Skip to main content
Garrison-Morton-Norman History of Medicine

Facets

Browse across eight MeSH (opens in new tab) facets — era, geography, science, specialty, technology, history, culture, and reference. Select one tag per group; counts update across the others. What’s new in facet browse how facets relate to subjects and MeSH.

Clear filters

Historical Eras

Geography

Natural & Physical Sciences

Specialties & Disease

Social & Historical Studies

Institutions & Culture

Reference & Scholarly Works

Drugs & Technology

1,672 entries match Pharmacology & Therapeutics [D01 / E02]

Sort by YearSort by Author

1948

#2880

Penicillin in subacute bacterial endocarditis. Report to the Medical Research Council on 269 patients treated in 14 centres appointed by the Penicillin Clinical Trials Committee.

CHRISTIE, Ronald Victor (1902 – 1986)

1948

#1929.3

Curare-like action of polymethylene bis-quaternary ammonium salts.

PATON, Sir William Drummond Macdonald (1917 – 1993)
PATON, Sir William Drummond Macdonald (1917 – 1993) ZAIMIS, Eleanor (1915 – 1982)

Methonium compounds. See also the same journal, 1948, 162, 810.

1948

#5261.2

Pentaquine (Sn-13,276), a therapeutic agent effective in reducing the relapse rate in vivax malaria.

ALVING, Alf Sven (1902 – 1965)

Clinical trials of pentaquine. With B. Craige, R. Jones, C. M. Whorton, T. N. Pullman, and L. Eichelberger.

1948

#7786

No place to hide.

BRADLEY, David John (1915 – 2008)

Bradley's autobiographical account of his work in the Radiological Safety Section in the Pacific in the aftermath of the Bikini atomic bomb tests, Operation Crossroads, alerted the world to the dangers of radioactive …

1948

#7802

The estimation of acetanilide and its metabolic products, aniline, N-acetyl p-aminophenol and p-aminophenol (free and total conjugated) in biological fluids and tissues.

AXELROD, Julius (1912 – 2004)
AXELROD, Julius (1912 – 2004)
BRODIE, Bernard Beryl (1907 – 1989)
BRODIE, Bernard Beryl (1907 – 1989)

Brodie and Axelrod confirmed that paracetamol, also known as acetaminophen, was the major metabolite of acetanilide in human blood, and established that it was efficacious an analgesic. Unlike its precursors, paraceta…

1948

#7863

Aureomycin; a product of the continuing search for new antibiotics.

DUGGAR, Benjamin Minge (1872 – 1956)

Discovery of clortetracycline (trade name Aureomycin, Lederle) the first tetracycline antibiotic identified. Duggar,a plant physiologist, identified the antibiotic as the product of an actinomycete he cultured from a …

1948

#12359

Orally administered penicillin in patients with rheumatic fever.

MASSELL, Benedict Frank (1906 – 2008) DOW, J. W. JONES, Thomas Duckett (1899 – 1954)

Massell and colleagues demonstrated that rheumatic fever could be prevented by penicillin treatment of streptococcal throat infections. (Order of authorship in the original publication: Massell, Dow, Jones.) See also:…

1949

#2010.4

The microwave linear electron accelerator.

NEWBERRY, G. R.

1949

#2010.5

Therapeutic possibilities of microwaves.

WAKIM, Khalil Georges (1907 – 1985) KRUSEN, Frank Hammond (1898 – 1973) & et al.

Introduction of microwave radiation therapy. With J. F. Herrick, G. M. Martin.

1949

#2064

Histoire illustrée de la pharmacie.

BOUSSEL, Patrice

1949

#2065

A critical review of the basic facts in the history of cinchona.

JARAMILLO-ARANGO, Jaime (1897 – 1962)

1949

#1930

Bradykinin, a hypotensive and smooth muscle stimulating factor releases from plasma globulin by snake venoms and by trypsin.

ROCHA E SILVA, Mauricio (1910 – 1983) & et al.

Discovery of bradykinin. With W. T. Beraldo and G. Rosenfeld.

1949

#1930.1

Lithium salts in the treatment of psychotic excitement.

CADE, John Frederick Joseph (1912 – 1980)
CADE, John Frederick Joseph (1912 – 1980)

The first clinical trial of lithium.

