1939 WHITE, Priscilla (1900 – 1989); ET AL
Prediction and prevention of late pregnancy accidents in diabetes.
First report of hormone treatment. Written with R.S. Titus, E.P. Joslin, and H. Hunt.
GMN 6231 · https://historyofmedicine.com/id/7860
1940 EVANS, Herbert McLean (1882 – 1971); LI, Choh Hao (1913 – 1987); SIMPSON, Miriam Elizabeth (1894 – 1991)
Interstitial cell stimulating hormone. II. Method of preparation and some physico-chemical studies.
Choh Hao Li and colleagues isolated of the interstitial cell stimulating (luteinizing) hormone.
GMN 1173.1 · https://historyofmedicine.com/id/1578
1940 MCKEE, Clara M.
Complement-fixation test in lymphogranuloma venereum.
Diagnosis of lymphogranuloma venereum by complement-fixation test. With G. W. Rake and M. F. Shaffer.
GMN 5224 · https://historyofmedicine.com/id/7840
1940 MUDROW, Lilly (1908 – 1957)
Klinische und parasitologische Befunde und chemotherapeutische Ergebnisse bei der Hühnermalaria.
Discovery of the developmental forms of P. gallinaceum in the incubation period.
GMN 5259 · https://historyofmedicine.com/id/8542
1941 PANGBORN, Mary Candace (1907 – 2003)
A new serologically active phospholipid from beef heart.
Cardiolipin antigen for serological diagnosis of syphilis. For isolation and purification see J. biol. Chem., 1942, 143, 247-56.
GMN 2417 · https://historyofmedicine.com/id/3420
1941 HARE, Ronald (1899 – 1986); MCCLELLAND, Laurella (1912 – 1993)
The absorption of influenza virus by red cells and a new in vitro method of measuring antibodies for influenza virus.
Independently of Hirst, McClelland and Hare discovered virus hemagglutination.
GMN 2578 · https://historyofmedicine.com/id/4133
1942 FREUND, Jules Thomas (1891 – 1960); MCDERMOTT, Katherine
Sensitization to horse serum by means of adjuvants.
Freund’s adjuvant. Freund’s procedure allowed adjuvants to be used for any antigen.
GMN 2578.1 · https://historyofmedicine.com/id/4135
1942 FELTON, Lloyd Derr (1885 – 1953); OTTINGER, Barbara
Pneumococcus polysaccharide as a paralyzing agent on the mechanism of immunity in white mice.
GMN 2578.2 · https://historyofmedicine.com/id/4138
1942 TREADWELL, Anne de G.; ET AL
Metabolic studies on neoplasm of bone with the aid of radioactive strontium.
Radioisotopic bone scanning. With B. Low-Beer, H. Friedell, and J. Lawrence.
GMN 2700.01 · https://historyofmedicine.com/id/4324
1942 GRIFFITH, Harold Randall (1894 – 1985); MACLEOD, Enid Johnson (1909 – 2001)
The use of curare in general anesthesia.
Introduction of curare in anesthesia.
GMN 5724 · https://historyofmedicine.com/id/6458
1943 EVANS, Herbert McLean (1882 – 1971); LI, Choh Hao (1913 – 1987); SIMPSON, Miriam Elizabeth (1894 – 1991)
Adrenocorticotropic hormone.
Choh Hao Li and colleagues Isolated pure adrenocorticotropic hormone (ACTH) from sheep pituitary glands.
GMN 1174 · https://historyofmedicine.com/id/1580
1943 SANO, Machteld Elisabeth (1903 – 1993)
Skin grafting. A new method based on the principles of tissue culture.
First use of fibrin glue for skin grafting. See also Surg. Gynec. Obstet., 1943, 77, 510-13.
GMN 5765 · https://historyofmedicine.com/id/6725
1943 JENSEN, Deborah Maclurg (1900 – 1962)
History of nursing.
Second edition, History and trends of professional nursing, 1950.
GMN 6636 · https://historyofmedicine.com/id/7733
1943 HUGHES, Muriel Joy (1903 – )
Women healers in medieval life and literature.
Digital facsimile from the Hathi Trust at this link.
