An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2024 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

16061 entries, 14144 authors and 1947 subjects. Updated: December 10, 2024

Permanent Link for Entry #894

  • 4672.3

Immunization of chimpanzees and human beings with avirulent strains of poliomyelitis virus.

Ann. N. Y. Acad. Sci., 61, 1050-1056, 1955.

Sabin reported the successful immunization of chimpanzees by oral and I.M. route using the Brunhilde, Mahoney and Leon strains of polio virus. On p. 1055 he reported the experimental results on humans given a "single feeding" of avirulent (attenuated) virus. This was his first report on the success of the Sabin attenuated poliomyelitis oral vaccine.

(Thanks to Juan Weiss for this reference and its interpretation.)



Subjects: IMMUNOLOGY › Immunization, IMMUNOLOGY › Vaccines, INFECTIOUS DISEASE › Neuroinfectious Diseases › Poliomyelitis (Infantile Paralysis), NEUROLOGY › Inflammatory Conditions › Poliomyelitis, VIROLOGY › VIRUSES (by Family) › Picornaviridae › Poliovirus
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