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Garrison-Morton-Norman History of Medicine

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Drugs & Technology

1,672 entries match Pharmacology & Therapeutics [D01 / E02]

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1943

#5214.1

Use of penicillin in sulfonamide resistant gonorrheal infections.

HERRELL, Wallace Edgar (1909 – 1992) & et al.

With E. N. Cook and L. Thompson.

1943 –1955

#11332

Catalogue of the Ferguson collection of books mainly relating to alchemy, chemistry, witchcraft and gypsies in the Library of the University of Glasgow. 2 vols. including Supplement (1955).

FERGUSON, John (1837 – 1916)

Due to wartime paper rationing only 40 copies of the first printing of the catalogue were published when it was issued in 1943; it was reprinted in the 21st century. Ferguson is best known as the author of the extensi…

1944

#4689.1

Penicillin in the treatment of meningitis.

ROSENBERG, David Harry (1903 – ) ARLING, Philip Arthur (1908 – 1955)

1944

#2028

Untersuchungen über Dextran und sein Verhalten bei parenteraler Zufuhr.

GRÖNWALL, Anders Johan Troed (1912 – 1989) INGLEMAN, Björn

Introduction of dextran as plasma substitute.

1944

#1928.2

The in vitro bacteriostatic action of some simple furan derivatives.

DODD, Matthew Charles (1910 – 1981) STILLMAN, William Barlow (1904 – 1987)

Nitrofuran (nitrofurazone).

1944

#1928.3

Über Konstitution und toxische Wirkung von natürlichen und neuen synthetischen insektentötenden Stoffen.

MÜLLER, Paul Hermann (1899 – 1965) & et al.

Müller introduced Dichlordiphenyltrichlorethane (DDT) as an insecticide. With H. Martin and P. Läuger. In 1948 Müller received the Nobel Prize in Physiology or Medicine "for his discovery of the high efficiency of DDT…

1944

#1935

Streptomycin, a substance exhibiting antibiotic activity against Grampositive and Gram-negative bacteria.

SCHATZ, Albert (1920 – 2005)
WAKSMAN, Selman Abraham (1888 – 1973)
WAKSMAN, Selman Abraham (1888 – 1973) GREGORY, Elizabeth Bugie

Introduction of streptomycin. Order of authorship: Schatz, Gregory, Waksman. In 1952 Waksman was awarded the Nobel Prize in Physiology or Medicine "for ingenious, systematic, and successful studies of the soil microbe…

1944

#2442

Preliminary report on diasone in the treatment of leprosy.

MUIR, Ernest (1880 – 1974)

Muir found diasone (a sulphone) valuable in the treatment of leprosy.

1944

#2659.3

Influence of synthetic oestrogens upon advanced malignant disease.

HADDOW, Sir Alexander (1907 – 1976)
HADDOW, Sir Alexander (1907 – 1976) & et al.

Administration of synthetic estrogens in advanced mammary cancer caused regression of tumors. With J. M. Watkinson, E. Paterson, and P. C. Koller.

1944

#9282

Ethnobotany of the Navajo. Monographs of the School of American Research, No. 8.

ELMORE, Francis Hapgood

Digital facsimile from uair.library.arizona.edu at this link.

1944

#12598

Micro-methods of estimating penicillin blood serum and other bodily fluids.

FLEMING, Sir Alexander (1881 – 1955)
FLEMING, Sir Alexander (1881 – 1955)

Fleming was the first to measure blood levels of penicillin after intramuscular, intradermal, inravenous and continuous drip administration in order to determine the correct dosage. He described his micro-measurement …

1944

#12599

Penicillin content of blood serum after various doses of penicillin by various routes.

FLEMING, Sir Alexander (1881 – 1955)
FLEMING, Sir Alexander (1881 – 1955) SUCHET, Jack (1908 – 2001) & et al.

In this paper Fleming and colleagues explained how to choose routes of administration of penicillin as well as dosage, and reproduced the graphs/figures that showed blood levels achieved with different doses and route…

1945

#2061

Cinchona in Java: The story of quinine.

TAYLOR, Norman (1883 – 1967)

1945

#1928.4

Streptococcal fibrinolysis. A proteolytic reaction due to a serum enzyme activated by streptococcal fibrinolysin.

CHRISTENSEN, Lauritz Royal (1915 – 1997)

Purification and concentration of Tillett and Garner’s (No. 1924.1) substance to produce streptokinase.

1945

#1929

British anti-lewisite (BAL).

PETERS, Sir Rudolph Albert (1889 – 1982)
PETERS, Sir Rudolph Albert (1889 – 1982) & et al.

British Anti-Lewisite BAL (dimercaprol), a medication used to treat acute poisoning by arsenic, mercury, gold, and lead, was discovered during the 1939-45 war. With L. A. Stocken and R. H. S. Thompson.

1945

#1929.1

Effectiveness of a nitrofuran in the treatment of infected wounds.

SNYDER, Marshall Lovejoy (1907 – 1969) & et al.

First clinical use of “furacin” (nitrofuran). With C. L. Kiehn and J. W. Christopherson.

