1586 DONATI, Marcello (1538 – 1602)
De medica historia mirabili.
An early history of diseases, with extensive sections on ophthalmology (ff. 66-77) and urology (ff. 260-271). Lib. IV, Cap. iii, page 196 contains the first recorded case of gastric ulcer. Lib. VI. cap. iii contains t…
GMN 3417 · https://historyofmedicine.com/id/5319
1727 RAWLINSON, Christopher
A preternatural perforation found in the upper part of the stomach, with the symptoms it produced.
First reported case of perforating gastric ulcer.
GMN 3420 · https://historyofmedicine.com/id/5341
1746 HAMBERGER, Georg Erhard (1697 – 1755)
De ruptura intestini duodeni.
First description of duodenal ulcer.
GMN 3424 · https://historyofmedicine.com/id/5349
1793 BAILLIE, Matthew (1761 – 1823)
The morbid anatomy of some of the most important parts of the human body.
Baillie was a nephew and pupil of William Hunter. The above is the first systematic textbook of morbid anatomy, treating the subject for the first time as an independent science. See also Nos. 2736, 3167.1. Baillie wa…
GMN 2281 · https://historyofmedicine.com/id/2898
1793 PENADA, Jacopo (1748 – 1828)
Saggio d’osservazioni, e memoire sopra alcuni case singolari riscontrati nell’esercizio della medicina, e della anatomia pratica.
Includes (pp. 33-56) an account of perforating duodenal ulcer.
GMN 3428 · https://historyofmedicine.com/id/5373
1842 CURLING, Thomas Blizard (1811 – 1888)
On acute ulceration of the duodenum, in cases of burn.
“Curling’s ulcer”. Although not first to report duodenal ulcers as a complication of burns, Curling correlated the work of previous writers on the subject and directed attention to it.
GMN 3445 · https://historyofmedicine.com/id/5486
1855 BERGERON, Étienne Jules (1817 – 1900)
Note sur l’emploi du chlorate de potasse dans le traitement de la stomatite ulcéreuse.
Classic description of ulcero-membranous stomatitis and its treatment.
GMN 3453 · https://historyofmedicine.com/id/5577
1857 BRINTON, William (1823 – 1867)
On the pathology, symptoms, and treatment of ulcer of the stomach.
A comprehensive account of peptic (duodenal) ulcer; includes a review of the results of more than 7,000 post mortems.
GMN 3454 · https://historyofmedicine.com/id/5579
1864 KRAUSS, Julius (1841 – )
Das perforirende Geschwür im Duodenum.
The first comprehensive study of duodenal ulcer. Commercial edition, Berlin: A. Hirschwald, 1865. Digital facsimile of the 1864 edition from the Bayerische Staatsbibliothek at this link. Digital facsimile of the 1865 …
GMN 3461 · https://historyofmedicine.com/id/5600
1892 KRIEGE, Hermann; HEUSNER, Ludwig (1843 – 1916)
Ein Fall von einem frei in die Bauchhöhle perforirten Magengeschwür; Laparotomie; Naht der Perforationsstelle; Heilung.
In 1892 Ludwig Heusner (1846-1916) successfully sutured a perforated gastric ulcer, the first successful case on record. It was reported by H. Kriege.
GMN 3505 · https://historyofmedicine.com/id/3946
1893 PERRY, Sir Edwin Cooper (1856 – 1938); SHAW, Lauriston Elgie (1859 – 1923)
On diseases of the duodenum.
A careful examination of the records of post mortems carried out at Guy’s Hospital, 1826-92, was made by Perry and Shaw, who showed that of 70 reports of duodenal ulcer, ten occurred in cases of severe burns.
GMN 3510 · https://historyofmedicine.com/id/3975
1910 HAUDEK, Martin (1880 – 1931)
Zur röntgenologischen Diagnose der Ulzerationen in der Pars media des Magens.
First demonstration of the characteristic niche in gastric ulcer.
GMN 3533 · https://historyofmedicine.com/id/4029
1910 MOYNIHAN, Berkeley George Andrew (1865 – 1936)
Duodenal ulcer.
Moynihan greatly advanced our knowledge of duodenal ulcer. He developed the concept of the so-called ulcer sequence, pain-food-ease, and he stressed the well-ordered sequence of symptoms. More than any other he establ…
GMN 3535 · https://historyofmedicine.com/id/4033
1915 SIPPY, Bertram Welton (1866 – 1924)
Gastric and duodenal ulcer; medical cure by an efficient removal of gastric juice corrosion.
“Sippy diet” for the treatment of peptic ulcer.
GMN 3541 · https://historyofmedicine.com/id/4047
1928 KONJETZNY, Georg Ernst (1880 – 1957)
Die Entzündungen des Magens. In: F. Henke & O. Lubarsch: Handbuch der speziellen pathologischen Anatomie und Histologie, 4, Heft 2, 768-1116.
Konjetzny suggested that peptic ulceration is the sequel to a specific form of gastritis.
GMN 3546 · https://historyofmedicine.com/id/4057
1929 HURST, Sir Arthur Frederick (1879 – 1944); STEWART, Matthew John (1885 – 1956)
Gastric and duodenal ulcer.
GMN 3547 · https://historyofmedicine.com/id/4058
1932 CUSHING, Harvey Williams (1869 – 1939)
Papers relating to the pituitary body, hypothalamus, and para-sympathetic nervous system.
Cushing advanced the theory that the hypothalamus is responsible for the development of peptic ulcer (see p. 175 et seq.). This work contains his four principal contributions to pituitary-hypothalamic interrelationshi…
GMN 3552 · https://historyofmedicine.com/id/4063
1943 DRAGSTEDT, Lester Reynold (1893 – 1975); OWENS, Frederick Mitchum (1913 – 2004)
Supra-diaphragmatic section of the vagus nerves in treatment of duodenal ulcer.
Vagotomy for peptic ulcer.
GMN 3557 · https://historyofmedicine.com/id/4068
1955 ZOLLINGER, Robert Milton (1903 – 1992); ELLISON, Edwin Homer (1918 – 1970)
Primary peptic ulcerations of the jejunum associated with islet cell tumors of the pancreas.
Zollinger-Ellison syndrome.
GMN 3558.2 · https://historyofmedicine.com/id/4071
1983 MARSHALL, Barry James (1951 – ); WARREN, John Robin (1937 – )
Unidentified curved bacilli on gastric epithelium in active chronic gastritis.
In 2005 Marshall and Warren shared the Nobel prize in Physiology or Medicine "for their discovery of the bacterium Helicobacter pylori and its role in gastritis and peptic ulcer disease." See also their follow-up pape…
GMN 8475 · https://historyofmedicine.com/id/10652
