An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2024 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

16061 entries, 14144 authors and 1947 subjects. Updated: December 10, 2024

Permanent Link for Entry #16567

  • 14248

Nitric oxide activates guanylate cyclase and increases guanosine 3',5'-monophosphate levels in various tissue preparations.

Proc. Nat. Acad. Sci. (U.S.A.), 74, 3203-3207, 1977.

Murad demonstrated that nitroglycerin and related drugs worked by releasing nitric oxide into the body, which relaxed smooth muscle by elevating intracellular cyclic GMP. With W. P. Arnold, C. K. Mittal, S. Katsuki.

In 1998 the Nobel Prize in Physiology of Medicine was awarded jointly to Robert F. Furchgott, Louis J. Ignarro and Ferid Murad "for their discoveries concerning nitric oxide as a signalling molecule in the cardiovascular system."



Subjects: CARDIOLOGY › CARDIOVASCULAR PHYSIOLOGY, NOBEL PRIZES › Nobel Prize in Physiology or Medicine
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