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169 entries match General Clinical Medicine [G02] · Diagnostics & Imaging [E01]

1884

#2499

Ueber die isolirte Färbung der Schizomyceten in Schnitt- und Trocken-präparaten.

Gram’s method of staining bacteria (Gram stain). While not all bacteria may be definitively classified in this way, it is almost always the first step in the preliminary identification of a bacterial organism.

1884

#12161

Prophylaxie et géographie médicale: Des principales maladies tributaires de l'hygiène.

Includes several colored world maps of diseases. Digital facsimile from the Internet Archive at this link.

1885

#2503

Die Methoden der Bakterienforschung.

Hueppe, a colleague of Koch, wrote an admirable manual on bacteriological methods, a subject to which he gave several original contributions. English translation, New York, 1886.

1886

#269

Ueber neue Mikroskope.

Fundamental improvements in the microscope were made by Abbe, who was a mathematician. In 1878 he introduced the oil immersion lens; in 1886 he made an apochromatic objective corrected for three colors in which the se…

1887

#2505.1

Eine kleine Modification des Koch’schen Plattenverfahrens.

Petri dish. A similar dish was described by Cornil and Babès (see No. 2501) and by Nicati and Rietsch, Arch. Physiol. norm. path., 1885, 6, 72. Petri was an assistant of Koch.

1890

#2332

Weitere Mittheilungen über ein Heilmittel gegen Tuberkulose.

In 1890, Koch announced the discovery of tuberculin, a substance derived from tubercle bacilli, which he thought was capable of arresting bacterial development in-vitro and in animals. This news gave rise to tremendou…

1891

#2506.1

Ueber Wasserfiltration durch Filter aus gebrannter Infusorienerde.

Berkefeld kieselguhr filter.

1891

#7243

Entsefalometriya mozga cheloveka v otnoshenii k polu, vozrastu i cherepnomu ukazatelyu [in Cyrillic].

In 1889, nearly 20 years before Horsley and Clarke published their paper on the use of stereotaxy to examine the brain, Dmitrii Zernov, a professor of anatomy at Moscow University, invented the first prototype of a st…

1892

#2545.1

Practical results of bacteriological researches.

Sternberg demonstrated that the serum of an animal recovered from vaccinia possesses the property of neutralizing the activity of the causative virus. His test was readily adaptable for use in various host-systems.

1896

#2550

Recherches de la réaction agglutinante dans le sang et le sérum desséchés des typhiques et dans la sérosité des vesicatoires.

Developing the work of Gruber and Durham, Widal noted that a patient’s serum could be tested with bacteria of known type and his disease identified by this means. They demonstrated specific agglutinins in the blood of…

1897

#2550.1

Über specifische Reactionen im keimfreien Filtraten aus Cholera, Typhus und Pestbouillonculturen, erzeugt durch homologes Serum.

The precipitin reaction, employed for the qualitative identification of antigens and antibodies. English translation in Bibel, Milestones in immunology,(1988) pp. 265-68.

1901

#2553

Sur l’existence de substances sensibilisatrices dans la plupart des sérums antimicrobiens.

The Bordet–Gengou complement-fixation reaction is the basis of many tests for infection, notably the Wassermann test for syphilis, and reactions for gonococcus infection, glanders, hydatid disease. English translation…

1902

#2625

Die Lehre von den Geschwülsten. 2 vols.

“With this book the microscopical epoch in the evolution of the knowledge of cancer may be said to have been brought to a close” (Haagensen).

1904

#2561

Blood immunity and blood relationship, a demonstration of certain blood relationships amongst animals by means of the precipitin test for blood.

1904

#269.1

Mikrophotographische Untersuchungen mit ultraviolettem Licht.

The ultraviolet light microscope was conceived and designed by Köhler.

1906

#2402

Eine serodiagnostische Reaktion bei Syphilis.

The “Wassermann reaction”, a specific diagnostic blood test for syphilis, and a modification of the complement-fixation reaction of Bordet and Gengou. With A. Neisser and C. Bruck.

1907

#2338

Der diagnostische Wert der kutanen Tuberkulinreaktion bei der Tuberkulose des Kindesalters auf Grund von 100 Sektionen.

Introduction of Pirquet’s test – a cutaneous reaction employed in the diagnosis of tuberculosis.

1908

#2339

Ueber eine diagnostische verwertbare Reaktion der Haul auf Einreibung mit Tuberkulinsalbe.

Moro’s percutaneous tuberculin reaction, employed as a diagnostic measure.

1908

#2340

Die kutane und konjunktivale Tuberkulinreaktion, ihre Bedeutung für Diagnostik und Prognose der Tuberkulose.

Wolff-Eisner’s conjunctival tuberculin reaction.

1908

#2341

Intradermo-réaction de la tuberculine.

Mantoux’s intradermal tuberculin skin test.

1908

#5065

Kutanreaktion beil Impfung mit Diphtherietoxin.

The Schick test for the determination of susceptibility to diphtheria.

1908

#12385

Die von Pirquet'sche Hautreaktion und die intravenöse Tuberkulinbehandlung.

First publication on the The Mantoux test or Mendel–Mantoux test (also known as the Mantoux screening test, tuberculin sensitivity test, Pirquet test, or PPD test for purified protein derivative) is a tool for screeni…

1911

#2851

The mechanism of the heartbeat: With special reference to its clinical pathology.

