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1,008 entries match Immunology & Dermatology [C19 / C20 / C17]
1957
#2578.22
Virus interference. I. The interferon.
Discovery of interferon type I, a protein that interferes with viral replication. "While working together at the NIMR, Lindenmann and Isaacs noticed that if they killed viruses using heat and applied the dead viruses …
1957
#2578.23
Leukocyte agglutinins in human sera. Correlations between blood transfusions and their development.
Leucocyte typing.
1957
#4154.5
Alopecia mucinosa. Inflammatory plaques with alopecia characterized by root-sheath mucinosis.
Follicular mucinosis.
1957
#13471
Chronic thyroiditis and autoimmunization.
"Witebsky helped develop procedures for the isolation and partial characterization of A and B blood antigens. He also began the practice of neutralization of certain antibodies in the blood of universal blood donors. …
1958
#2578.24
The homograft reaction.
Medawar showed grafting to be unsuccessful when donor and recipient animals came from the same litter, unless the two are genetically identical – another instance of the delayed hypersensitivity reaction.
1958
#2578.25
Separation and isolation of fractions of rabbit gamma-globulin containing the antibody and antigenic combining sites.
In 1972 Porter shared the Nobel Prize in Physiology or Medicine with G.M. Edelman (No. 2578.39) "for their discoveries concerning the chemical structure of antibodies."
1958
#2578.26
Iso-leuco-anticorps.
Discovery of the first histocompatibility antigen. In 1980 Dausset shared the Nobel Prize in Physiology or Medicine with B. Benacerraf and G. D. Snell "for their discoveries concerning genetically determined structure…
1958
#2578.27
Leucocyte antibodies in sera from pregnant women.
Leucocyte typing and matching of histocompatibility determinants. See also Payne (No. 2578.23). With J. G. Eernisse and A. van Leeuwen
1958
#2578.30
Histocompatibility genes of the mouse.
Snell made fundamental contributions to transplantation genetics. At his suggestion genes governing transplantation were called histocompatibility genes and Gorer’s Antigen II became Histocompatibility-2 (H-2). In 198…
1958
#4011.1
Experimental ringworm in guinea pigs: oral treatment with griseofulvin.
Use of griseofulvin in the treatment of ringworm.
1958
#4154.6
A unique case of trichorrhexis nodosa – “bamboo hairs”.
“Netherton’s syndrome”.
1959
#2578.31
The clonal selection theory of acquired immunity. The Abraham Flexner Lectures of Vanderbilt University 1958.
Burnet's clonal selection theory extended the idea that each antibody-producing cell makes antibodies of only one specificity, predicting these cells proliferate in response to the detection of antigens, cloning and t…
1959
#13526
Quantitative studies of tissue transplantation immunity. IV. Induction of tolerance in newborn mice and studies on the phenomenon of Runt Disease.
First description of what became known as Graft-versus-host disease (GvDH). This the authors initially called "graft against host (GAH)." The authors cited three conditions, later known as the Billingham criteria, whi…
1960
#2578.28
Immunosassay of endogenous plasma insulin in man.
First radioimmunoassay of a hormone, a test capable of estimating nonogram or even picogram quantities. In 1977 Yalow received half of the Nobel Prize in Physiology or Medicine "for the development of radioimmunoassay…
1960
#5449.4
Studies on an attenuated measles-virus vaccine. I. Development and preparation of the vaccine: technics for assay of effects of vaccination.
Live virus vaccine. With M. V. Milovanovič, and A. Holloway.
1960
#7878
Surgical diseases of the pancreas.
The first comprehensive textbook on pancreatic disease.
1960
#11219
A bibliography of internal medicine: Selected diseases.
Literature on "selected diseases" presented in chronological order, beginning with auricular fibrillation and ending with trichinosis, emphasizing cardiovascular and metabolic diseases.
1961
#2578.32
Immunological function of the thymus.
Miller demonstrated the immunological function of the thymus.
1961
#4154.7
Isolation of Blastomyces dermatitidis from soil.
With E.S. McDonough, L. Ajello and R.J. Ausherman.
1962
#1138.2
Evidence for calcitonin – a new hormone from the parathyroid that lowers blood calcium.
With E. C. Cameron, B. A. Cheney, A. G. F. Davidson, and K. G. Henze.
1962
#1931.4
The structure of prostaglandin E, F1 and F2.
In this and subsequent papers Bergström and Samuelsson elucidated the chemical structure of prostaglandins. In 1982 the Nobel Prize in Physiology or Medicine was awarded jointly to Sune K. Bergström, Bengt I. Samuelss…
1962
#2578.33
Initiation of immune responses by small lymphocytes.
Gowans and colleagues showed that the lymphocyte is the immunologically competent cell.
1962
#12033
Host specificity of DNA produced by escherichia coli. II. Control over acceptance of DNA from infecting phage lambda.
Order of authorship in the original publication: Dussoix, Arber. The authors discovered that restriction of DNA from infecting bacteriophage was due to the attack and breakdown of the modified bacteriophage's DNA by s…
1963 –1964
#534.9
Studien zur Historik der Teratologie.
1963
#2578.34
Plaque formation in agar by single antibody-producing cells.
Hemolytic plaque assay for enumerating antibody-forming cells.
1963
#2578.35
Individual antigenic specificity of isolated antibodies.
Idiotypes. With M. Mannik and R.C. Williams. Kunkel and his team discovered idiotypy independently of Jacques Oudin and Philip Gell.
