First English book on sweating sickness, and the first devoted to a single disease to be published in England. Caius’s work appeared a year after the last epidemic visit of the disease. From it we learn that the disease was febrile, the sweating merely a manifestation of the fever, and that it was accompanied by pain in the limbs, nausea, vomiting, and delirium. A facsimile edition of the book was published in New York, 1937; it also appears in Gruner (No. 5524) and in the 1844, 1846, and 1859 editions of No. 1678.