin). More detailed account in J. biol. Chem., 1924, 61, 711-23.

1923 –1924

#2573.2

The soluble specific substance of pneumococcus.

Heidelberger, Avery, and their colleagues made a chemical study of the antigenic constituents of the pneumococcus, separating the polysaccharide antigens.

1923

#3797

Greffes testiculaires

Voronoff first reported his controversial experimental rejuvenation by means of testicular transplants in 1919.

1923

#7407

The elephant man and other reminiscences.

The story of Treves's patient, Joseph Carey Merrick (1862-1890), incorrected identified by Treves in these reminiscences as "John Merrick." The story was retold in The elephant man, Bernard Pomerance's 1977 play about…

1924

#562

Das reticulo-endotheliale System.

In an earlier paper on this subject (Münch, med. Wschr., 1922, 69, 1352-56) Aschoff introduced the term “reticulo-endothelial system”; as early as 1914 he grouped certain phagocytic cells into his system.

1924

#1036

Basal metabolism in health and disease.

1924

#1184

The induction of a sexually mature condition in immature females by injection of the ovarian follicular hormone.

Test for recognition of the estrus hormone.

1924

#1238

A description of the glomerular circulation in the frog’s kidney and observations concerning the action of adrenalin and various other substances upon it.

Richards made many experiments concerning the secretion of urine. Among other things he collected and analysed the fluid from a single glomerulus; his work confirmed the theories of Ludwig and Cushny.

1924

#2602

Vascular reactions of the skin to injury. II. The liberation of a histamine-like substance in injured skin; the underlying cause of factitious urticaria and of wheals produced by burning; and observations upon the nervous control of certain skin reactions.

Lewis postulated that a histamine-like substance (“H-substance”) was responsible for the anaphylaxis symptom-complex. See also The blood-vessels of the human skin and their responses, 1927 (No. 797).

1924

#2343

Essai d’immunisation contre l’infection tuberculeuse.

B.C.G. (Bacille Calmette–Guérin) vaccine was first produced in 1906 and subcultured for 13 years. It was first used as a prophylactic against tuberculosis in children in 1921. It remains in use. See also No. 2346.

1924

#2573.1

The genetics of tissue transplantation in mammals.

Little established that the homograft reaction was due to genetic differences between donor and recipient.

1924

#3851

The value of iodine in exophthalmic goitre.

Plummer and Boothby recommended the pre-operative administration of iodine in exophthalmic goitre.

1924

#5069

Ueber cutane Hautreaktion mittels Diphtherie-Toxin zum Nachweis der Diphtherie-Immunität.

The “scratch test”, a cutaneous reaction for determination of susceptibility to diphtheria.

1924

#5083

A scarlet fever antitoxin.

Following their successful attempts to establish individual susceptibility to scarlet fever, these workers prepared an antitoxin for immunization.

1924

#5084

The significance of Streptococcus hemolyticus in scarlet fever and the preparation of a specific anti-scarlatinal serum by immunization of the horse to Streptococcus hemolyticus-scarlatinae.

Dochez and Sherman immunized a horse by repeated injections of scarlet fever toxin. A serum obtained from the horse blanched a scarlet fever rash and, when injected subcutaneously, caused marked amelioration of the ea…

1925

#1136

The extraction of a parathyroid hormone which will prevent or control parathyroid tetany and which regulates the level of blood calcium.

Isolation of parathormone, the active principle of the parathyroids. Collip’s “parathormone”. He showed that it raises the calcium level in para-thyroidectomized dogs.

1925

#2603

Allergic diseases; diagnosis and treatment of bronchial asthma, hay fever, and other allergic diseases.

In his important studies of asthma, Storm van Leeuwen demonstrated that in the great majority of patients allergens are the cause of the condition and also that patients are sensitive to mold spores. He experimented w…

1925

#2649

The melanomata, their morphology and histogenesis. A study of cell origins and transformations, with a critical discussion on aspects of tumour growth, and a clinical review.

The first exhaustive monograph on the pathology of melanoma. Also issued as a separate monograph (Edinburgh: Oliver & Boyd, 1925).

1925

#3862

A case of tetany treated with parathyrin.

First use of parathyroid hormone in the treatment of tetany.

1925

#2574

Immunisation locale; pansements spécifiques.

Besredka’s vaccine, sensitized vaccine. English translation, Baltimore, 1927.

1925

#2575

The chemical aspects of immunity.

1925

#3863

Therapeutischer Versuch bei Ostitis fibrosa generalisata mittels Exstirpation eines Epithelkörperchentumors.

