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411 entries match Chemistry & Biochemistry [K01.900.200]
1946
#14317
Radioactive Element 94 from deuterons on uranium.
"This letter was received for publication on the date indicated (January 28, 1941), but was voluntarily withheld from publication until the end of the war." Seaborg and McMillan discovered element 94, which they named…
1947
#751.4
Enzymatic reactions in carbohydrate metabolism.
In 1947 Carl Cori and his wife Gerty Cori (1896-1957) shared the Nobel Prize (with Houssay) “for their discovery of the course of the catalytic conversion of glycogen.” They are more often remembered for the Cori cycl…
1948
#1929.2
The occurrence of nucleases in culture filtrates of group A hemolytic streptococci.
Streptodornase. See also W. S. Tillett et al., Proc. Soc. exp. Biol. (N. Y.), 1948, 68, 184-88.
1948 –1966
#12191
A bibliographical sourcebook of compressed air, diving and submarine medicine. 3 vols.
Vol. 1 by Hoff; Vols. 2 and 3 by Hoff and Greenbaum, Jr. Digital facsimiles of all three volumes from U.S. National Library of Medicine at this link.
1949
#11228
Bibliotheca chemica et alchemica. An annotated catalogue of printed books on alchemy, chemistry and cognate subjects.
Though he was not credited on the title page, most of this catalogue was written by Herbert S. Klickstein, working for the collector, Denis Duveen.
1949
#12634
The chemistry of penicillin.
The National Academy of Sciences arranged for the preparation of this summary, with Clarke and Johnson representing the United States on the editorial board, and Robinson representing Britain. The 1120 page book was p…
1950
#3788.1
Triethylene melamine in the treatment of Hodgkin’s disease and allied neoplasms
With D. A. Karnofsky, J. H. Burchenal, and L. F. Craver.
1951
#6846
The structure of proteins: Two hydrogen-bonded configurations of the polypeptide chain.
Pauling, his crystallographer R. B. Corey, and African-American physicist and chemist H.R. Branson announced the α-helix, a principal structural feature of proteins. Digital facsimile from the National Academy of Scie…
1951
#13723
Protein measurement with the Folin phenol reagent.
The Lowry protein assay, a biochemical assay for determining the total level of protein in a solution. As of 2015 this paper was considered the most highly-cited paper in the scientific literature with over 310,000 ci…
1952
#3108.2
Studies on condensed pyrimidine system. IX. The synthesis of some 6-substituted purines.
Synthesis of 6-mercaptopurine. In 1988 Gertrude Elion shared the Nobel Prize in Physiology or Medicine with George Hitchings and Sir James Black “for their discoveries of important principles for drug treatment.”
1953
#1175.3
The synthesis of an octapeptide amide with the hormonal activity of oxytocin.
Synthesis of oxytocin. With C. Ressler, J. M. Swan, C. W. Roberts, P. G. Katsoyannis, and S. Gordon. In 1955 Vigneaud was awarded the Nobel Prize in Chemistry "for his work on biochemically important sulphur compounds…
1953
#7383
Production of amino acids under possible primitive earth conditions.
The Miller–Urey experiment or Miller experiment, a classic experiment investigating abiogenesis, simulated the conditions thought at the time to be present on the early Earth, and tested the chemical origin of life un…
1954 –1960
#5352.3
Annotated bibliography of filariasis and elephantiasis. 5 parts.
South Pacific Commission Technical Papers, Nos. 65, 88, 109 (and Supplement), 124, and 160.
1954 –1965
#11218
A bibliography of the works of Antoine Laurent Lavoisier, 1743-1794
Mostly written by Herbert S. Klickstein for the collector Denis Duveen.
1955
#752.3
Enzymatic synthesis of nucleic acidlike polynucleotides.
Ochoa shared the Nobel Prize with Arthur Kornberg in 1959 for their artificial synthesis of nucleic acids by means of enzymes. Order of authorship in the original publication: Ochoa, Grunberg-Manago, Ortiz. See also O…
1955
#1207
The disulphide bonds of insulin.
Sanger sequenced the amino acids of insulin, the first of any protein. His work “revealed that a protein has a definite constant, genetically determined sequence—and yet a sequence with no general rule for its assembl…
1955
#6928
The crystal structure of the hexacarboxylic acid derived from B12 and the molecular structure of the vitamin.
The final structure of vitamin B12. With J. Pickworth, J.H. Robertson, K.N. Trueblood, R.J. Prosen, J. G. White. In 1964 Hodgkin was awarded the Nobel Prize in Chemistry "for her determinations by X-ray techniques of …
1956 –1960
#86.4
Collected papers of Paul Ehrlich. Compiled and edited by F. Himmelweit. 3 vols.