1949

#1944

Neomycin, a new antibiotic active against streptomycin-resistant bacteria, including tuberculosis organisms.

WAKSMAN, Selman Abraham (1888 – 1973)
WAKSMAN, Selman Abraham (1888 – 1973) LECHEVALIER, Hubert Arthur (1926 – 2015)

Isolation of neomycin.

1949

#1945

An antiphage agent isolated from Aspergillus sp.

HANSON, Frederick Reuben (1921 – ) EBLE, Thomas Eugene (1923 – )

Isolation of fumagillin, an antibiotic with amoebicidal activity. See also Science, 1951, 113, 202-3.

1949

#3855.1

Imidazoles. IV. The synthesis and antithyroid activity of some 1-substituted-2-mercaptoimidazoles.

JONES, Reuben G.

Synthesis of methimazole (mercazole, thiamazole), an antithyroid drug more potent than methylthiouracil. With E. C. Kornfeld, K. C. McLaughlin, and R. C. Anderson.

1949

#5727

The pharmacological actions of polymethylene bistrimethyl-ammonium salts.

PATON, Sir William Drummond Macdonald (1917 – 1993)
PATON, Sir William Drummond Macdonald (1917 – 1993) ZAIMIS, Eleanor (1915 – 1982)

Introduction of hexamethonium bromide.

1949

#8514

A dictionary of Assyrian botany.

THOMPSON, Reginald Campbell (1876 – 1941)

1949

#11102

Mushrooms in their natural habitats.

SMITH, Alexander Hanchett (1904 – 1986)

A distinctively published work illustrated stereoscopically with color View-Master slides, and incorporating the View-Master "reels" and a View-Master viewer in a box along with the conventional bound text.

1949

#11228

Bibliotheca chemica et alchemica. An annotated catalogue of printed books on alchemy, chemistry and cognate subjects.

DUVEEN, Denis Ian (1910 – 1992) KLICKSTEIN, Herbert S.

Though he was not credited on the title page, most of this catalogue was written by Herbert S. Klickstein, working for the collector, Denis Duveen.

1949

#12613

Antibiotics: A survey of penicillin, streptomycin, and other antimicrobial substances from fungi, actinomycetes, bacteria, and plants. 2 vols.

ABRAHAM, Sir Edward Penley (1913 – 1999)
CHAIN, Sir Ernst Boris (1906 – 1979)
CHAIN, Sir Ernst Boris (1906 – 1979)
FLOREY, Howard Walter (1898 – 1968)
FLOREY, Howard Walter (1898 – 1968) HEATLEY, Norman George (1911 – 2004) SANDERS, A. G. JENNINGS, Margaret Augusta (1904 – 1994) FLOREY, Lady Mary Ethel (1900 – 1966)

Order of authorship of the original set: H. W. Florey, Chain, Heatley, Jennings, Sanders, Abraham, M. E. Florey.

1949

#12634

The chemistry of penicillin.

ROBINSON, Sir Robert (1886 – 1975)
ROBINSON, Sir Robert (1886 – 1975) CLARKE, Hans Thacher (1887 – 1972) JOHNSON, John Raven (1900 – 1983)

The National Academy of Sciences arranged for the preparation of this summary, with Clarke and Johnson representing the United States on the editorial board, and Robinson representing Britain. The 1120 page book was p…

1949

#12635

X-ray crystallographic investigation of the structure of penicillin. IN: Clarke, Johnson, Robinson (eds.) Chemistry of penicillin (1949) 310-67.

HODGKIN, Dorothy Crowfoot (1910 – 1994) ROGERS-LOW, Barbara Wharton (1920 – 2019)

Hodgkin and colleagues, including biochemist Barbara Low, solved the structure of penicillin in 1945, demonstrating, contrary to scientific opinion at the time, that it contains a β-lactam ring. The discovery was orig…

1950

#2028.1

Prevention of haemolysis during freezing and thawing red blood-cells.

SMITH, Audrey Ursula (1915 – 1981)

Demonstration that human blood diluted with equal volumes of 30% glycerol in Ringer’s lactate solution could be frozen at -79° C and thawed after eight weeks without damage.

1950

#1945.1

Terramycin, a new antibiotic.

FINLAY, Alexander Carpenter (1906 – ) & et al.