Mandl was the first successfully to treat generalized osteitis fibrosa by extirpation of a parathyroid tumor.

1925

#3872

A case of virilism associated with a suprarenal tumour: recovery after its removal.

Records the first removal (by P. Sargent) of an adrenal cortical tumor. This was followed by disappearance of the heterosexual symptoms, thus establishing the relationship of sexual abnormality and adrenal tumors.

1925

#4150.1

Erythro- et keratodermia variabilis in a mother and daughter.

“Mendes Da Costa’s syndrome” – erythrokeratoderma variabilis.

1925

#4151

A case of relapsing non-suppurative nodular panniculitis, showing phagocytosis of subcutaneous fat-cells by macrophages.

Weber–Christian disease (see No. 4152).

1926

#1137

Chemistry of thyroxine I.

Harington showed that thyroxine is a derivative of tyrosine, and he gave its formula as C15H11O4NI4.

1926

#3785

Der Morbus Gaucher und die ihm ähnlichen Erkrankungen. (Die lipoidzellige Splenohepatomegalie Typus Niemann und die diabetische Lipoidzellenhyperplasie der Milz.)

“Niemann-Pick disease” – a group of inherited, severe metabolic disorders, first noted by Albert Niemann in 1914, (No. 3784) in 1914. Pick’s account is of greater importance.

1926

#1206

Crystalline insulin.

Crystalline insulin first obtained. See also J. Pharmacol., 1927, 31, 65-85.

1926

#4151.1

Über Myome, ausgehend von der quergestreiften willkürlichen Muskulatur.

“Abrikosov’s tumor”, granular-cell myoblastoma.

1926

#4151.2

An unusual type of pemphigus, combining features of lupus erythematosus.

Pemphigus erythematodes. “Senear–Usher syndrome”.

1926

#5289

Essai de prophylaxie des trypanosomiases par des dérivés phénylarsiniques administré

First attempt to induce prophylaxis by chemical means in trypanosomiasis. With S. Nicolau and I. Galloway.

1926

#14313

Studies in intracranial physiology & surgery. The third circulation. The hypophysis. The gliomas. The Cameron Prize Lectures delivered at the University of Edinburgh October 19, 20, 22, 1925.

This series of three lectures was an analytical review by Cushing of the three main categories of scientific work that he had accomplished during the previous 25 years. Remarkably, Cushing completed this review and de…

1927

#797

The blood-vessels of the human skin and their responses.

1927

#1138

Chemistry of thyroxine. III. Constitution and synthesis of thyroxine.

Synthesis of thyroxine.

1927

#1148

Further studies on adrenal insufficiency in dogs.

Cortical hormone first obtained.

1927

#1166

The induction of precocious sexual maturity by pituitary homeotransplants.

Smith was able to induce precocious sexual maturity in mice and rats by the implantation of pituitary tissue.

1927

#1167

Experimental evidence regarding the rôle of the anterior pituitary in the development and regulation of the genital system.

Pituitary tissue implanted in the immature mouse was found by these writers to cause precocious sexual maturity. Thus they showed that the activity of the gonads is maintained by the anterior lobe of the pituitary.

1927

#1168

Das Hormon des Hypophysenvorderlappens.

Isolation of the gonadotrophic hormone of the anterior pituitary (Prolan A & B).

1927

#1185

The menstrual cycle of the monkey, Macacus rhesus. Observations on normal animals, the effects of removal of the ovaries and the effects of injection of ovarian and placental extracts into the spayed animals.

This paper marks the beginning of modern knowledge of the menstrual cycle. Allen showed that uterine bleeding occurs as a withdrawal effect when estrogen ceases to act on the endometrium.

1927

#1186

Über das Vorkommen weiblichen Sexualhormons (Menformon) im Harn von Männern.

Discovery of the estrogenic activity of male urine. With E. Dingemanse, P. C. Hart, and S. E. de Jongh.

1927

#1187

The effect of the injection of a lipoid fraction of bull testicle in capons.

McGee prepared the first active male hormone extract from the lipoid fraction of bull testes. His paper includes a preliminary account of the capon-comb test. See No. 1191.

1927

#2008

Discordance des effets des rayons X, d’une part dans la peau, d’autre part dans le testicule, par le fractionnement de la dose: diminution de l’efficacité dans la peau, maintien de l’efficacité dans le testicule.

Dose fractionation.

1927

#2346

Sur la vaccination préventive des enfants nouveau-nés contre la tuberculose par le B.C.G.