Vol. I: Histology, biochemistry, and pathology, Vol. 2: Immunology and cancer research; Vol. 3: Chemotherapy. Most texts are in German. English translations are also published when available. The set includes new Engl…
1956
#752.4
Enzymic synthesis of deoxyribonucleic acid.
In 1959 Kornberg shared the Nobel Prize in Physiology or Medicine with Severo Ochoa "for their discovery of the mechanisms in the biological synthesis of ribonucleic acid and deoxyribonucleic acid." Order of authorshi…
1957
#752.5
The nature and mode of action of oxidation enzymes. Nobel Lecture, December 12, 1955. In: Festschrift Arthur Stoll, pp. 35-47.
In 1955 Theorell was awarded the Nobel Prize in Physiology or Medicine "for his discoveries relating to the nature and mode of action of oxidation enzymes."
1957
#7386
The path of carbon in photosynthesis.
Discovery of the Calvin cycle, also known as the Calvin–Benson–Bassham (CBB) cycle, or reductive pentose phosphate cycle or C3 cycle — a series of biochemical redox reactions that take place in the stroma of chloropla…
1957
#11653
A history of luminescence: From the earliest times until 1900.
A history of bioluminescence, the production and emission of light by living organisms.
1958
#752.6
Studies on polynucleotides. I. A new and general method for the chemical synthesis of the C5'-C3' intemucleotide linkage. Synthesis of deoxyribo-dinucleotides.
In 1968 Khorana shared the Nobel Prize in Physiology or Medicine with R. W. Holley and M. W. Nirenberg "for their interpretation of the genetic code and its function in protein synthesis." H. G. Khorana, T. M. Jacob, …
1958
#6911
A three-dimensional model of the myoglobin molecule obtained by x-ray analysis.
Initial paper on the first solution of the three-dimensional molecular structure of a protein. Computing the molecular structure in 3 dimensions was possible through the use of the Cambridge EDSAC stored-program elect…
1960
#11433
Catalog of the Edgar Fahs Smith memorial collection in the history of chemistry.
Catalogue of the collection formed by Smith, provost of the University of Pennsylvania. The collection was augmented by the university after its donation by Smith.
1960
#12996
Acute pulmonary edema of high altitude.
Houston described four individuals who developed "edema of the lungs" as a result of high elevation activities. "He described chest X-rays with edema and non-specific changes on EKG. Even though these cases had been t…
1960
#14240
β-Hydroxy-β-methyl-glutaryl coenzyme A reductase, cleavage and condensing enzymes in relation to cholesterol formation in rat liver.
In 1964 Feodor Lynen shared the Nobel Prize in Physiology or Medicine with Konrad Bloch “for their discoveries concerning the mechanism and regulation of the cholesterol and fatty acid metabolism.” Order of authorship…
1960
#14283
Structure of haemoglobin: A three-dimensional Fourier synthesis at 5.5-A. resolution, obtained by X-ray analysis.
Solution of the structure of hemoglobin, a protein with 10,000 atoms. This was the culmination of 30 years of research by Perutz. Order of authorship in the original paper: Perutz, Rossmann, Culis, Muirhead, Will, Nor…
1960
#14306
The sequence of the amino acid residues in performic acid-oxidized ribonuclease.
In 1959 Moore and Stein announced the first determination of the complete amino acid sequence of an enzyme, ribonuclease. In 1972 Moore and Stein shared half of the Nobel Prize in Chemistry with Christian B. Anfinsen …
1961 –1970
#8472
A history of chemistry. Vol. 1, pt 1, Vols. 2-4.
The most comprehensive history of chemistry, with many bibliographical references. Vol. 1, pt. 2 never published.
1962
#13562
Extraction, purification and properties of Aequorin, a bioluminescent protein from the luminous hydromedusan, Aequorea.
Shimomura reported the discovery of green fluorescent protein (GFP) in a single footnote in this paper that was otherwise devoted to an entirely different bioluminescent protein: photoprotein aequorin. This may be the…
1963
#2660.16
The Vinca alkaloids: a new class of oncolytic agents.
Clinical use of vinblastine (for Hodgkin’s disease and other lymphomas) and vincristine (for acute leukemias of childhood). With J. G. Armstrong, M. Gorman, and J. P. Burnett. Preliminary communication in J. Lab. clin…
1963
#14305
The genetic control of tertiary protein structure studies with mode systems.
