1909 LANDSTEINER, Karl (1868 – 1943); POPPER, Erwin (1879 – 1955)
Uebertragung der Poliomyelitis acuta auf Affen.
Landsteiner and Popper were the first to isolate poliovirus and to transmit poliomyelitis to monkeys.
GMN 4669 · https://historyofmedicine.com/id/830
1910 LANDSTEINER, Karl (1868 – 1943); LEVADITI, Constantin (1874 – 1953)
La poliomyélite experimental.
Serum from a monkey that had recovered from experimental poliomyelitis was mixed with an emulsion containing active polio virus; it failed to produce paralytic disease when injected into fresh monkeys.
GMN 4670.3 · https://historyofmedicine.com/id/853
1912 KLING, Carl (1887 – 1967)
Experimental and pathological investigation. In: Investigations on epidemic infantile paralysis, report from the State Medical Institute of Sweden to the XVth International Congress on Hygiene and Demography.
Kling, A. Pettersson, and W. Wernstedt recovered the poliomyelitis virus from the intestinal wall and contents, disproving the contention of Flexner that it was exclusively neurotropic.
GMN 4670.4 · https://historyofmedicine.com/id/857
1931 BURNET, Sir Frank Macfarlane (1899 – 1985); MACNAMARA, Annie Jean Dame (1899 – 1968)
Immunological differences between strains of poliomyelitis virus.
GMN 4670.5 · https://historyofmedicine.com/id/861
1936 SABIN, Albert Bruce (1906 – 1993); OLITSKY, Peter Kosciusko (1886 – 1964)
Cultivation of poliomyelitis virus in vitro in human embryonic nervous tissue.
Isolation and propagation of the poliomyelitis virus in pure culture.
GMN 4670.6 · https://historyofmedicine.com/id/868
1939 ARMSTRONG, Charles (1886 – 1967)
Successful transfer of the Lansing strain of poliomyelitis virus from the cotton rat to the white mouse.
Armstrong adapted the Lansing strain of poliomyelitis to the cotton rat and then to the mouse, greatly facilitating experimental work on the disease.
GMN 4671.2 · https://historyofmedicine.com/id/878
1949 ENDERS, John Franklin (1897 – 1985); WELLER, Thomas Huckle (1915 – 2008); ROBBINS, Frederick Chapman (1916 – 2003)
Cultivation of the Lansing strain of poliomyelitis virus in cultures of various human embryonic tissues.
Enders, Weller, and Robbins grew the poliomyelitis virus in cultures of different tissues. Their method proved of great value in virus research, and removed the final obstacles to vaccine production. In 1974 Enders, W…
GMN 4671.1 · https://historyofmedicine.com/id/874
1952 KOPROWSKI, Hilary (1916 – 2013); ET AL
Immune responses in human volunteers upon oral administration of a rodent-adapted strain of poliomyelitis virus.
Successful immunization against poliomyelitis with a living attenuated virus vaccine. With G. A. Jervis and T. W. Norton.
GMN 4672.1 · https://historyofmedicine.com/id/885
1952 ENDERS, John Franklin (1897 – 1985); WELLER, Thomas Huckle (1915 – 2008); ROBBINS, Frederick Chapman (1916 – 2003); ET AL
Studies on the cultivation of poliomyelitis viruses in tissue culture.
Order of authorship in the original publication: Weller, Enders, Robbins. In this paper the authors describe their improved method for culturing poliomyelitis viruses in "normal kidney tissue." Followed by Robbins, We…
GMN 11103 · https://historyofmedicine.com/id/13299
1953 SALK, Jonas Edward (1914 – 1995); ET AL
Studies in human subjects on active immunization against poliomyelitis. 1. A preliminary report of experiments in progress.
Killed-virus vaccine. With four co-authors.
GMN 4672.2 · https://historyofmedicine.com/id/889
1954 VOGT, Marguerite (1913 – 2007); DULBECCO, Renato (1914 – 2012)
Plaque formation and isolation of pure lines with poliomyelitis viruses.
Dulbecco and Vogt were the first to successfully grow the poliovirus in vitro. They were also able to plaque purify it-- an essential step for subsequent vaccine production.
GMN 14000 · https://historyofmedicine.com/id/16304
1955 SABIN, Albert Bruce (1906 – 1993)
Immunization of chimpanzees and human beings with avirulent strains of poliomyelitis virus.
Sabin reported the successful immunization of chimpanzees by oral and I.M. route using the Brunhilde, Mahoney and Leon strains of polio virus. On p. 1055 he reported the experimental results on humans given a "single …
GMN 4672.3 · https://historyofmedicine.com/id/894
1981 BALTIMORE, David (1938 – ); RACANIELLO, Vincent R. (1953 – )
Molecular cloning of poliovirus cDNA and determination of the complete nucleotide sequence of the viral genome.
The poliovirus genome. Digital facsimile from PNAS through PubMedCentral at this link.
GMN 9175 · https://historyofmedicine.com/id/11354
2013 WILLIAMS, Gareth
Paralysed with fear: The story of polio.
GMN 10219 · https://historyofmedicine.com/id/12409