1945

#1936

Bacitracin: a new antibiotic produced by a member of the B, subtilis group.

JOHNSON, Balbina A. (1897 – 1970) & et al.

With H. Anker and F. L. Meleney.

1945

#2350

Streptomycin in treatment of clinical tuberculosis: a preliminary report.

FELDMAN, William Hugh (1892 – 1974) HINSHAW, Horton Corwin (1902 – 2001)

1945

#3104

Detection of weak and “incomplete” Rh agglutinins: a new test.

COOMBS, Robert Royston Amos ( (1921 – 2006) & et al.

Coombs’s test for detecting antibodies in various clinical scenarios, such as Rh disease and blood transfusion. With A. E. Mourant and R. R. Race. A fuller description appears in Brit. J. exp. Path.,1945, 26, 255-66.

1945

#5260

Studies on synthetic antimalarial drugs.

CURD, Francis Henry Swinton (1909 – 1948) & et al.

F. H. S. Curd, D. G. Davey, and F. L. Rose synthesized proguanil (“paludrine”) and first tested it in avian malaria.

1945

#5261

Studies on synthetic antimalarial drugs. XIII. Results of a preliminary investigation of the therapeutic action of 4888 (paludrine) on acute attacks of benign tertian malaria.

ADAMS, Alfred Robert Davies (1901 – 1992)

First use of proguanil in human malaria. With B. G. Maegraith, J. D. King, R. H. Townsend, T. H. Davey, and R. E. Havard.

1945

#12618

The herbal of Rufinus. Edited from the unique manuscript by Lynn Thorndike, assisted by Francis S. Benjamin, Jr.

THORNDIKE, Lynn (1882 – 1965)
THORNDIKE, Lynn (1882 – 1965) RUFINUS (1250 – )

First printed edition of an herbal written circa 1287 by Rufinus, a medieval monk / physician unknown before this edition. Rufinus was titular abbot in absentia of the monastery of Tyre, and plenipotentiary to the arc…

1945

#13061

Plantas medicinale aromaticas o venenosas de Cuba. 2 vols.

ROÍG Y MESA, Juan Tomás (1877 – 1971)

1946

#2062

Die Injektion.

BUESS, Heinrich (1911 – 1984)

Deals exhaustively with the history of intravenous and intramuscular injection.

1946

#2351

Ueber eine neue, gegen Tuberkelbazillen in vitro wirksame Verbindungsklasse.

DOMAGK, Gerhard Johannes Paul (1895 – 1964)
DOMAGK, Gerhard Johannes Paul (1895 – 1964) & et al.

Introduction of thiosemicarbazone in treatment of tuberculosis. With R. Behnisch, F. Mietzsch, and H. Schmidt.

1946

#2359

Chemotherapy of tuberculosis. Researches during the past 100 years.

HART, Philip Montagu D'Arcy (1900 – 2006)

1946

#5261.1

Chloroquine for treatment of acute attacks of vivax malaria.

MOST, Harry (1907 – 1994)
LONDON, Irving M. (1918 – 2018)
LONDON, Irving M. (1918 – 2018) LAVIETES, Paul Harold (1907 – 1990)

Harry Most led the development of chloroquine for use in treating American troops suffering from malaria. At the beginning of the American involvement in the war there were more American casualties from malaria than f…

1946

#10133

Nitrogen mustard therapy. Use of methyl-bis(beta-chloroethyl)amine hydrochloride and tris(beta-chloroethyl)amine hydrochloride for Hodgkin's disease, lymphosarcoma, leukemia and certain allied and miscellaneous disorders.

GOODMAN, Louis Sanford (1906 – 2000)
GOODMAN, Louis Sanford (1906 – 2000)
GILMAN, Alfred Zack (1908 – 1984)
GILMAN, Alfred Zack (1908 – 1984) WINTROBE, Maxwell Myer (1901 – 1986) DAMESHEK, William (1900 – 1969)

Widely considered the first uses of chemotherapy for the treatment of malignant diseases.

1946

#12623

Penicillin: Its practical application. Edited by Sir Alexander Fleming.

FLEMING, Sir Alexander (1881 – 1955)
FLEMING, Sir Alexander (1881 – 1955)

This was the only book that Fleming ever published on penicillin. American issue, Philadelphia: Blakiston, 1946.

1947

#2063

A critical study of the origins and early development of hypodermic medication.

HOWARD-JONES, Norman (1909 – 1985)

1947

#2090

Curare, its history, nature, and clinical use.

MCINTYRE, Archibald Ross (1902 – )

1947

#1937

“Aerosporin”, an antibiotic produced by Bacillus aerosporus Greer.

AINSWORTH, Geoffrey Clough (1905 – 1998)
AINSWORTH, Geoffrey Clough (1905 – 1998) & et al.

Discovery of aerosporin (polymyxin). With A. M. Brown and G. Brownlee.

1947

#1938

Chloromycetin, a new antibiotic from a soil actinomycete.

EHRLICH, John (1907 – 1992) & et al.

