1685 BROWNE, John (1642 – 1702)
A remarkable account of a liver, appearing glandulous to the eye.
First description of cirrhosis of the liver.
GMN 3613 · https://historyofmedicine.com/id/4538
1819 LAENNEC, René Théophile Hyacinthe (1781 – 1826)
De l’auscultation médiate, ou traité du diagnostic des maladies des poumons et du coeur. 2 vols.
This book revolutionized the study of diseases of the chest. Auscultation in the instrumental sense dates from Laennec’s invention of the stethoscope (at first merely a roll of stiff paper) with a view to amplifying t…
GMN 2673 · https://historyofmedicine.com/id/3518
1833 STANLEY, Edward (1793 – 1862)
Abscess of the liver, with hydatids. – Operation.
Diagnostic liver puncture.
GMN 3616 · https://historyofmedicine.com/id/4548
1836 BRIGHT, Richard (1789 – 1858)
Observations on jaundice.
Original description of acute yellow atrophy of the liver.
GMN 3617 · https://historyofmedicine.com/id/4551
1842 –1846 ROKITANSKY, Carl Freiherr von (1804 – 1878)
Handbuch der pathologischen Anatomie. 3 vols.
Rokitansky ranks with Morgagni as among the greatest of all writers on gross pathology. He is said to have performed over 30,000 autopsies himself. His Handbuch was for many years pre-eminent among its contemporaries.…
GMN 2293 · https://historyofmedicine.com/id/2924
1845 BUDD, George (1808 – 1882)
On diseases of the liver.
Budd was Professor of Medicine at King’s College, London. Section III of the above book includes a description of that form of cirrhosis to which the name “Budd’s disease” has been applied. In the second edition, 1852…
GMN 3619 · https://historyofmedicine.com/id/4559
1856 JIMÉNEZ, Miguel Francisco (1813 – 1876)
Clinica médica. Abcesos del higado.
Jimenez gave a classic account of liver abscess in amoebiasis.
GMN 5183.2 · https://historyofmedicine.com/id/6317
1856 ARETAEUS OF CAPPADOCIA, (Ἀρεταῖος Καππάδοκος) (80 – 140); ADAMS, Francis (1796 – 1861)
Тα ∑ωζομενα. The extant works of Aretaeus, the Cappadocian. Edited and translated by Francis Adams.
Aretaeus left many fine descriptions of disease; in fact Garrison ranks him second only to Hippocrates in this respect. In the printed editions of this bibliography, before the present online version, the Adams editio…
GMN 22 · https://historyofmedicine.com/id/8934
1858 –1861 FRERICHS, Friedrich Theodor von (1819 – 1885)
Klinik der Leberkrankheiten. 2 vols. and atlas.
Frerichs’s classic monograph on diseases of the liver summarized the existing knowledge and included his own important work on the subject. He discovered leucine and tyrosine in the liver in acute yellow atrophy (Dtsc…
GMN 3620 · https://historyofmedicine.com/id/4561
1868 MURCHISON, Charles (1830 – 1879)
Clinical lectures on diseases of the liver.
GMN 3622 · https://historyofmedicine.com/id/4566
1874 HAYEM, Georges (1841 – 1933)
Contribution à l’étude de l’hépatite interstitielle chronique avec hypertrophie (sclérose ou cirrhose hypertrophique du foie).
Classic description of chronic interstitial hepatitis.
GMN 3623 · https://historyofmedicine.com/id/4568
1875 MCCONNELL, James Frederick Parry (1848 – 1896)
Remarks on the anatomy and pathological relations of a new species of liver fluke.
First complete description of Chlonorchis sinensis.
GMN 5344.9 · https://historyofmedicine.com/id/6786
1876 HANOT, Victor Charles (1844 – 1896)
Étude sur une forme de cirrhose hypertrophique du foie (cirrhose hypertrophique avec ictère chronique).
“Hanot’s disease”. First description of hypertrophic cirrhosis of the liver with icterus. Thesis publication, 1875; published in book form, Paris, 1876. Digital facsimile of the book form edition from the Internet Arc…
GMN 3624 · https://historyofmedicine.com/id/4571
1877 ECK, Nikolai Vladimirovich (1848 – 1908)
K voprosu o perevyazkie vorotnoi veni. Predvaritelnoye soobshtshenize. [On the ligature of the portal vein.]
