1936 REICHSTEIN, Tadeusz (1897 – 1996)
Über Bestandteile der Nebennieren-Rinde. VI. Trennungsmethoden sowie Isolierung der Substanzen Fa, H, und j.
Isolation of Compound Fa, identical with Compounds E and F. "In the mid-1930s Edward Kendall and Tadeus Reichstein succeeded in isolating and analyzing the composition of a number of similar hormones derived from the …
GMN 1153 · https://historyofmedicine.com/id/1463
1936 –1939 VAN DYKE, Harry Benjamin (1895 – 1971)
The physiology and pharmacology of the pituitary body. 2 vols.
Includes an extensive bibliography.
GMN 1172 · https://historyofmedicine.com/id/1574
1936 MACCORQUODALE, Donald William (1898 – 1986); ET AL
The isolation of the principal estrogenic substance of liquor folliculi.
Isolation of oestradiol. With S. A. Thayer and E. A. Doisy.
GMN 1202 · https://historyofmedicine.com/id/1826
1937 FREMERY, P. de; ET AL
Corticosteron, a crystallized compound with the biological activity of the adrenal-cortical hormone.
Isolation of corticosterone. With E. Laqueur, T. Reichstein, R. W. Spanhoff, and I. E. Uyldert.
GMN 1154 · https://historyofmedicine.com/id/1468
1937 YOUNG, Sir Frank George (1908 – 1988)
Permanent experimental diabetes produced by pituitary (anterior lobe) injections.
Anterior pituitary diabetogenic hormone.
GMN 1173 · https://historyofmedicine.com/id/1576
1940 EVANS, Herbert McLean (1882 – 1971); LI, Choh Hao (1913 – 1987); SIMPSON, Miriam Elizabeth (1894 – 1991)
Interstitial cell stimulating hormone. II. Method of preparation and some physico-chemical studies.
Choh Hao Li and colleagues isolated of the interstitial cell stimulating (luteinizing) hormone.
GMN 1173.1 · https://historyofmedicine.com/id/1578
1943 EVANS, Herbert McLean (1882 – 1971); LI, Choh Hao (1913 – 1987); SIMPSON, Miriam Elizabeth (1894 – 1991)
Adrenocorticotropic hormone.
Choh Hao Li and colleagues Isolated pure adrenocorticotropic hormone (ACTH) from sheep pituitary glands.
GMN 1174 · https://historyofmedicine.com/id/1580
1943 SAYERS, George (1914 – ); LONG, Cyril Norman Hugh (1901 – 1970); WHITE, Abraham
Preparation and properties of pituitary adrenocorticotropic hormone.
Isolation of ACTH from swine pituitaries.
GMN 1175 · https://historyofmedicine.com/id/1583
1945 EVANS, Herbert McLean (1882 – 1971); LI, Choh Hao (1913 – 1987); SIMPSON, Miriam Elizabeth (1894 – 1991)
Isolation and properties of the anterior hypophyseal growth hormone.
Choh Hao Li and colleagues isolated the anterior pituitary growth hormone.
GMN 1175.1 · https://historyofmedicine.com/id/1585
1949 BERGSTRÖM, Sune (1916 – 2004); ET AL
Isolation of nor-adrenaline from the adrenal gland.
With U.S. von Euler and U. Hamberg. See also fuller account in Acta physiol. scand., 1950, 20, 101-8. Noradrenaline was independently isolated by B. F. Tullar, Science, 1950, 109, 536-7.
GMN 1155 · https://historyofmedicine.com/id/1472
1949 EVANS, Herbert McLean (1882 – 1971); LI, Choh Hao (1913 – 1987); SIMPSON, Miriam Elizabeth (1894 – 1991)
Isolation of pituitary follicle-stimulating hormone (FSH).
By Choh Hao Li and colleagues.
GMN 1175.2 · https://historyofmedicine.com/id/1588
1952 GRUNDY, Hilary M.; ET AL
Isolation of a highly active mineralocorticoid from beef adrenal extract.
