1943 GIBSON, Thomas (1915 – 1993); MEDAWAR, Sir Peter Brian (1915 – 1987)
The fate of skin homografts in man.
Gibson and Medawar placed the laws of transplantation on a firm scientific basis. A later paper by Medawar (J. Anat. [Lond.], 1944, 78, 176- 99) demonstrated that the mechanism of rejection of transplanted tissues is …
GMN 2578.4 · https://historyofmedicine.com/id/4141
1943 SANO, Machteld Elisabeth (1903 – 1993)
Skin grafting. A new method based on the principles of tissue culture.
First use of fibrin glue for skin grafting. See also Surg. Gynec. Obstet., 1943, 77, 510-13.
GMN 5765 · https://historyofmedicine.com/id/6725
1950 LAWLER, Richard H. (1895 – 1982); ET AL
Homotransplantation of the kidney in human; preliminary report.
Report of first human patient to survive a kidney transplant. The operation was on June 17, 1950, and the patient was discharged on August 26. With four co-authors. See No. 4257.
GMN 4256.1 · https://historyofmedicine.com/id/5174
1951 MEDAWAR, Sir Peter Brian (1915 – 1987); BILLINGHAM, Rupert Everett (1921 – 2002)
The technique of free skin grafting in mammals.
This "paper facilitated the later discovery of `actively acquired tolerance' and the definition of the principal laws of transplantation tolerance. Thus, it was in a series of classic experiments (stemming from this J…
GMN 13595 · https://historyofmedicine.com/id/15874
1954 MEDAWAR, Sir Peter Brian (1915 – 1987); BILLINGHAM, Rupert Everett (1921 – 2002); BRENT, Leslie Baruch (1925 – 2019); SPARROW, Elizabeth M.
Quantitative studies on tissue transplantation immunity. I. The survival times of skin homografts exchanged between members of different inbred strains of mice. II. The origin, strength and duration of actively and adoptively acquired immunity.
Experimental production of immunological tolerance by Billingham and colleagues.Paper II distinguished adoptive from passive immunization. E. M. Sparrow was a co-author of paper I.
GMN 2578.12 · https://historyofmedicine.com/id/4149
1954 MITCHISON, Nicholas Avrion (1928 – )
Passive transfer of transplantation immunity.
Preliminary notice in Nature (Lond.), 1953, 171, 267-68.
GMN 2578.15 · https://historyofmedicine.com/id/4152
1955 WELCH, Charles Stuart (1909 – )
A note on transplantation of the whole liver in dogs.
Placement of auxiliary whole liver.
GMN 3666.1 · https://historyofmedicine.com/id/4819
1955 HUME, David Milford (1917 – 1973); MERRILL, John Putnam (1917 – 1986); THORN, George Widmer (1906 – 2004); ET AL
Experiences with renal homotransplantation in the human. Report of nine cases.
With Benjamin F. Miller. Digital facsimile from PubMedCentral at this link.
GMN 4256.3 · https://historyofmedicine.com/id/5194
1956 MURRAY, Donald Walter Gordon (1894 – 1976)
Homologous aortic-valve-segment transplants as surgical treatment for aortic and mitral insufficiency.
First successful aortic valve homograft. For report of six-year follow-up, see A. J. Kerwin, et al., New Engl. J. Med.,1962, 266,852.
GMN 3047.8 · https://historyofmedicine.com/id/3579
1956 MERRILL, John Putnam (1917 – 1986); MURRAY, Joseph Edward (1919 – 2012); HARRISON, John Hartwell (1909 – 1983); ET AL
Successful homotransplantation of the human kidney between identical twins.
This was the first successful kidney transplant. The patient, both of whose own kidneys had been removed, was alive 11 months after the transplant. With Warren R. Guild. See No. 4256.1. In 1990 Joseph Murray shared th…
GMN 4257 · https://historyofmedicine.com/id/5197
1957 THOMAS, Edward Donnall (1920 – 2012); LOCHTE, Harry L. Jr.; LU, Wan Ching; ET AL
Intravenous infusion of bone marrow in patients receiving radiation and chemotherapy.
