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Garrison-Morton-Norman History of Medicine

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1,008 entries match Immunology & Dermatology [C19 / C20 / C17]

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1937

#12832

Electrophoresis of serum globulin. II- Electrophoretic analysis of normal and immune sera.

TISELIUS, Arne Wilhelm Kaurin (1902 – 1971)
TISELIUS, Arne Wilhelm Kaurin (1902 – 1971)

Tiselius showed that an antibody that he produced in a rabbit by immunizing it with albumin (ovalbumin) was clearly located in the gamma globulin fraction. He summarized the paper with this statement: "Investigation o…

1938

#2576.7

Recherches sur le phénomène de Twort-d’Hérelle (bactériophage ou autolyse hérédo-contagieuse).

WOLLMAN, Eugène (1883 – 1943)
WOLLMAN, Elisabeth (1888 – 1943)
WOLLMAN, Elisabeth (1888 – 1943)

The Wollmans made important contributions to the knowledge on bacteriophage and lysogeny.

1938

#3787.1

Hemolysins as the cause of clinical and experimental hemolytic anemias.

DAMESHEK, William (1900 – 1969) SCHWARTS, Steven Otto (1911 – )

Acquired hemolytic anemia was the first condition to be recognized as an auto-immune disease.

1938

#3799

The oestrogenic activity of certain synthetic compounds.

DODDS, Sir Edward Charles (1899 – 1973)
ROBINSON, Sir Robert (1886 – 1975)
ROBINSON, Sir Robert (1886 – 1975) & et al.

Introduction of stilboestrol, the first synthetic estrogen. With L. Gol[d]berg, W. Lawson,

1938

#3800

Oestrogenic activity of alkylated stilboestrols.

DODDS, Sir Edward Charles (1899 – 1973)
ROBINSON, Sir Robert (1886 – 1975)
ROBINSON, Sir Robert (1886 – 1975)

Introduction of dienoestrol. With L. Gol[d]berg, W. Lawson.

1938

#3801

Oestrogenic activity of anol; a highly active phenol isolated from the byproducts.

CAMPBELL, N. R.

Isolation of hexoestrol. With E. C. Dodds and W. Lawson.

1938

#3801.1

A syndrome of infantilism, congenital webbed neck, and cubitus valgus.

TURNER, Henry Hubert (1892 – 1970)

“Turner’s syndrome”.

1938

#5045.1

The preparation of anti-typhoid serum in the horse for therapeutic use in man.

FELIX, Arthur (1887 – 1956)
FELIX, Arthur (1887 – 1956) PETRIE, George Ford (1863 – 1955)

Typhoid antiserum.

1938

#5308.1

Demonstratión de un treponema en el borde activo un caso de pinto de las manos y pies y en la linfa de ganglios superficiales (reporte preliminar).

SAENZ RICART, Braulio (1886 – 1961)

B. Saenz, J. Grau Triana, and J. Alfonso Armenteros indicated that pinta is caused by a treponeme, T. carateum.

1939

#2576.8

An electrophoretic study of immune sera and purified antibody preparations.

TISELIUS, Arne Wilhelm Kaurin (1902 – 1971)
TISELIUS, Arne Wilhelm Kaurin (1902 – 1971)
KABAT, Elvin Abraham (1914 – 2000)
KABAT, Elvin Abraham (1914 – 2000)

Antibodies shown to be gamma globulins.

1939

#3802

The endocrine glands

GOLDZIEHER, Maximilian A. (1883 – 1969)

Goldzieher dealt very fully with the history, theory, and practice of endocrinology.

1939

#3803

Clinical use of triphenylchlorethylene.

MACPHERSON, Archibald Ian Stewart ROBERTSON, Edwin Moody (1902 – 1977)

1939

#3877

Treatment of adrenal insufficiency by means of subcutaneous implants of pellets of desoxycorticosterone acetate (a synthetic adrenal cortical hormone).

THORN, George Widmer (1906 – 2004) & et al.

With L. L. Engel and H. Eisenberg. For treatment of Addison’s disease by the same method, see the same journal, pp. 339-65.

1939

#3907

Experimental diabetes insipidus.

BIGGART, Sir John Henry (1905 – 1979) ALEXANDER, George Lionel (1902 – 1970)

Production of diabetes insipidus in dogs by injury to the hypothalamus.

1939

#4152.1

Familial benign chronic pemphigus.

HAILEY, William Howard (1898 – 1967) HAILEY, Hugh Edward (1909 – 1963)

“Hailey–Hailey disease”, earlier described by H. Gougerot, Arch. derm. – syph. Clin. St Louis, 1933, 5, 255-57.

1939

#5087.2

A study in active immunization against pertussis.

KENDRICK, Pearl Louella (1890 – 1980) ELDERING, Grace (1900 – 1988)

Pertussis vaccine.

1939

#5172.1

The use of anthrax vaccines prepared from avirulent (uncapsulatec) variants of Bacillus anthracis.

STERNE, Max (1905 – 1997)

Nonencapsulated spore vaccine.

1940

#1173.1

Interstitial cell stimulating hormone. II. Method of preparation and some physico-chemical studies.