Production of chloramphenicol from Streptomyces venezuelae. With Q. R. Bartz, R. M. Smith, D. A. Joslyn and P. R. Burkholder.

1947

#1939

Procaine penicillin G (duracillin); a new salt of penicillin which prolongs the action of penicillin.

HERRELL, Wallace Edgar (1909 – 1992) HEILMAN, Fordyce Russell (1905 – 1960) & et al.

Procaine benzylpenicillin also known as penicillin G procaine was developed by Herrell and colleagues. With D.R. Nichols.

1947

#1941

Polymyxin: a new chemotherapeutic agent.

STANSLY, Philip Gerald (1912 – 1998) & et al.

With R. G. Shepherd and H. J. White.

1947

#5351.3

Experimental chemotherapy of filariasis. III. Effect of 1-diethylcarbamyl-4-methyl-piperazine hydrochloride against naturally acquired filarial infections in cotton rats and dogs.

HEWITT, Reginald Irving (1911 – ) & et al.

Proof of antifilarial action of diethylcarbarmazine citrate (hetrazan). With S. Kushner, H. W. Stewart, E. White, W. S. Wallace, and Y. Subbarow.

1947

#5351.4

Sur la chimiothérapie de l’onchocercose. (Note préliminaire).

VAN HOOF, L.

First effective chemotherapy (suramin) for onchocerciasis. With C. Heurard, E. Peel, and M. Wanson.

1947

#1940

Chloromycetin, an antibiotic with chemotherapeutic activity in experimental rickettsial and viral infections.

SMADEL, Joseph Edwin (1907 – 1963) JACKSON, Elizabeth B.

Introduction of chloramphenicol, used in treatment of typhus.

1947

#6940

Nicolaus Pol Doctor 1494 by Max H. Fisch. With a critical text of his guaiac tract, edited with a translation by Dorothy M. Schullian.

SCHULLIAN, Dorothy May (1906 – 1989) POL, Nicolaus (1467 – 1532) FISCH, Max Harold (1900 – 1995)

The 1494 in the title comes from the year in which Pol became a physician, and his habit of writing his name and that date in his books. The volume includes a study of books from Nicolaus Pol's library in Cleveland an…

1947

#9343

Healing herbs of the upper Rio Grande.

CURTIN, Leonora Scott Muse (1879 – 1972)
CURTIN, Leonora Scott Muse (1879 – 1972) MOORE, Michael Roland Shaw (1941 – 2009)

Revised and edited by Michael Moore as Healing herbs of the upper Rio Grande: Traditional medicine of the Southwest (Sante Fe: Western Edge Press, 1997).

1947

#13043

Physicians' desk reference to pharmaceutical specialties and biologicals. Richard R. Maehler, Editor of Compilation and Arrangement.

MAEHLER, Richard R.

This work underwent its 71st edition in 2017.

1947

#13113

The effects of atomic bombs on health and medical services in Hiroshima and Nagasaki. The United States Strategic Bombing Survey, Medical Division.

UNITED STATES STRATEGIC BOMBING SURVEY, MEDICAL DIVISION

Digital facsimile from U.S. National Library of Medicine at this link.

1947

#13496

La contribución del Ecuador a la material médica: La quina.

PAREDES BORJA, Virgilio (1858 – 1983)

1948

#2010.3

A linear electron accelerator.

GINZTON, Edward Leonard (1915 – 1998) HANSEN, William Webster (1909 – 1949) & et al.

With W. R. Kennedy.

1948

#2091

The sensitizing effect of tetraethylthiuramdisulphide (Antabuse) to ethyl alcohol.

HALD, Jens

Introduction of “antabuse” in the treatment of alcoholism. With E. Jacobsen and V. Larsen. See also Lancet, 1948, 2, 1004.

1948

#1929.4

A study of the adrenotropic receptors.

AHLQUIST, Raymond Perry (1914 – 1983)

Described the concept of α and β adrenergic receptors in the sympathetic nervous system, and placed specific receptors into pharmacologic mechanisms.

1948

#1943

Ricerche su di un nuovo antibiotico.

BROTZU, Giuseppe (1895 – 1976)
BROTZU, Giuseppe (1895 – 1976)

Brotzu showed that a Cephalosporium acremonium filtrate inhibited the growth of Gram-positive and -negative organisms.

1948

#2442.1

Leprosy treated with sulphetrone in 1943.

HARKNESS, Arthur Herbert (1889 – 1970) BROWNLEE, G

Clinical use of solapsone (sulphetrone).

1948

#2660.1

Temporary remissions in acute leukemia in children produced by folic acid antagonist 4-amethopteroylglutamic acid (aminopterin).

FARBER, Sidney (1903 – 1973)
FARBER, Sidney (1903 – 1973)

With L. K. Diamond, R. D. Mercer, R. F. Sylvester, and V. A. Wolff.

1948

#3107.1

Replacement transfusion as a treatment for erythroblastosis fetalis.

DIAMOND, Louis Klein (1902 – 1999)

Exchange transfusion.