Isolation of aldosterone. With S. A. Simpson and J. F. Tait.
GMN 1155.1 · https://historyofmedicine.com/id/1476
1952 WOODWARD, Robert Burns (1917 – 1979); SONDHEIMER, Franz (1926 – 1981); ET AL
The total synthesis of steroids.
Synthesis of cortisone by Woodward and colleagues. With F. D. Taub, K. Heusler, and W. M. McLamore.
GMN 1155.2 · https://historyofmedicine.com/id/1484
1953 GROSS, Jack (1921 – 1994); PITT-RIVERS, Rosalind Venetia Lane Fox (1907 – 1990)
3:5:3'-Triiodothyronine. I. Isolation from thyroid gland and synthesis.
Discovery of the second thyroid hormone, triiodothyronine. Digital facsimile from PubMedCentral at this link.
GMN 1138.1 · https://historyofmedicine.com/id/1350
1953 VIGNEAUD, Vincent du (1901 – 1978)
The synthesis of an octapeptide amide with the hormonal activity of oxytocin.
Synthesis of oxytocin. With C. Ressler, J. M. Swan, C. W. Roberts, P. G. Katsoyannis, and S. Gordon. In 1955 Vigneaud was awarded the Nobel Prize in Chemistry "for his work on biochemically important sulphur compounds…
GMN 1175.3 · https://historyofmedicine.com/id/1591
1954 VIGNEAUD, Vincent du (1901 – 1978)
A synthetic preparation possessing biological properties associated with arginine-vasopressin.
Synthesis of vasopressin. With D. T. Gish and P. G. Katsoyannis.
GMN 1175.4 · https://historyofmedicine.com/id/1594
1955 SANGER, Frederick (1918 – 2013)
The disulphide bonds of insulin.
Sanger sequenced the amino acids of insulin, the first of any protein. His work “revealed that a protein has a definite constant, genetically determined sequence—and yet a sequence with no general rule for its assembl…
GMN 1207 · https://historyofmedicine.com/id/1852
1960 HOWARD, John Malone (1919 – 2011); JORDAN, George Lyman (1921 – )
Surgical diseases of the pancreas.
The first comprehensive textbook on pancreatic disease.
GMN 7878 · https://historyofmedicine.com/id/10050
1962 COPP, Douglas Harold (1915 – 1998); ET AL
Evidence for calcitonin – a new hormone from the parathyroid that lowers blood calcium.
With E. C. Cameron, B. A. Cheney, A. G. F. Davidson, and K. G. Henze.
GMN 1138.2 · https://historyofmedicine.com/id/1351
1962 BERGSTRÖM, Sune (1916 – 2004); SAMUELSSON, Bengt Ingemar (1934 – ); ET AL
The structure of prostaglandin E, F1 and F2.
In this and subsequent papers Bergström and Samuelsson elucidated the chemical structure of prostaglandins. In 1982 the Nobel Prize in Physiology or Medicine was awarded jointly to Sune K. Bergström, Bengt I. Samuelss…
GMN 1931.4 · https://historyofmedicine.com/id/2757
1965 KUNG, Yueh-Ting; ET AL
Total synthesis of crystalline bovine insulin.
GMN 1207.1 · https://historyofmedicine.com/id/1854
1973 LACY, Paul Easton (1924 – 2005); KEMP, Charles B.; KNIGHT, Michael J.; SHARP, David W.
Transplantation of isolated pancreatic islets into the portal vein of diabetic rats.
Lacy and colleagues showed that transplanation of murine pancreatic islet tissue into the portal vein of diabetic rats of the same inbred strain normalized the sugar levels and urine output of the rats that received t…
GMN 14161 · https://historyofmedicine.com/id/16476
2002 HOWARD, John Malone (1919 – 2011); HESS, Walter (1918 – )
History of the pancreas: Mysteries of a hidden organ.
GMN 7877 · https://historyofmedicine.com/id/10049