GMN 8554 · https://historyofmedicine.com/id/10731
1943 HAMILTON, Alice (1869 – 1970)
Exploring the dangerous trades: The autobiography of Alice Hamilton.
Digital facsimile from the Internet Archive at this link.
GMN 8590 · https://historyofmedicine.com/id/10767
1944 ROCK, John A. (1890 – 1984); MENKIN, Miriam Friedman (1901 – 1992)
In vitro ferilization and cleavage of human ovarian eggs.
First in vitro fertilization of human eggs.
GMN 532.1 · https://historyofmedicine.com/id/1698
1944 SCHATZ, Albert (1920 – 2005); WAKSMAN, Selman Abraham (1888 – 1973); GREGORY, Elizabeth Bugie
Streptomycin, a substance exhibiting antibiotic activity against Grampositive and Gram-negative bacteria.
Introduction of streptomycin. Order of authorship: Schatz, Gregory, Waksman. In 1952 Waksman was awarded the Nobel Prize in Physiology or Medicine "for ingenious, systematic, and successful studies of the soil microbe…
GMN 1935 · https://historyofmedicine.com/id/2788
1944 –1948 KEFFER, Luiza
Indice bibliográfico de lepra, 1560-1943. 3 vols.
Supplements 1-5, 1952-62.
GMN 2447 · https://historyofmedicine.com/id/2944
1944 LEUCHTENBERGER, Cecile (1906 – ); LEUCHTENBERGER, Rudolf; ET AL
“Folic acid” a tumor growth inhibitor.
Inhibition of tumor growth by a folic acid concentrate. With R. Lewisohn, D. Laszlo. These workers later (Proc. Soc. exp. Biol. N. Y., 1944, 56, 144-45) obtained similar results with xanthopterin.
GMN 2659.2 · https://historyofmedicine.com/id/3352
1945 EVANS, Herbert McLean (1882 – 1971); LI, Choh Hao (1913 – 1987); SIMPSON, Miriam Elizabeth (1894 – 1991)
Isolation and properties of the anterior hypophyseal growth hormone.
Choh Hao Li and colleagues isolated the anterior pituitary growth hormone.
GMN 1175.1 · https://historyofmedicine.com/id/1585
1945 JOHNSON, Balbina A. (1897 – 1970); ET AL
Bacitracin: a new antibiotic produced by a member of the B, subtilis group.
With H. Anker and F. L. Meleney.
GMN 1936 · https://historyofmedicine.com/id/2789
1945 BLALOCK, Alfred (1899 – 1964); TAUSSIG, Helen Brooke (1898 – 1986)
The surgical treatment of malformations of the heart in which there is pulmonary stenosis or pulmonary atresia.
The “Blalock-Taussig operation” for the relief of congenital defects of the pulmonary artery, Tetralogy of Fallot ("blue baby syndrome"). "The first surgical repair was carried out in 1944 at Johns Hopkins.[70] The pr…
GMN 3043 · https://historyofmedicine.com/id/3475
1945 ROTH, Grace M. (1894 – 1982); KVALE, Walter Frederick (1907 – 1970)
A tentative test for pheochromocytoma.
The Roth–Kvale histamine test for the diagnosis of pheochromocytoma.
GMN 3869 · https://historyofmedicine.com/id/4921
1946 PATERSON, Edith (1900 – 1995); ET AL
Leukaemia treated with urethane compared with deep x-ray therapy.
Urethane in treatment of leukemia. With A. Haddow, I. Ap Thomas, and J. M. Watkinson.
GMN 3106 · https://historyofmedicine.com/id/3811
1946 GOETSCH, Anne Carlton Tompkins (1917 – 2003); ET AL
Observations on the effect of massive doses of iron given intravenously to patients with hypochromic anemia.
GMN 3152 · https://historyofmedicine.com/id/4008
1946 PICKARD, Madge Evelyn; BULEY, Roscoe Carlyle (1893 – 1968)
The midwest pioneer: His ills, cures, & doctors.
The first general history of frontier or pioneer medicine in America, covering mainly the first half of the 19th century, and including many folk medicine treatments. First published privately in Crawfordsville, India…
GMN 8741 · https://historyofmedicine.com/id/10919
1947 SHORB, Mary Shaw (1907 – 1990)
Unidentified growth factors for Lactobacillus lactis in refined liver extract.
