1490 AVENZOAR [IBN ZUHR (ARABIC: ابن زهر‎ ] (1092 – 1162); AVERROËS [IBN RUSHD (ARABIC: ابن رشد‎), FULL NAME ʾABŪ L-WALĪD MUḤAMMAD IBN ʾAḤMAD IBN RUŠD] (1126 – 1198); PARAVICIUS, [Paravicinus, Patavinus] (1250 – ); JACOBUS HEBRAEUS (1250 – )

Liber Teisir, sive rectificatio medicationis et regiminis. Antidotarium. Translated from Arabic into Hebrew by Jacobus Hebraeus; into Latin by Paravicius. Add: Averroes: Colliget.

This is a Latin translation from a Hebrew version dating from 1280. Avenzoar, the greatest Muslim physician of the Western Caliphate, described the itch-mite, Sarcoptes scabiei, serous pericarditis, mediastinal absces…

GMN 47 · https://historyofmedicine.com/id/8768

1818 BORDEU, Théophile de (1722 – 1776); RICHERAND, Anthelme Louis Claude Marie (1779 – 1840)

Oeuvres complètes de Bordeu, précédés d'une notice sur sa vie et sur ses ouvrages, par M. le Chevalier Richerand. 2 vols.

GMN 10069 · https://historyofmedicine.com/id/12258

1878 SQUIRE, Alexander John Balmanno (1836 – 1908)

On the treatment of psoriasis by an ointment of chrysophanic acid.

Introduction of chrysarobin in dermatology.

GMN 4075.1 · https://historyofmedicine.com/id/5512

1886 UNNA, Paul Gerson (1850 – 1929)

Ichthyol und Resorcin als Repräsentanten der Gruppe reduzierender Heilmittel.

Unna introduced ichthyol and resorcinol into medicine. Supplement to Mh. prakt. Derm., No. 1.

GMN 1883 · https://historyofmedicine.com/id/2528

1894 CALMETTE, Léon Charles Albert (1863 – 1933)

Contribution à l’étude du vénin des serpents.

Calmette carried out extensive investigations on the immunization of animals to venoms. He obtained antivenom sera with therapeutic properties.

GMN 2107 · https://historyofmedicine.com/id/2609

1895 FRASER, Sir Thomas Richard (1841 – 1919)

On the rendering of animals immune against the venom of the cobra and other serpents; and on the antidotal properties of the blood serum of the immunised animals.

Fraser investigated the possibilities of immunization against cobra venom and obtained “antivenene”, an antivenom serum.

GMN 2108 · https://historyofmedicine.com/id/2610

1897 FREUND, Leopold (1868 – 1944)

Demonstration eines mit Röntgenstrahlen behandelten Falles von Naevus pigmentosus pilosus.

First use of x rays for deep irradiation therapy.

GMN 2002 · https://historyofmedicine.com/id/1909

1902 RICHET, Charles Robert (1850 – 1935); PORTIER, Paul (1866 – 1962)

De l’action anaphylactique de certains venins.

First full description of the phenomenon of “anaphylaxis,” the name of which was coined by Richet. Abbreviated English translation in Bibel, Milestones of immunology (1988). In 1913, Richet was awarded the Nobel Prize…

GMN 2590 · https://historyofmedicine.com/id/4397

1903 KYES, Preston (1875 – 1949); SACHS, Hans (1877 – 1945)

Zur Kenntniss der Cobragift activirenden Substanzen.

English translation in Ehrlich, Studies in immunity, 1910.

GMN 2112 · https://historyofmedicine.com/id/2617

1903 KYES, Preston (1875 – 1949)

Ueber die Isolirung von Schlangengift-Lecithiden.

English translation in Ehrlich, Studies in immunity, 1910.

GMN 2113 · https://historyofmedicine.com/id/2618

1904 POWER, Frederick Belding (1853 – 1927); GORNALL, Frank Howorth

The constituents of chaulmoogra seeds.

Hydnocarpus wightiana or Chaulmoogra is a tree in the Achariaceae family. The oil from seeds of Hydnocarpus wightiana or Chaulmoogra, a tree in the Achariaceae family, was widely used in Indian medicine and Chinese tr…

GMN 2437 · https://historyofmedicine.com/id/2907

1926 LEVADITI, Constantin (1874 – 1953)

Essai de prophylaxie des trypanosomiases par des dérivés phénylarsiniques administré

First attempt to induce prophylaxis by chemical means in trypanosomiasis. With S. Nicolau and I. Galloway.

