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Browse across eight MeSH (opens in new tab) facets — era, geography, science, specialty, technology, history, culture, and reference. Select one tag per group; counts update across the others. What’s new in facet browse how facets relate to subjects and MeSH.
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924 entries match Physiology & Embryology [G07 / G02.149]
1968
#11551
Hydrodynamics and hydraulics by Daniel Bernoulli and Johann Bernoulli. Translated by Thomas Carmody and Helmut Kobus.
Daniel Bernoulli’s Hydrodynamica, published in 1738, marks the first appearance of many topics central to modern science - from the kinetic theory of gases to the principles of jet propulsion. John Bernoulli’s Hydraul…
1968
#12282
Response to exercise after bed rest and after training.
Order of authorship in the original publication: Saltin, Blomqvist, Mitchell, Johnson, Wildenthal, Chapman. Chapman planned the Dallas Bed Rest and Training Study, which defined the degree to which the level of habitu…
1968
#13947
The integrated state of viral DNA in SV40-transformed cells.
Dulbecco and his group demonstrated that the infection of normal cells with certain types of viruses (oncoviruses) led to the incorporation of virus-derived genes into the host-cell genome, and that this event lead to…
1969
#1588.6
Ideas of life and matter; studies in the history of general physiology 600 B.C. to A.D. 1900. 2 vols.
1969
#532.4
Early stages of fertilization in vitro of human oocytes.
First successful in-vitro fertilization of human oocytes. In 2010 Robert Edwards was awarded the Nobel Prize in Physiology or Medicine "for the development of in vitro fertilization."
1969
#2883.8
Catheter technique for recording His bundle activity in man.
Scherlag was the first person to consistently record atrial ventricular bundle ("His bundle") potentials, which served as one of the cornerstones of clinical electrophysiology. With 5 co-authors.
1969
#2578.39
The covalent structure of an entire ÁG immunoglobulin molecule.
Complete sequence of an immunoglobulin molecule. With five coauthors. In 1972 Edelman shared the Nobel Prize in Physiology or Medicine with R. R. Porter “for their discoveries concerning the chemical structure of anti…
1970
#1588.5
Die Entwicklung der physiologischen Methodik von 1784 bis 1911. Eine qualitative Untersuchung.
1970
#1588.7
Mind, brain and adaptation in the nineteenth century. Cerebral localization and its biological context from Gall to Ferrier.
1970
#2660.22
Viral RNA-dependent DNA polymerase: RNA-dependent DNA polymerase in virions of RNA tumour viruses.
In 1970 Baltimore and Temin discovered that certain viruses that have their genes in the form of RNA can copy the RNA "backward" into DNA in infected cells. The enyzme, reverse transcriptase, enables the manufacture o…
1970
#2660.23
RNA-dependent DNA polymerase in virions of Rous sarcoma virus.
Discovery of reverse transcriptase. "In 1969, Temin and a postdoctoral fellow, Satoshi Mizutani, began searching for the enzyme that was responsible for the phenomenon of viral RNA being transferred into proviral DNA.…
1970
#6889
A restriction endonuclease from Hemophilus influenzae. II. Base sequence of the recognition site.
Discovery of the first type II restriction enzyme (HindII). Smith shared the 1978 Nobel Prize in Physiology or Medicine with Werner Arber and Daniel Nathans "for the discovery of restriction enzymes and their applicat…
1970 –1971
#7550
Descriptive catalogue of the physiological series in the Hunterian Museum of the Royal College of Surgeons of England. 2 vols.
Part 1: Surviving Hunterian specimens demonstrating those organs in plants and animals for the special purposes of the individual. Part 2: Hunterian specimens demonstrating the products of generation together with sur…
1970
#11112
The human placenta.
An elegantly published and illustrated monograph with extensive historical material.
1970
#12321
Australia antigen (a hepatitis-associated antigen). Purification and physical properties.
Purification of the Australia antigen and investigation of its physical properties. (Order of authorship in the original publication: Millman, Loeb, Bayer, Blumberg.) Blumberg shared the 1976 Nobel Prize in Physiology…
1970
#14232
Characterization of ovine hypothalamic hypophysiotropic TSH-releasing factor.
Working with sheep preparations, the authors determined that the molecular structure of TRF (thyroid releasing hormone), is 2-pyrrolidone-5-carboxylyl-histidyl-L-proline amide. On page 324, they showed the molecular s…
1971
#4729.2
Transmission of two subacute spongiform encephalopathies of man (Kuru and Creutzfeldt–Jakob disease) to New World monkeys.