Sir Thomas Lewis was a pioneer in the application of electrocardiography to clinical medicine. His book was both an exhaustive treatise on the subject for its time, and a valuable bibliographical source. Second editio…

1911

#269.2

Das Fluoreszenzmikroskop.

Fluorescence microscopy

1912

#2840

Electro-cardiography and its importance in the clinical examination of heart affections.

1913

#3647

Die Farbstoffe des Blutserums. 1. Eine quantitative Bestimmung des Bilirubins im Blutserum.

The van den Bergh test.

1913

#5066

Die Diphtherietoxin – Hautreaktion des Menschen als Vorprobe der prophylaktischen Diphtherieheilseruminjektion.

Schick developed his test for use as an indication as to whether or not prophylactic injections of antitoxin are necessary in children already exposed to diphtheria. English translation in J. Mt. Sinai Hosp., 1938, 5,…

1918 –1973

#82

Sebrané spisy. Opera omnia. Tom. 1-12.

Purkynĕ was Professor of Physiology at Breslau and Prague. Eminent as physiologist and microscopist, he was first to use the microtome. See Kruta, V. J.E. Purkynĕ, Physiologist. A short account of his contributions…wi…

1918

#2894.1

Angina pectoris: changes in electrocardiogram during paroxysm.

First electrocardiogram recorded (1917) from a patient with angina pectoris.

1918

#5081

Serologische Beobachtungen am Scharlachexanthem.

Schultz–Charlton reaction.

1919

#2440

On the value of a skin reaction to a suspension of leprous nodules.

Mitsuda (lepromin) reaction. English translation by the author in Int. J. Leprosy, 1953, 21, 347-58.

1919 –1920

#3850

Epinephrin hypersensitiveness test in the diagnosis of hyperthyroidism.

Goetsch devised a skin reaction test for use in the diagnosis of hyperthyroidism

1919

#3922

A system of blood analysis.

Folin–Wu test for blood sugar.

1919

#12006

The use of blood agar for the study of streptococci.

In this monograph with numerous charts and 34 full-page plates Brown classified streptococci into α, β, A prime and γ based on the type and degree of hemolysis produced by the bacteria on a blood agar plate. He also d…

1921

#1527

Atlas der Spaltlampenmikroskopie des lebenden Auges.

An important work on the biomicroscopy of the eye. Second ed. greatly revised and enlarged, vol. 1-2, Springer, 1930-31; vol. 3, Stuttgart, F. Enke, 1942; vol. 3 (English translation) Zurich, 1947. Second ed. reprinte…

1922

#2412

A simple quantative precipitation reaction for syphilis.

Kahn test.

1922

#2413

Studies in the standardization of the Wassermann reaction. XXX. A new complement-fixation test for syphilis based upon the results of studies in the standardization of technic.

Kolmer test.

1924

#5069

Ueber cutane Hautreaktion mittels Diphtherie-Toxin zum Nachweis der Diphtherie-Immunität.

The “scratch test”, a cutaneous reaction for determination of susceptibility to diphtheria.

1924

#5082

A skin test for susceptibility to scarlet fever.

The “Dick test” for the determination of individual susceptibility to scarlet fever.

1926

#2650

Haemagglutinegehalte van het bloedserum bij carcinoompatiënten.

Bendien test for the diagnosis of cancer. He published books in German and English on this subject in 1931. Modification by E. C. Lowe, Brit. med. J., 1932, 2, 1060.

1928 –1929

#4246

Studies of urea excretion.

Blood urea clearance test. With J. F. Mcintosh and D. D. Van Slyke.

1928

#5434

The reaction of the skin of the normal rabbit following intradermal injection of material from smallpox lesions: the specificity of this reaction and its application as a diagnostic test.

McKinnon’s diagnostic test.

1929

#1446

Über das Elektrenkephalogramm des Menschen.

First recording of human brain activity, which Berger called electroencephalography. Berger actually recorded his first EEG in 1924, but did not publish the technique until 1929. He showed that the electrical activity…

1930

#12830

The moving boundary method of studying the electrophoresis of proteins. (Nova Acta Reg. Soc. Scient. Upsaliensis, IV, 7, No. 4.)

Tilesius's doctoral dissertation introduced the laboratory technique of moving-boundary electrophoresis, a technique for separation of chemical compounds by electrophoresis in free solution. For this work, and the wor…

1931

#2524

A new series of graded collodion membranes suitable for general bacteriological use, especially in filterable virus studies.

In his important studies on the filtration of virus preparations, Elford showed that different viruses possessed different and characteristic sizes.

1931

#3923

The analysis of whole-blood. II. The determination of sugar and of saccharoids (non-fermentable copper-reducing substances).

Benedict’s test for blood-sugar.

1932

#2414.1

Studies in the serology of syphilis. VII. A new flocculation test for the serum diagnosis of syphilis.

Eagle flocculation test.

1932

#2863

The electrocardiographic diagnosis of coronary occlusion by the use of chest leads.

Introduction of chest leads.

1932

#5351.1

Precipitin and skin tests as aids in diagnosing trichinosis.

Intradermal test for trichinosis.

1932

#269.3

Beitrag zur geometrischen Elektronenoptik.

Electron microscope. See also their later paper in Z. Physik. 1932, 78, 318.