In 1972 Anfinsen shared half of the Nobel Prize in Chemistry with Stanford Moore and William H. Stein for "for his work on ribonuclease, especially concerning the connection between the amino acid sequence and biologi…
1964
#8174
HPP-64-1 DENDRAL-64-A system for computer construction, enumeration and notation of organic molecules as three structures and cyclic graphs. Interim report to the National Aeronautics and Space Administration, December 15, (1964).
DENDRAL is considered the first expert system because it automated the decision-making process and problem-solving behavior of organic chemists. The project consisted of research on two main programs, Heuristic Dendra…
1965
#14311
Enzymatic basis for the active transport of sodium and potassium across the cell membrane.
Skou discovered that the active transport of sodium and potassium is carried out in the cell membrane by an enzyme that serves as a sodium and potassium "pump," that catalyzes ATP hydrolysis. He named the enzyme "sodi…
1967
#7466
The origin of life.
An outstanding illustrated synthesis of the topics as they stood in 1967, including Chapter 2: "Notions of the origins of life in the past," summarizing prior theories. Appendix 1 publishes the English translation of …
1968
#752.7
Cyclic AMP.
Sutherland elucidated the role of cyclic adenosine monophosphate, the second messenger mediating actions in a wide range of hormonal effects. In 1971 Sutherland was awarded the Nobel Prize in in Physiology or Medicine…
1968 –1977
#11331
Alchemy and the occult; a catalogue of books and manuscripts from the collection of Paul and Mary Mellon given to Yale University Library. Compiled by Ian MacPhail, with essays by R. P. Multhauf and Aniela Jaffé and additional notes by William McGuire. 4 vols.
1968
#13180
Justus von Liebig. Eine Bibliographie sämtlicher Veröffentlichungen mit biographischen Anmerkungen von Carlo Paolini
1968
#13935
Reconstruction of three-dimensional structures from electron micrographs.
Klug and deRosier invented methods for two-dimensional and three-dimensional digital image processing of electron microscope images. The latter method provided the theory behind the development of computed tomography …
1972
#1588.10
A history of biochemistry. 5 vols.
Forms vols. 30-34 of Comprehensive biochemistry, edited by M. Florkin and E. H. Stotz.
1972
#1588.11
Machina carnis: the biochemistry of muscular contraction in its historical development.
A definitive history of the development of knowledge on muscle biochemistry; valuable bibliography.
1972
#257.3
Biochemical method for inserting new genetic information into DNA of simian virus 40: Circular SV40 DNA molecules containing Lambda phage genes and the galactose operon of Escherichia coli.
First recombinant DNA molecules generated. Digital facsimile from PubMedCentral at this link. In 1980 Berg was awarded half of the Nobel Prize in Chemistry "for his fundamental studies of the biochemistry of nucleic a…
1972
#12443
Geschichte der Pharmazeutischen Chemie.
1972
#12526
Die Natur- und Geheimwissenschaften im Islam.(Handbuch der Orientalistik, 1. Abteilung, Ergänzungsband VI, 2).
Concerns zoology, botany, mineralogy, alchemy, astrology, magic, agriculture, the largest section being devoted to alchemy.
1973
#14241
Regulation of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase activity in human fibroblasts by lipoproteins.
Goldstein and Brown discovered that human cells have low-density lipoprotein (LDL) receptors that remove cholesterol from the blood and that when LDL receptors are not present in sufficient numbers, individuals develo…
1974
#14315
"Conformational Coupling in Biological Energy Transductions." In L. Ernster et al. (eds.), Dynamics of Energy-Transducing Membranes, pp. 289-301.
In 1997 Boyer shared the Nobel Prize in Chemistry with John Walker and Jens C. Skou “for their elucidation of the enzymatic mechanism underlying the synthesis of adenosine triphosphate (ATP).” The Nobel Prize committe…
1975
#14182
Three-dimensional model of purple membrane obtained by electron microscopy.
The invention of Cryogenic electron microscopy (cryo-EM). The novel technique was achieved by "by applying the method to tilted specimens, and using the principles put forward by De Rosier and Klug (GM - 13935), for t…
1977
#6883
DNA sequencing with chain-terminating inhibitors.
Sanger and colleagues developed methods for rapid sequencing of long sections of DNA molecules. Sanger’s method, and that developed by Gilbert and Maxam, made it possible to read the nucleotide sequence for entire gen…
1977
#6926
A new method for sequencing DNA.
The Gilbert-Maxam method for sequencing DNA. This paper is available from PNAS at this link. In 1980 Gilbert shared the 1980 Nobel Prize in Chemistry with Frederick Sanger and Paul Berg. Berg received half of the priz…