1963
#3924.4
A simple phenylalanine method for detecting phenylketonuria in large populations of newborn infants.
Bacterial inhibition test for phenylketonuria.
1963
#5308.2
On the origin of the human treponematoses (pinta, yaws, endemic syphilis and venereal syphilis).
“Perhaps the most scholarly investigation of the origin of syphilis” (Wesley Spink).
1963
#6495.8
The medical writings of Moses Maimonides. Treatise on asthma.
1963
#6941
Effect of the laser beam on the skin.
One of the first papers on the application of lasers in medicine. In 1961 Goldman became the first researcher to use a laser to treat a human skin disease when he treated melanoma. The method later became popular in r…
1963
#8398
Clinical aspects of immunology.
Gell-Coombs classification of hypersensitivity. Prior to development of this classification, all forms of hypersensitivity were classified as allergies, "and all were thought to be caused by an improper activation of …
1964
#14197
A familial disorder of uric acid metabolism and central nervous system dysfunction.
Lesch-Nyhan syndrome, a rare inherited disorder that affects about 1 in 380,000 live births. In their summary the authors described this as a new "syndrome consisting of hyperuricemia, mental retardation, choreoatheto…
1965
#1207.1
Total synthesis of crystalline bovine insulin.
1965
#2581.6
A history of immunization.
1965
#3666.4
A “new” antigen in leukemia sera.
(Order of authorship in the original publication: Blumberg, Alter, Visnich.) Discovery of Australia antigen, hepatitis B antigen, Aa, later called HBsAg. Blumberg received half of the Nobel Prize for Medicine in Biolo…
1965
#4154.8
Genetic classification of ichthyosis.
Sex-linked recessive ichthyosis shown to be an important but not uncommon entity. See also Kerr & Wells: Sex-linked ichthyosis. Ann. hum. Genet., 1965, 29, 33-50.
1966
#2578.36
Delayed hypersensitivity in vitro: its mediation by cell-free substances formed by lymphoid cell-antigen interaction.
Lymphokines (MIF). Simultanteously discovered by Barry R. Bloom (1937-) & B. Bennett. See Science, 1966, 153, 80-82.
1966
#2578.37
Thymus-marrow cell combinations, Synergism in antibody production.
T cell subsets. With R.F. Triplett.
1966
#5509.3
Attenuated rubella virus. II. Production of an experimental live-virus vaccine and clinical trial.
With T. C. Panos.
1966
#8399
Physico-chemical properties of human reaginic antibody. IV. Presence of a unique immunoglobulin as a carrier of reaginic activity.
The antibody class labeled immunoglobulin E (IgE) discovered simultanteously by two independent groups: Ishizaka's team at the Children's Asthma Research Institute and Hospital in Denver, Colorado, and by Gunnar Johan…
1967
#14198
Enzyme defect associated with a sex-linked human neurological disorder and excessive purine synthesis.
Jay Seegmiller and his colleagues at NIH discovered that the rare genetic disease, Lesch–Nyhan syndrome, was due to a profound deficiency of an enzyme known as hypoxanthine guanine phosphoribosyltransferase, or HGPRT.…
1968
#2578.38
The H-2 locus of the mouse: observations and speculations concerning its comparative genetics and its polymorphism.
Antigen II, discovered by Gorer (No. 2576.5), was studied by Snell and became known as the product of the H-2 locus, the fundamental locus in the history of mammalian transplant biology.
1968
#12028
Host specificity of DNA produced by Escherichia coli, X. In vitro restriction of phage FD replicative form.
Order of authorship in the original publication: Linn, Arber. Arber announced the discovery, with proof, of the first restriction endonuclease (restriction enzyme or restrictase)."These enzymes are found in bacteria a…
1968
#12038
Correspondence of Pasteur & Thuillier concerning anthrax and swine fever vaccinations. Translated and edited by Robert M. Frank and Denise Wrotnowska. Preface by Louis Pasteur Vallery-Radot.
Edition and translation of about 60 letters mostly between Pasteur and his protegé Louis Thuillier in the Reynolds Historical Library at the University of Alabama. During the period involved in this correspondence "Th…
1969
#2578.39
The covalent structure of an entire ÁG immunoglobulin molecule.
Complete sequence of an immunoglobulin molecule. With five coauthors. In 1972 Edelman shared the Nobel Prize in Physiology or Medicine with R. R. Porter “for their discoveries concerning the chemical structure of anti…
1969
#5440.2
Prevention of varicella by zoster immune globulin.
With A. Ross, L. H. Miller, and B. Kuo.
1969 –1972
#6841
Vaccine against viral hepatitis and process. Serial No. 864,788 filed 10 /8 /[19]69. Patent 3636191 issued 1/ 18/ [19]72.
First description of the hepatitis B vaccine, the first cancer vaccine, US patent 3636191A. Millman and Blumberg discovered that the blood of individuals carrying the hepatitis B virus contained particles of the outsi…
1970
#2660.26
Field trials with an attentuated cell associated vaccine for Marek's disease.
In 1959 Biggs moved to the Houghton Poultry Research Station (HPRS) to form and head a unit to study lymphoid tumor conditions of the domestic fowl. He gave the name Marek’s disease to one of the tumor conditions, aft…
1970
#2578.40
An analysis of the sequences of the variable regions of Bence Jones proteins and myeloma light chains and their implications for antibody complementarity.
Hypervariable regions of “Ig.”
1970
#2578.41
Cell interactions in the induction of tolerance: The role of thymic lymphocytes.
Suppressor T cells.