EVANS, Herbert McLean (1882 – 1971)
EVANS, Herbert McLean (1882 – 1971)
LI, Choh Hao (1913 – 1987)
LI, Choh Hao (1913 – 1987)
SIMPSON, Miriam Elizabeth (1894 – 1991)
SIMPSON, Miriam Elizabeth (1894 – 1991)

Choh Hao Li and colleagues isolated of the interstitial cell stimulating (luteinizing) hormone.

1940

#5398.1

Epidemic and endemic typhus. Protective value for guinea pigs of vaccines prepared from infected tissues of the developing chick embryo.

COX, Herald Rea (1907 – 1986) BELL, E. John

Typhus vaccine.

1940

#7063

Obesity and leanness.

RONY, Hugo R.

The first American book specifically devoted to obesity research.

1940

#7830

Appearance of skeletal abnormalities in the offspring of rats on a deficient diet.

WARKANY, Josef (1902 – 1992) NELSON, R. C.

Warkany was the first to prove that congenital developmental disorders can be induced by exogenous factors in mammals. His studies led to the definition of both genetic and environmentally induced structural defects. …

1940

#10706

On the occurrence of a factor in human serum activating the specific agglutination of sheep blood corpuscles.

WAALER, Erik (1903 – 1997)

Discovery of the Rheumatoid factor.

1941

#2578

The absorption of influenza virus by red cells and a new in vitro method of measuring antibodies for influenza virus.

HARE, Ronald (1899 – 1986) MCCLELLAND, Laurella (1912 – 1993)

Independently of Hirst, McClelland and Hare discovered virus hemagglutination.

1941

#4153

En ny og spesifikk kutan-reaksjon ved Boecks sarcoid. En foreløbig meddelelse.

KVEIM, Morten Ansgar (1892 – 1966)

Kveim’s test for sarcoidosis.

1942

#2237

Diffuse collagen disease; acute disseminated lupus erythematosus and diffuse scleroderma.

KLEMPERER, Paul (1887 – 1964) & et al.

P. Klemperer, A. D. Pollack, and G. Baehr combined a number of diseases, hitherto regarded as unrelated, into an entity which they termed diffuse collagen disease.

1942

#2578.1

Sensitization to horse serum by means of adjuvants.

FREUND, Jules Thomas (1891 – 1960) MCDERMOTT, Katherine

Freund’s adjuvant. Freund’s procedure allowed adjuvants to be used for any antigen.

1942

#2578.2

Pneumococcus polysaccharide as a paralyzing agent on the mechanism of immunity in white mice.

FELTON, Lloyd Derr (1885 – 1953) OTTINGER, Barbara

1942

#2578.3

Experiments on transfer of cutaneous sensitivity to simple compounds.

LANDSTEINER, Karl (1868 – 1943)
LANDSTEINER, Karl (1868 – 1943)
CHASE, Merrill Wallace (1905 – 2004)
CHASE, Merrill Wallace (1905 – 2004)

Cellular transfer of delayed hypersensitivity, establishing the criticial role of mononuclear cells in cellular immunity.

1942

#3804

Syndrome characterized by gynecomastia, aspermatogenesis without A-Leydigism, and increased excretion of follicle-stimulating hormone.

KLINEFELTER, Harry Fitch Jr. (1912 – 1990)
KLINEFELTER, Harry Fitch Jr. (1912 – 1990)

Klinefelter syndrome. With E. C. Reifenstein and F. Albright.

1942

#3853

Application of radioactive iodine in therapy of Graves’s disease.

HERTZ, Saul (1905 – 1950)
HERTZ, Saul (1905 – 1950) ROBERTS, A

1942

#4154

Dermatite papulo-squameuse atrophiante.

DEGOS, Robert (1904 – 1987) & et al.

“Degos’s disease”, malignant atrophic papulosis. With J. Delort and R. Tricot. Earlier described by W. Köhlmeier, Frankf. Z. Path., 1940, 54, 413.

1943

#1174

Adrenocorticotropic hormone.

EVANS, Herbert McLean (1882 – 1971)
EVANS, Herbert McLean (1882 – 1971)
LI, Choh Hao (1913 – 1987)
LI, Choh Hao (1913 – 1987)
SIMPSON, Miriam Elizabeth (1894 – 1991)
SIMPSON, Miriam Elizabeth (1894 – 1991)

Choh Hao Li and colleagues Isolated pure adrenocorticotropic hormone (ACTH) from sheep pituitary glands.

1943

#1175

Preparation and properties of pituitary adrenocorticotropic hormone.

SAYERS, George (1914 – ) LONG, Cyril Norman Hugh (1901 – 1970) WHITE, Abraham

Isolation of ACTH from swine pituitaries.

1943

#2578.4

The fate of skin homografts in man.

GIBSON, Thomas (1915 – 1993)
MEDAWAR, Sir Peter Brian (1915 – 1987)
MEDAWAR, Sir Peter Brian (1915 – 1987)

Gibson and Medawar placed the laws of transplantation on a firm scientific basis. A later paper by Medawar (J. Anat. [Lond.], 1944, 78, 176- 99) demonstrated that the mechanism of rejection of transplanted tissues is …

1943

#3854

Treatment of hyperthyroidism with thiourea and thiouracil.