Following Hadlow's suggestion (1959), Gadjusek was able to transmit Kuru and Creutzfeldt–Jakob disease to primates through cerebral inoculations. Similarity in the clinical course of the diseases and in the cellular p…
1971
#534.4
Les sciences de la vie dans la pensée française du XVIIIe siècle. Genération des animaux de Descartes à l’Encyclopédie. 2e ed.
Translated into English by Robert Ellrich as The life sciences in eighteenth-century French thought, edited by Keith R. Benson, Stanford: Stanford University Press, 1998.
1971
#6890
Specific cleavage of simian virus 40 DNA by restriction endonuclease of Hemophilus influenzae.
Nathans showed that the restriction enzyme discovered by Hamilton Smith cleaved SV40 DNA into 11 specific pieces. Nathans and his student Kathleen Danna wrote: "The availability of pieces of SV40 DNA from specific sit…
1971
#13958
Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs.
In 1982 Vane shared the Nobel Prize in Physiology or Medicine with Sune Bergström and Bengt Samuelsson for "their discoveries concerning prostaglandins and related biologically active substances."
1971
#14231
Structure of the porcine LH-and FSH-releasing hormone. II. Confirmation of the proposed structure by conventional sequential analyses.
Publication in May 1971: Working with pig preparations, the authors reinvestigated the peptide that they had previously isolated, which acted as an LH-FSH releasing hormone. They performed an Edman-dansyl degradation …
1971
#14258
The hippocampus as a spatial map. Preliminary evidence from unit activity in the freely-moving rat.
See also: O'Keefe, "Place units in the hippocampus of the freely moving rat," Experimental Neurology, 51 (1976) 78–109. O’Keefe and his student Jonathan Dostrovsky discovered place cells in the hippocampus, and that t…
1972
#1588.10
A history of biochemistry. 5 vols.
Forms vols. 30-34 of Comprehensive biochemistry, edited by M. Florkin and E. H. Stotz.
1972
#1588.11
Machina carnis: the biochemistry of muscular contraction in its historical development.
A definitive history of the development of knowledge on muscle biochemistry; valuable bibliography.
1972
#2578.29
Histocompatibility-linked immune response genes.
Benacerraf and McDevitt discovered that the capacity to mount certain immune responses is genetically determined. In 1980 Benacerraf shared the Nobel Prize in Physiology or Medicine with J. Dausset and G. D. Snell "fo…
1972
#13806
Materials and clothing in health and disease by E. T. Renbourn (with The biophysics of clothing materials by W. H. Rees).
1973
#1588.12
History of physiology. Edited and translated by G. B. Risse
A revised and expanded translation of Geschichte der Physiologie, Berlin, 1953.
1973
#1588.13
The heart and the vascular system in ancient Greek medicine from Alcmaeon to Galen.
1973
#2700.4
Computerized transverse axial scanning (tomography).
Hounsfield invented computer-assisted tomography (CAT), or computed tomography (CT). In 1979 Hounsfield shared the Nobel Prize in Physiology or Medicine with Allen M. Cormack "for the development of computer assisted …
1973
#2700.5
Image formation by induced local interactions: Examples employing nuclear magnetic resonance.
Lauterbur proposed a workable method for using nuclear magnetic resonance to produce images of tissues. In 2003 Lauterbur shared the Nobel Prize in Physiology or Medicine with Sir Peter Mansfield “for their discoverie…
1973
#11074
Identification of a novel cell type in peripheral lymphoid organs in mice. I. Morphology, quantitation, tissue distribution.
Order of authorship in the original publication: Steinman, Cohn. In this paper Steinman announced his discovery of the dendritic cell. Digital facsimile from PubMedCentral at this link. In 2011 Steinman received half …
1973
#14241
Regulation of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase activity in human fibroblasts by lipoproteins.
Goldstein and Brown discovered that human cells have low-density lipoprotein (LDL) receptors that remove cholesterol from the blood and that when LDL receptors are not present in sufficient numbers, individuals develo…
1974
#1588.14
The way in and the way out. François Magendie, Charles Bell and the roots of the spinal nerves. With a facsimile of Charles Bell’s annotated copy of his Idea of a new anatomy of the brain. Edited by Paul Cranefield.