GMN 5289 · https://historyofmedicine.com/id/6371

1929 –1934 TRENDELENBURG, Paul (1884 – 1931)

Die Hormone; ihre Physiologie und Pharmakologie. 2 vols.

GMN 1125 · https://historyofmedicine.com/id/1245

1929 SULZBERGER, Marion Baldur (1895 – 1983)

Hypersensitiveness to arsphenamine in guinea pigs. I. Experiments in prevention and desensitization.

First demonstration of specific, acquired, lasting refractoriness to sensitization. This is the same or a closely related phenomenon to that demonstrated later by Burnet and Medawar under the name immune tolerance. Se…

GMN 2576.02 · https://historyofmedicine.com/id/3707

1936 –1939 VAN DYKE, Harry Benjamin (1895 – 1971)

The physiology and pharmacology of the pituitary body. 2 vols.

Includes an extensive bibliography.

GMN 1172 · https://historyofmedicine.com/id/1574

1937 BOVET, Daniel (1907 – 1992); STAUB, Anne-Marie (1914 – 2012)

Action protectrice des éthers phénoliques au cours de l’intoxication histaminique.

First description of structure and action of an antihistamine. In 1957 Bovet was awarded the Nobel Prize in Physiology or Medicine “for his discoveries relating to synthetic compounds that inhibit the action of certai…

GMN 1925 · https://historyofmedicine.com/id/2718

1949 JONES, Reuben G.

Imidazoles. IV. The synthesis and antithyroid activity of some 1-substituted-2-mercaptoimidazoles.

Synthesis of methimazole (mercazole, thiamazole), an antithyroid drug more potent than methylthiouracil. With E. C. Kornfeld, K. C. McLaughlin, and R. C. Anderson.

GMN 3855.1 · https://historyofmedicine.com/id/4894

1956 –1960 EHRLICH, Paul (1854 – 1915); HIMMELWEIT, Fred (1902 – 1977)

Collected papers of Paul Ehrlich. Compiled and edited by F. Himmelweit. 3 vols.

Vol. I: Histology, biochemistry, and pathology, Vol. 2: Immunology and cancer research; Vol. 3: Chemotherapy. Most texts are in German. English translations are also published when available. The set includes new Engl…

GMN 86.4 · https://historyofmedicine.com/id/1453

1958 GENTLES, James Clark (1921 – 1987)

Experimental ringworm in guinea pigs: oral treatment with griseofulvin.

Use of griseofulvin in the treatment of ringworm.

GMN 4011.1 · https://historyofmedicine.com/id/5165

1971 VANE, Sir John Robert (1927 – 2004)

Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs.

In 1982 Vane shared the Nobel Prize in Physiology or Medicine with Sune Bergström and Bengt Samuelsson for "their discoveries concerning prostaglandins and related biologically active substances."

GMN 13958 · https://historyofmedicine.com/id/16259

1975 KÖHLER, Georges Jean Franz (1946 – 1995); MILSTEIN, César (1927 – 2002)

Continuous cultures of fused cells secreting antibody of predefined specificity.

Hybridomas. In 1984 Köhler and Milstein shared the Nobel Prize in Physiology or Medicine with Niels K. Jerne, "for theories concerning the specificity in development and control of the immune system and the discovery …

GMN 2578.43 · https://historyofmedicine.com/id/4314

2003 KALTER, Harold (1924 – 2019)

Teratology in the twentieth century: Congenital malformations in humans and how their environmental causes were established.

Book form publication with extensive bibliography and index, reprinted from Neurotoxicology and Teratology, 25 (2003) 132-282.

GMN 7873 · https://historyofmedicine.com/id/10045

2019 ZIMMERMANN, Michael B.; SIMMERMAN-KOGADEEVA, Maria; WEGMANN, Rebekka; ET AL

Mapping human microbiome drug metabolism by gut bacteria and their genes.

Order of authorship in the original publication: Zimmermann, Simmerman-Kogadeeva, Wegmann....The authors looked at 271 drugs and 68 different species from the main taxonomic microbiome groups. Of the 271 drugs, 176 un…

GMN 11482 · https://historyofmedicine.com/id/13681