ASTWOOD, Edwin Bennett (1909 – 1976)

Astwood was the first to treat human cases of hyperthyroidism with thiourea and thiouracil.

1943

#4010

Technique de traitement du lupus tuberculeux.

CHARPY, Jacques (1900 – 1957)

Introduction of calciferol in the treatment of lupus. A more extensive report, “Le traitement des tuberculoses cutanées par la vitamine D2 à hautes doses”, appeared in the same journal, 1946, 8 sér., 6, 310-46.

1944

#2605.2

Penetration of allergens into the human skin.

SULZBERGER, Marion Baldur (1895 – 1983)

Proof that allergens that produce urticarial reactions can penetrate the skin from external contact and thus produce the reaction that the authors named “contact urticaria.” With F. Herrmann and R. Baer.

1944

#3924.1

Incipient myelomatosis or “essential” hyperglobulinemia with fibrino-genopenia – a new syndrome?

WALDENSTRÖM, Jan Gösta (1906 – 1996)

“Waldenström’s macroglobulinemia”.

1944

#5449.1

Chemical, clinical, and immunological studies on the products of human plasma fractionation. XII. The use of concentrated normal human serum gamma globulin (human immune serum globulin) in the prevention and attenuation of measles.

ORDMAN, Charles William (1914 – ) & et al.

Gamma globulin used for passive immunization against measles. With C. G. Jennings and C. A. Janeway.

1945

#1175.1

Isolation and properties of the anterior hypophyseal growth hormone.

EVANS, Herbert McLean (1882 – 1971)
EVANS, Herbert McLean (1882 – 1971)
LI, Choh Hao (1913 – 1987)
LI, Choh Hao (1913 – 1987)
SIMPSON, Miriam Elizabeth (1894 – 1991)
SIMPSON, Miriam Elizabeth (1894 – 1991)

Choh Hao Li and colleagues isolated the anterior pituitary growth hormone.

1945

#3855

Some observations on the use of thiobarbital as an antithyroid agent in the treatment of Graves’s disease.

ASTWOOD, Edwin Bennett (1909 – 1976)

Clinical introduction of thiobarbital.

1945

#3869

A tentative test for pheochromocytoma.

ROTH, Grace M. (1894 – 1982) KVALE, Walter Frederick (1907 – 1970)

The Roth–Kvale histamine test for the diagnosis of pheochromocytoma.

1945

#4011

Lupus vulgaris treated with calciferol.

DOWLING, Geoffrey Barrow (1891 – 1976) THOMAS, Ebenezer William Prosser

Dowling and Prosser Thomas introduced calciferol in the treatment of lupus independently of Charpy (no. 4010) whose work was unknown to them owing to the wartime isolation of France.

1945

#5399

Cultivation of Rickettsia tsutsugamushi in lungs of rodents. Preparation of a scrub-typhus vaccine.

FULTON, Forrest (1913 – 1971) JOYNER, L

Scrub-typhus vaccine.

1945

#5475.1

Production of immunity to dengue with virus modified by propagation in mice.

SABIN, Albert Bruce (1906 – 1993)
SABIN, Albert Bruce (1906 – 1993) SCHLESINGER, Robert Walter (1913 – 2003)

Successful propagation of dengue in mice and production of a vaccine.

1945

#14284

Acetylation of sulfanilamide by liver homogenates and extracts.

LIPMANN, Fritz Albert (1899 – 1986)
LIPMANN, Fritz Albert (1899 – 1986)

Discovery of co-enzyme A and its importance for intermediary metabolism. This discovery illuminated “the process by which cells make available the energy to drive their manufacturing processes” (Judson, p. 245). In 19…

1946

#3924.2

Heredopathia atactica polyneuritiformis; a familial syndrome not hitherto described.

REFSUM, Sigvald Bernhard (1907 – 1991)

“Refsum’s syndrome”, an inherited disorder of lipid metabolism.

1946

#5544.2

Immunity in mumps. VI. Experiments on the vaccination of human beings with formolized mumps virus.

ENDERS, John Franklin (1897 – 1985) STOKES, Joseph Jr. (1896 – 1972) & et al.

With E. P. Maris, and L. W. Kane.

1946

#9338

Radioactive iodine therapy: Effect on functioning metastases of adenocarcinoma of the thyroid.

SEIDLIN, Samuel M. (1895 – 1955)
MARINELLI, Leonidas D. (1906 – 1974)
MARINELLI, Leonidas D. (1906 – 1974) OSHRY, Eleanor

Seidlin and Marinelli described the first successful treatment of a patient with thyroid cancer metastases using radioiodine (I-131). This paper demonstrated the potential of nuclear medicine as a medical specialty.

1947

#6234

Reacción diagnóstica del embarazo en la que se usa el sapo macho como animal reactivo.

GALLI MAININI, Carlos (1914 – 1961)

Male toad test. An English account is in J. clin. Endocr., 1947, 7, 653-58.