An annotated bibliography of the literature documenting the history of this controversy together with reproductions of the texts of the crucial papers. See Nos. 1254-1259.
1974
#534.41
Foundations of experimental embryology. 2nd ed.
14 classic contributions to embryology (in English translations where appropriate) with historical commentaries.
1974
#7453
Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system.
Doherty and Zinkernagel discovered how a class of white blood cells known as T cells kill virus-infected cells in the body, and so present the spread of viruses. In 1998 Zinkernagel and Doherty were awarded the Nobel …
1974
#9941
The genetics of CAENORHABDITIS ELEGANS.
In 2002 Brenner shared the Nobel Prize in Physiology or Medicine in Physiology or Medicine with H. Robert Horvitz and John Sulston "for their discoveries concerning genetic regulation of organ development and programm…
1974
#9942
The DNA of CAENORHABDITIS ELEGANS.
Digital facsimile from PubMedCentral at this link.
1974
#13934
Genetic control of the cell division cycle in yeast.
In 2001 Hartwell shared the Nobel Prize in Physiology or Medicine with Tim Hunt and Sir Paul M. Nurse "for their discoveries of key regulators of the cell cycle." See also No. 13933. In this paper the authors demonstr…
1975
#1588.15
The neurosciences: Paths to discovery.
Thirty-one contributions to a symposium in honour of F. O. Schmitt.
1975
#1588.16
Translations in respiratory physiology.
English translations of 22 classic papers (some quite lengthy) with introductions by various experts.
1975
#2660.27
From the molecular biology of oncogenic DNA viruses to cancer. Les Prix Nobel en 1975, pp. 172-80.
In 1975 Dulbecco shared the Nobel Prize in Physiology or Medicine with David Baltimore and Howard Martin Temin "for their discoveries concerning the interaction between tumour viruses and the genetic material of the c…
1975
#2578.43
Continuous cultures of fused cells secreting antibody of predefined specificity.
Hybridomas. In 1984 Köhler and Milstein shared the Nobel Prize in Physiology or Medicine with Niels K. Jerne, "for theories concerning the specificity in development and control of the immune system and the discovery …
1975
#11691
Heart and coronary arteries: An anatomical atlas for clinical diagnosis, radiological investigation, and surgical treatment.
With 1,098 images this is "probablly the highest quality atlas of the heart ever produced" (W. Bruce Fye). This atlas received recognition throughout the world, including a Gold Medal at the International Book Festiva…
1975
#14249
Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma. II. Reconstitution of functional rough microsomes from heterologous components.
"In 1975 Günther Blobel showed that in certain cases amino acids in a protein serve as an address label that determines where a protein is to be delivered. Amino acid sequences determine whether a protein is to be pas…
1976
#2660.28
DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA.
Discovery of the first “oncogene. In 1989 Varmus and Bishop shared the Nobel Prize for in Physiology or Medicine "for their discovery of the cellular origin of retroviral oncogenes."
1976
#7454
Single-channel currents recorded from membrane of denervated frog muscle fibres.
In 1991 Neher and Sakmann were awarded the 1991 Nobel Prize in Physiology or Medicine for "their discoveries concerning the function of single ion channels in cells." They were also awarded the prize for the invention…
1976
#14245
Evidence for somatic rearrangement of immunoglobulin genes coding for variable and constant regions.
Discovery of V(D)J recombination, the genetic mechanism which produces antibody diversity. In 1987 Tonegawa was awarded the Nobel Prize in Physiology or Medicine "for his discovery of the genetic principle for generat…
1976
#14253
Genetic control of the cell division cycle in the fission yeast Schizosaccharomyces pombe.
"Beginning in 1976, Nurse identified the gene cdc2 in fission yeast (Schizosaccharomyces pombe). This gene controls the progression of the cell cycle from G1 phase to S phase and the transition from G2 phase to mitosi…
1977
#8150
Medical imaging by NMR.
Mansfield developed a mathematical technique that would allow NMR scans to take seconds rather than hours and produce clearer images than the technique Paul Lauterbur developed in 1973. Mansfield showed how gradients …
1977
#11043
An amazing sequence arrangement at the 5' ends of adenovirus 2 messenger RNA.
Discovery of introns. In 1993 Roberts shared the Nobel Prize in Physiology or Medicine with Phillip A. Sharp "for their discoveries of split genes." It was frequently suggested that Chow deserved a share of that prize…