Eck developed the “Eck fistula” for the experimental study of diseases of the liver and the relation of the liver to metabolism. English translation in Surg. Gynec. Obstet., 1953, 96, 375.
GMN 630 · https://historyofmedicine.com/id/586
1878 SIMS, James Marion (1813 – 1883)
Remarks on cholecystotomy in dropsy of the gall-bladder.
Sims’ operation of cholecystotomy.
GMN 3625 · https://historyofmedicine.com/id/4573
1888 RIEDEL, Bernhard Moritz Carl Ludwig (1846 – 1916)
Ueber den zungenförmigen Fortsatz des rechten Leberlappens und seine pathognostiche Bedeutung für die Erkrankung der Gallenblase nebst Bemerkungen über Gallensteinoperationen.
“Riedel’s lobe”, a form of constriction lobe of the liver.
GMN 3631 · https://historyofmedicine.com/id/4614
1895 LUCATELLO, Luigi (1863 – 1926)
Sulla puntura del fegato a scopo diagnostico.
Liver puncture biopsy.
GMN 3635 · https://historyofmedicine.com/id/4632
1896 PICK, Friedel (1867 – 1926)
Ueber chronische unter dem Bilde der Leberzirrhose verlaufende Perikarditis (perikarditische Pseudoleberzirrhose) nebst Bemerkungen über die Zuckergussleber.
“Pick’s disease” – pericardial pseudocirrhosis of the liver.
GMN 2803 · https://historyofmedicine.com/id/3431
1898 BOBROV, Alexander Alexievich (1850 – 1904)
Ueber ein neues Operationsverfahren zur Entfernung von Echinococcus in der Leber und anderen parenchymatösen Bauchorganen.
Important work on surgical treatment of hydatids of the liver. Originally appeared in Russian in Khirurgiya, 1898, 3, 3-9.
GMN 3637 · https://historyofmedicine.com/id/4635
1898 TALMA, Sape (1847 – 1918)
Chirurgische Oeffnung neuer Seitenbahnen für das Blut der Vena portae.
Talma’s operation for the relief of ascites in cirrhosis of the liver.
GMN 3639 · https://historyofmedicine.com/id/4638
1900 –1901 HEKTOEN, Ludvig (1863 – 1951)
Experimental bacillary cirrhosis of the liver.
Hektoen produced experimental cirrhosis of the liver. His notable work in pathology includes the foundation of the Archives of Pathology.
GMN 3640 · https://historyofmedicine.com/id/4650
1904 KATSURADA, Fujiro (1867 – 1946)
The aetiology of a parasitic disease (in Japanese)
First description of Schistosoma japonicum. Translation in Kean (No. 2368.1), p. 518.
GMN 5349.1 · https://historyofmedicine.com/id/6829
1906 DARLING, Samuel Taylor (1872 – 1925)
A protozoon general infection producing pseudotubercles in the lungs and focal necroses in the liver, spleen and lymphnodes.
Histoplasmosis (Histoplasma capsulatum), “Darling’s disease”.
GMN 5532 · https://historyofmedicine.com/id/6676
1912 ROGERS, Sir Leonard (1868 – 1962)
The rapid cure of amoebic dysentery and hepatitis by hypodermic injections of soluble salts of emetine.
Following up the work of Vedder, Rogers showed that the soluble salts of emetine could be safely injected subcutaneously. The general use of emetine, introduced by Rogers, diminished the incidence of liver abscess – a…
GMN 5190 · https://historyofmedicine.com/id/7047
1925 TAKATA, Maki (1892 – 1978); ARA, Kiyoshi (1894 – )
Ueber eine neue kolloidchemische Liquorreaktion und ihre praktischen Ergebnisse.
Takata-Ara reaction for the diagnosis of liver disease.
GMN 3654 · https://historyofmedicine.com/id/4759
1929 GIERKE, Edgar Otto Konrad von (1877 – 1945)
Hepato-nephromegalia glykogenika (Glykogenspeicherkrankheit der Leber und Nieren).
“Von Gierke’s disease”, glycogen disease of hepatomegalic type. See also the review by S. van Creveld, Medicine, 1939, 18, 1-128.
GMN 3656 · https://historyofmedicine.com/id/4767
1929 ROLLESTON, Sir Humphrey Davy (1862 – 1944); MCNEE, Sir John William (1887 – 1984)
Diseases of the liver, gall-bladder, and bile ducts. 3rd edition.