Mary Shorb provided a method of biological assay of liver extracts that made possible the isolation of vitamin B12.
GMN 1090 · https://historyofmedicine.com/id/869
1947 WALSH, Robert John (1917 – 1983); MONTGOMERY, Carmel M.
A new human iso-agglutinin subdividing the MN blood groups.
S blood-group antigen.
GMN 913 · https://historyofmedicine.com/id/1089
1947 TAUSSIG, Helen Brooke (1898 – 1986)
Congenital malformations of the heart.
This 618-page work, which required ten years to write, was the first "definitive textbook" of congenital heart defects, a subspecialty of pediatrics that Taussig created. The second edition, published in 1960, was ess…
GMN 2878 · https://historyofmedicine.com/id/4208
1947 METTLER, Cecilia Charlotte Asper (1909 – 1943); METTLER, Fred A.
History of medicine. A correlative text arranged according to subjects by Cecilia Mettler. Edited by Fred A Mettler.
Posthumously published after the author died three days after childbirth.
GMN 6440 · https://historyofmedicine.com/id/8433
1947 SMADEL, Joseph Edwin (1907 – 1963); JACKSON, Elizabeth B.
Chloromycetin, an antibiotic with chemotherapeutic activity in experimental rickettsial and viral infections.
Introduction of chloramphenicol, used in treatment of typhus.
GMN 1940 · https://historyofmedicine.com/id/8617
1948 SANFORD, Katherine Koontz (1915 – 2005); ET AL
The growth in vitro of single isolated tissue cells.
Sanford was the first to clone in vitro a single living cell of a mammal—in this instance, a rodent. She performed this feat in search of a means to research how cells transform into malignancy.
GMN 566.2 · https://historyofmedicine.com/id/300
1948 HARKEN, Dwight Emary (1910 – 1993); ZARSKY, Leona Norman (1923 – 2013); ET AL
The surgical treatment of mitral stenosis. 1. Valvuloplasty.
Valvuloplasty for mitral stenosis. Harken reported the first successful intracardiac operation for treatment of this lesion--a procedure was first attempted in the 1920s. Charles Bailey in Philadelphia undertook a sim…
GMN 3046.1 · https://historyofmedicine.com/id/3527
1948 SPITZ, Sophie (1910 – 1956)
Melanomas of childhood.
Spitz first defined the histologic criteria for the diagnosis of juvenile melanoma.
GMN 4154.1 · https://historyofmedicine.com/id/5874
1948 PATON, Sir William Drummond Macdonald (1917 – 1993); ZAIMIS, Eleanor (1915 – 1982)
Curare-like action of polymethylene bis-quaternary ammonium salts.
Methonium compounds. See also the same journal, 1948, 162, 810.
GMN 1929.3 · https://historyofmedicine.com/id/6466
1948 DALLDORF, Gilbert Julius (1900 – 1979); SICKLES, Grace Mary (1898 – 1959)
An unidentified, filterable agent isolated from the feces of children with paralysis.
Isolation of the Coxsackie virus from the stool of a patient residing in Coxsackie, New York.
GMN 5545 · https://historyofmedicine.com/id/6761
1949 EVANS, Herbert McLean (1882 – 1971); LI, Choh Hao (1913 – 1987); SIMPSON, Miriam Elizabeth (1894 – 1991)
Isolation of pituitary follicle-stimulating hormone (FSH).
By Choh Hao Li and colleagues.
GMN 1175.2 · https://historyofmedicine.com/id/1588
1949 PATON, Sir William Drummond Macdonald (1917 – 1993); ZAIMIS, Eleanor (1915 – 1982)
The pharmacological actions of polymethylene bistrimethyl-ammonium salts.
Introduction of hexamethonium bromide.
GMN 5727 · https://historyofmedicine.com/id/6468
1949 BOVET, Daniel (1907 – 1992); BOVET-NITTI, Filomena (1909 – 1994); ET AL
Proprietà farmacodinamiche di alcuni derivati della succinilcolina dotati di azione curarica. Esteri di trialchiletanolammonio di acidi bicarbossilici alifatici.