Thomas and colleagues reported the first bone marrow transplants. They described the treatment of six patients with cancers and/leukemia and one patient with multiple myeloma. Three of the patients died, two responded…
GMN 13594 · https://historyofmedicine.com/id/15873
1958 SNELL, George Davis (1903 – 1996)
Histocompatibility genes of the mouse.
Snell made fundamental contributions to transplantation genetics. At his suggestion genes governing transplantation were called histocompatibility genes and Gorer’s Antigen II became Histocompatibility-2 (H-2). In 198…
GMN 2578.30 · https://historyofmedicine.com/id/4268
1959 MOORE, Francis Daniels (1913 – 2001)
One-stage homotransplantation of the liver following total hepatectomy in dogs.
With nine co-authors.
GMN 3666.2 · https://historyofmedicine.com/id/4820
1959 MATHÉ, Georges (1922 – 2010); JAMMET, H.; PENDIC, B.; ET AL
Transfusions et greffes de moelle osseuse homologue chez des humains irradiés a haute dos accidentellement.
Order of authorship in the original publication: Mathé, Jammet, Pendic et al. Mathé performed the first bone marrow graft between unrelated donors and hosts in order to save six Yugoslavian nuclear researchers who had…
GMN 13334 · https://historyofmedicine.com/id/15602
1959 BILLINGHAM, Rupert Everett (1921 – 2002); BRENT, Leslie Baruch (1925 – 2019)
Quantitative studies of tissue transplantation immunity. IV. Induction of tolerance in newborn mice and studies on the phenomenon of Runt Disease.
First description of what became known as Graft-versus-host disease (GvDH). This the authors initially called "graft against host (GAH)." The authors cited three conditions, later known as the Billingham criteria, whi…
GMN 13526 · https://historyofmedicine.com/id/15803
1960 LOWER, Richard Rowland (1929 – 2008); SHUMWAY, Norman Edward (1923 – 2006)
Studies on orthotopic homotransplantation of the canine heart.
Important experimental technique (Shumway); reported eight heart homotransplants.
GMN 3047.14 · https://historyofmedicine.com/id/3613
1960 WOODRUFF, Sir Michael Francis Addison (1911 – 2001)
The transplantation of tissues and organs.
Contains an unusually extensive bibliography.
GMN 13195 · https://historyofmedicine.com/id/15456
1962 DEMIKHOV, Vladimir Petrovich (Влади́мир Петро́вич Де́михов) (1916 – 1998); HAIGH, Basil (1919 – 2005)
Peresadka zhiznenno vazhnykh organov v eksperimente. Experimental transplantation of vital organs. Authorized translation from the Russian by Basil Haigh.
Demikhov coined the term transplantology, and this work, first published in Russian in 1960, and translated and published in 1962 in New York, Berlin and Madrid, was the first monograph on transplantation of organs an…
GMN 7946 · https://historyofmedicine.com/id/10121
1963 STARZL, Thomas Earl (1926 – 2017)
Homotransplantation of the liver in humans.
First human liver transplant (three patients; one died during operation, the second after 7.5 days, and the third after 22 days). With five co-authors.
GMN 3666.3 · https://historyofmedicine.com/id/4821
1964 HARDY, James Daniel (1918 – 2003); ET AL
Heart transplantation in man: Developmental studies and report of a case.
Heart transplant from a chimpanzee into a man; unsuccessful. Hardy was expecting the donor heart to be obtained from a relatively young patient dying of brain damage, but the patient went into terminal myocardial fail…
GMN 3047.19 · https://historyofmedicine.com/id/3632
1964 MOORE, Francis Daniels (1913 – 2001)
Give and take: The development of tissue transplantation.
GMN 8719 · https://historyofmedicine.com/id/10897
1967 BARNARD, Christiaan Neethling (1922 – 2001)
A human cardiac transplant: An interim report of a successful operation performed at Groote Schuur Hospital, Cape Town.
First human heart transplant. The operation was on Dec. 3, 1967, and the patient died on Dec. 21.