GMN 3657 · https://historyofmedicine.com/id/4771
1937 PATEK, Arthur Jackson Jr. (1904 – 1991)
Treatment of alcoholic cirrhosis of the liver with high vitamin therapy.
A pioneer paper on the dietary treatment of cirrhosis.
GMN 3661 · https://historyofmedicine.com/id/4808
1939 IVERSON, Poul (1889 – ); ROHOLM, Kaj (1902 – 1948)
On aspiration biopsy of the liver, with remarks on its diagnostic significance.
Modern method of liver puncture.
GMN 3664 · https://historyofmedicine.com/id/4812
1942 VOEGT, H
Zur Aetiologie der Hepatitis epidemica.
Transmission of infective hepatitis agent.
GMN 3664.1 · https://historyofmedicine.com/id/4813
1944 MACCALLUM, Frederick Ogden; BRADLEY, W. H.
Transmission of infective hepatitis to human volunteers.
MacCallum and Bradley finally proved the nature of both serum and infective hepatitis.
GMN 3664.2 · https://historyofmedicine.com/id/4815
1944 MACCALLUM, Frederick Ogden; BAUER, Denis John (1914 – 2001)
Homologous serum jaundice. Transmission experiments with human volunteers.
GMN 3664.3 · https://historyofmedicine.com/id/4816
1951 ABEATICI, Sergio (1922 – 2000); CAMPI, L
La visualizzazione radiologica della porta pervia splenica.
Introduction of portal venography for investigation of portal hypertension.
GMN 2725.1 · https://historyofmedicine.com/id/4463
1955 WELCH, Charles Stuart (1909 – )
A note on transplantation of the whole liver in dogs.
Placement of auxiliary whole liver.
GMN 3666.1 · https://historyofmedicine.com/id/4819
1955 SHERLOCK, Sheila Patricia Violet Dame (1918 – 2001)
Diseases of the liver and biliary system.
13th edition, 2018. "In 1959 she [Sherlock] became the United Kingdom's first ever female Professor of Medicine when she was appointed at the Royal Free Hospital School of Medicine in London. She founded the liver uni…
GMN 10994 · https://historyofmedicine.com/id/13190
1959 MOORE, Francis Daniels (1913 – 2001)
One-stage homotransplantation of the liver following total hepatectomy in dogs.
With nine co-authors.
GMN 3666.2 · https://historyofmedicine.com/id/4820
1963 STARZL, Thomas Earl (1926 – 2017)
Homotransplantation of the liver in humans.
First human liver transplant (three patients; one died during operation, the second after 7.5 days, and the third after 22 days). With five co-authors.
GMN 3666.3 · https://historyofmedicine.com/id/4821
1965 BLUMBERG, Baruch Samuel (1925 – 2011); ALTER, Harvey James (1935 – ); VISNICH, S.; ET AL
A “new” antigen in leukemia sera.
(Order of authorship in the original publication: Blumberg, Alter, Visnich.) Discovery of Australia antigen, hepatitis B antigen, Aa, later called HBsAg. Blumberg received half of the Nobel Prize for Medicine in Biolo…
GMN 3666.4 · https://historyofmedicine.com/id/4823
1967 KRUGMAN, Saul (1911 – 1995); ET AL
Infectious hepatitis. Evidence for two distinctive clinical, epidemiological, and immunological types of infection.
With J. P. Giles and J. Hammond.
GMN 3666.5 · https://historyofmedicine.com/id/4824
1969 –1972 BLUMBERG, Baruch Samuel (1925 – 2011); MILLMAN, Irving (1923 – 2012)
Vaccine against viral hepatitis and process. Serial No. 864,788 filed 10 /8 /[19]69. Patent 3636191 issued 1/ 18/ [19]72.
First description of the hepatitis B vaccine, the first cancer vaccine, US patent 3636191A. Millman and Blumberg discovered that the blood of individuals carrying the hepatitis B virus contained particles of the outsi…
GMN 6841 · https://historyofmedicine.com/id/9005
1970 SHERLOCK, Sheila Patricia Violet Dame (1918 – 2001); NIAZI, S. P.; FOX, R. A.
Chronic liver disease and primary liver-cell cancer with hepatitis-associated (Australia) antigen in serum.
(Order of authorship in the original publication: Sherlock, Niazi, Fox...). The authors demonstrated that the hepatitis B virus can cause cancer. (Thanks to Juan Weiss for this reference and its interpretation.)
GMN 12306 · https://historyofmedicine.com/id/14528