Introduction of succinylcholine chloride. With S. Guarino, V. G. Longo, and M. Marotta.
GMN 5728 · https://historyofmedicine.com/id/6471
1949 CUTTINO, John Tindal (1912 – 1988); MCCABE, Anne M.
Pure granulomatous nocardiosis: a new fungus disease distinguished by intracellular parasitism. A description of a new disease in man due to a hitherto undescribed organism, Nocardia intracellularis, n.sp., including a study of the biological and pathogenic properties of this species.
Nocardiosis described.
GMN 5515 · https://historyofmedicine.com/id/6522
1949 WALKER, Helen Edith
The Negro in the medical profession.
Publications of the University of Virginia, Phelps-Stokes fellowship papers, no. 18.
GMN 8084 · https://historyofmedicine.com/id/10260
1950 SMITH, Audrey Ursula (1915 – 1981)
Prevention of haemolysis during freezing and thawing red blood-cells.
Demonstration that human blood diluted with equal volumes of 30% glycerol in Ringer’s lactate solution could be frozen at -79° C and thawed after eight weeks without damage.
GMN 2028.1 · https://historyofmedicine.com/id/2061
1950 BRAZIER, Mary Agnes Burniston Brown (1904 – 1995)
Bibliography of electroencephalography, 1875-1948. Electroencephalography and Clinical Neurophysiology, Suppl. No. 1
Covers both normal and disease states. Suppl. No. 23 (1964), ed. M. Fink, covers the period 1951-62.
GMN 5016 · https://historyofmedicine.com/id/6603
1950 MCCLINTOCK, Barbara (1902 – 1992)
The origin and behavior of mutable loci in maize.
"In the summer of 1944 at Cold Spring Harbor Laboratory, McClintock systematic studies on the mechanisms of the mosaic color patterns of maize seed and the unstable inheritance of this mosaicism.[44] She identified tw…
GMN 12063 · https://historyofmedicine.com/id/14272
1951 HAZEN, Elizabeth Lee (1885 – 1975); BROWN, Rachel Fuller (1898 – 1980)
Fungicidin, an antibiotic produced by a soil actinomycete.
Isolation of nystatin (fungicidin).
GMN 1945.4 · https://historyofmedicine.com/id/2811
1951 ANDERSON, Fannie
Doctors under three flags.
Covers the history of medicine in Detroit and Michigan between 1701 and 1837 when Michigan became a state. Digital facsimile from the Hathi Trust at this link.
GMN 10293 · https://historyofmedicine.com/id/12484
1951 MORRISSEY, Alice B.; RUSK, Howard A. (1901 – 1989)
Rehabilitation nursing. Foreward by Howard A. Rusk.
The first book on rehabilitation nursing, including a historical survey of rehabilitation and a study of the incidence of disability in the U.S. Morrissey conducted her research in association with the Institute of Ph…
GMN 14367 · https://historyofmedicine.com/id/16699
1952 MOLDENKE, Harold Norman (1909 – 1996); MOLDENKE, Alma Lance Ericson (1908 – 1997)
Plants of the Bible.
The most comprehensive treatise available on plants and plant products mentioned in the Bible.
GMN 2068 · https://historyofmedicine.com/id/2362
1952 BIGGS, Rosemary Peyton (1921 – 2001); ET AL
Christmas disease, a condition previously mistaken for haemophilia.
Christmas disease, hemophilia B, due to lack of Factor IX. Named after the patient whose case was the first recorded example. With six co-authors.
GMN 3108.1 · https://historyofmedicine.com/id/3824
1952 ELION, Gertrude Belle (1918 – 1999); HITCHINGS, George Herbert (1905 – 1998); BURGI, E.; ET AL
Studies on condensed pyrimidine system. IX. The synthesis of some 6-substituted purines.
Synthesis of 6-mercaptopurine. In 1988 Gertrude Elion shared the Nobel Prize in Physiology or Medicine with George Hitchings and Sir James Black “for their discoveries of important principles for drug treatment.”
GMN 3108.2 · https://historyofmedicine.com/id/3825