Oxtetracycline (terramycin).

1950

#3215.1

Tobacco smoking as a possible etiologic factor in bronchogenic carcinoma: A study of 684 proved cases.

GRAHAM, Evarts Ambrose (1883 – 1957)
GRAHAM, Evarts Ambrose (1883 – 1957) WYNDER, Ernst Ludwig (1922 – 1999)

A case-control study proving an association between heavy prolonged cigarette smoking and bronchogenic carcinoma. See also the following paper on pp. 336-38. Reprinted in J. Amer. med. Assoc. 1985, 253, 2986-97.

1950

#3215.2

Smoking and carcinoma of the lung. Preliminary report.

DOLL, Sir William Richard Shaboe (1912 – 2005)
HILL, Sir Austin Bradford (1897 – 1999)
HILL, Sir Austin Bradford (1897 – 1999)

A study of 1,465 cases of lung cancer and 1,465 matched controls, which confirmed and extended the studies of Wynder and Graham, and others. See also later papers by the same authors in Brit. med. J., 1952, 2,1271-86;…

1950

#5262.3

Primaquine, S.N. 13,272, a new curative agent in vivax malaria: a preliminary report.

EDGCOMB, John Harold (1924 – 2007) & et al.

Introduction of primaquine.

1950

#9185

Variation and evolution in plants.

STEBBINS, George Ledyard Jr. (1906 – 2000)

The first comprehensive exposition of the relationship between genetics and natural selection in plants, and the most imporant book on plant evolution published during the 20th century. Stebbins combined genetics and …

1951

#2067

The development of pharmacopoeias.

URDANG, George (1882 – 1960)

Digital facsimile from PubMedCentral at this link.

1951

#1945.2

Isolation of antibiotics from a species of Cephalosporium. Cephalosporins P1, P2, P3, P4, and P5.

ABRAHAM, Sir Edward Penley (1913 – 1999) BURTON, H. S.

1951

#1945.3

Viomycin, a new antibiotic active against mycobacteria.

FINLAY, Alexander Carpenter (1906 – ) & et al.

Isolation of viomycin. With 11 co-authors.

1951

#1945.4

Fungicidin, an antibiotic produced by a soil actinomycete.

HAZEN, Elizabeth Lee (1885 – 1975)
HAZEN, Elizabeth Lee (1885 – 1975)
BROWN, Rachel Fuller (1898 – 1980)
BROWN, Rachel Fuller (1898 – 1980)

Isolation of nystatin (fungicidin).

1951

#5262.4

2:4-Diaminopyrimidines – a new series of antimalarials.

FALCO, E. A.

Preparation and laboratory tests of pyrimethamine. With L. G. Goodwin, G. H. Hutchings, I. M. Rollo, and P. B. Russell.

1951

#5262.5

A 2:4-diamino pyrimidine in the treatment of proguanil-resistant laboratory malarial strains.

ROLLO, Ian McIntosh (1926 – 2015)

Pyrimethamine (daraprim).

1951 –1952

#7113

Die botanische Buchillustration: Ihre Geschichte und Bibliographie. 2 vols.

NISSEN, Claus (1901 – 1975)

1951

#11699

Tobacco and the cardiovascular system: The effects of smoking and of nicotine on normal persons.

ROTH, Grace M. (1894 – 1982)

1952

#2068

Plants of the Bible.

MOLDENKE, Harold Norman (1909 – 1996) MOLDENKE, Alma Lance Ericson (1908 – 1997)

The most comprehensive treatise available on plants and plant products mentioned in the Bible.

1952

#1931

Reserpin, der sedative Wirkstoff aus Rauwolfia serpentina Benth.

MÜLLER, J. M. & et al.

Isolation of reserpine. With E. Schlittler and H. J. Bein.

1952

#1946

“Ilotycin”, a new antibiotic.

MCGUIRE, James Myrlin (1909 – ) & et al.

Discovery of erythromycin. With R. L. Bunch, R. C. Anderson, H. E. Boaz, E. H. Flynn, H. M. Powell, and J. W. Smith.

1952

#2353

Chemotherapy of human tuberculosis with hydrazine derivatives of isonicotinic acid. (Preliminary report of representative cases.)

ROBITZEK, Edward Heinrich (1912 – 1984) & et al.