GMN 3047.20 · https://historyofmedicine.com/id/3636
1968 SNELL, George Davis (1903 – 1996)
The H-2 locus of the mouse: observations and speculations concerning its comparative genetics and its polymorphism.
Antigen II, discovered by Gorer (No. 2576.5), was studied by Snell and became known as the product of the H-2 locus, the fundamental locus in the history of mammalian transplant biology.
GMN 2578.38 · https://historyofmedicine.com/id/4299
1973 LACY, Paul Easton (1924 – 2005); KEMP, Charles B.; KNIGHT, Michael J.; SHARP, David W.
Transplantation of isolated pancreatic islets into the portal vein of diabetic rats.
Lacy and colleagues showed that transplanation of murine pancreatic islet tissue into the portal vein of diabetic rats of the same inbred strain normalized the sugar levels and urine output of the rats that received t…
GMN 14161 · https://historyofmedicine.com/id/16476
1974 SWAZEY, Judith P. (1939 – ); FOX, Renée Claire (1928 – )
The courage to fail: A social view of organ transplants and dialysis.
Includes chapters on the heart transplantation moratorium and the artificial heart.
GMN 12343 · https://historyofmedicine.com/id/14567
1975 TAYLOR, Geofrrey Ian; ET AL
The free vascularized bone graft. A clinical extension of microvascular techniques.
First clinically successful free bone graft with microvascular anastomosis in which a fibular segment was transferred to the contralateral leg to reconstruct a large tibial defect. With G.D.H. Miller and F. J.Ham.
GMN 5766.4 · https://historyofmedicine.com/id/6741
1976 BOREL, J. F.; ET AL
Biological effects of cyclosporin A: a new antilymphocytic agent.
The immunosuppressive cyclosporin A, instrumental in the success of organ transplants. With C. Feurer, H.U. Gubler & H. Strähelin.
GMN 1931.71 · https://historyofmedicine.com/id/2763
1981 KLASEN, Henk J.
History of free skin grafting.
Comprehensive work, with hundreds of bibliographical references. No index.
GMN 5768.4 · https://historyofmedicine.com/id/6772
1982 SHUMWAY, Norman Edward (1923 – 2006); REITZ, Bruce A.
Heart-lung transplantation: Successful therapy for patients with pulmonary vascular disease.
First successful heart-lung transplant, performed on March 9, 1981, after nearly four years of testing on primates. Abstract "We report our initial experience with three patients who received heart-lung transplants. T…
GMN 10659 · https://historyofmedicine.com/id/12852
1991 TERASAKI, Paul Ichiro (1929 – 2016)
History of transplantation: Thirty-five recollections.
GMN 8774 · https://historyofmedicine.com/id/10952
1996 BRENT, Leslie Baruch (1925 – 2019)
A history of transplantation immunology.
Written by one of the founders of the science.
GMN 12794 · https://historyofmedicine.com/id/15040
2003 TILNEY, Nicholas L. ( – 2013)
Transplant: From myth to reality.
GMN 10143 · https://historyofmedicine.com/id/12332
2003 TINEY, Nicolas L.
Transplant: From myth to reality.
"... organ transplantation has become a generally effective and routine treatment for patients with organ failure. In this book, a well-known expert in the fields of clinical transplantation and transplantation resear…
GMN 12241 · https://historyofmedicine.com/id/14455
2008 LEDERER, Susan E. (1955 – )
Flesh and blood: Organ transplantation and blood transfusion in twentieth-century America.
GMN 10362 · https://historyofmedicine.com/id/12554
2010 SCHLICH, Thomas (1962 – )
The origins of organ transplantation: Surgery and laboratory science 1880-1930.
GMN 8756 · https://historyofmedicine.com/id/10934
2012 HAMILTON, David Ninian Hay
A history of organ transplantation: Ancient legends to modern practice.
GMN 8777 · https://historyofmedicine.com/id/10955
2012 MILLER, Franklin G. (1948 – ); TRUOG, Robert D.
Death, dying, and organ transplantation: Reconstructing medical ethics at the end of life.
GMN 10345 · https://historyofmedicine.com/id/12537