Introduction of isoniazid. With I. J. Selikoff and G. G. Omstein. See also Amer. Rev. Tuberc., 1952, 65, 257-442.

1952

#4962.3

Trente-huit cas de psychoses traitées par la cure prolongée et continue de 4560 R. P. C. R. Congr. Alien, et Neurol, de Langue Franç.

DELAY, Jean (1907 – 1987)
DENIKER, Pierre (1917 – 1998)
DENIKER, Pierre (1917 – 1998)

Introduction of chlorpromazine in the treatment of psychosis. Chlorpromazine was later marketed in the United States as Thorazine.

1952

#7764

Incidence of leukemia in survivors of the atom bomb in Hiroshima and Nagasaki, Japan.

FOLLEY, J. H. BORGES, T. YAMASAKI, T.

Leukemia was the first cancer to be linked with radiation exposure in atomic bomb survivors.

1952

#9719

Replica plating and indirect selection of bacterial mutants.

LEDERBERG, Joshua (1925 – 2008)
LEDERBERG, Joshua (1925 – 2008)
LEDERBERG, Esther (1922 – 2006)
LEDERBERG, Esther (1922 – 2006)

Demonstration of the mutational basis of antibiotic resistance. Digital facsimile from PubMedCentral at this link.

1952

#12615

The clinical application of antibiotics. Penicillin.

FLOREY, Lady Mary Ethel (1900 – 1966)

Printed on the title page: "This volume, although a separate publication, is a continuation of the work described in Antibiotics Volumes I and II, and may be read in conjunction with it." (Thanks to Juan Weiss for thi…

1953

#1931.1

Propriétés pharmacodynamiques du chlorhydrate de chloro-3 (diméthylamino-3’propyl) -10 phénothiazine (4.560 R.P.).

COURVOISIER, Simone & et al.

Chlorpromazine. With J. Foumel, R. Ducrot, M. Kolsky, and P. Koetschet. Chloropromazine was later marketed in the United States as Thorazine.

1953

#1931.2

The effects of progesterone and related compounds on ovulation and early development in the rabbit.

CHANG, Min Chueh (1908 – 1991)
CHANG, Min Chueh (1908 – 1991)
PINCUS, Gregory Goodwin (1903 – 1967)
PINCUS, Gregory Goodwin (1903 – 1967)

First practical demonstration of an oral contraceptive.

1953

#2660.4

Aryl-2-halogenoalkylamines. Part XII. Some carboxylic derivatives of NN-Di 2-chloroethylaniline.

EVERETT, James Lionel

Chlorambucil (a nitrogen mustard) used in the chemotherapy of cancer. With J. R. Roberts and W. J. C. Ross.

1953

#9243

The book of plants [Kitâb al-nabât] of Abū Hanīfa ad-Dīnawari: Part of the alphabetical section (j-i). Edited and translated by Bernhard Lewin.

LEWIN, Bernhard IBN DAWŪD DĪNAWARĪ, Ābu Ḥanīfah Āḥmad (815 – 896)

1953 –1959

#9245

La "Materia médica" de Dioscórides: Transmisión medieval y renacentista by César E. Dubler. Vol. I: La transmisión medieval y renacentista y la supervivencia en la medicina popular moderna de la "Materia médica" de Dioscórides, estudiada particularmente en España y África del Norte. Vol. 2: La versión árabe de la 'Materia Médica' de Dioscórides (texto, variantes e indices): estudio de la transcripción de los nombres griegos al árabe y comparación de las versiones griega, árabe y castellana. Vol. 3: La "Materia médica" de Dioscórides traducida y comentada por D. Andrés de Laguna (Texto crítico). Vol. 4: D. Andrés de Laguna y su época. Vol. 5: Glosario médico castellano del siglo XVI. Prólogo de Gregorio Marañón. Vol. 6: Indices generales y léxico especial de Andrés de Laguna.

LAGUNA DE SEGOVIA, Andrés [LACUNA] (1499 – 1559)
DIOSCORIDES, Pedanius [Πεδάνιος Διοσκουρίδης] (40 – 90)
DIOSCORIDES, Pedanius [Πεδάνιος Διοσκουρίδης] (40 – 90) DUBLER, César E. (1915 – 1966)