1898 CURIE, Pierre (1859 – 1906); CURIE, Marie Sklodowska (1867 – 1934)
Sur une substance nouvelle radio-active, contenue dans la pechblende.
The Curies, studying the radioactivity of minerals containing uranium and thorium, isolated from pitchblend a substance which they called radium and which they showed to possess an astonishing degree of radioactivity.…
GMN 2003 · https://historyofmedicine.com/id/1914
1923 HEVESY, George Charles de (1885 – 1966)
The absorption and translocation of lead by plants: A contribution to the application of the method of radioactive indicators in the investigation of the change of substance in plants.
The first application of radioactive tracers in biological studies. Digital facsimile from PubMedCentral at this link. Hevesy received the 1943 Nobel Prize in Chemistry "for his work on the use of isotopes as tracers …
GMN 9333 · https://historyofmedicine.com/id/11515
1924 HEVESY, George Charles de (1885 – 1966); LOMHOLT, Sven; CHRISTIANSEN, J. A.
Radiochemical method of studying the circulation of lead in the body.
First application of radioactive tracers in animals, specifically rabbits and guinea pigs. See also Hevesy et al, "Radiochemical method of studying the circulation of bismuth in the body," C. R. Acad. Sci. (Paris) 178…
GMN 9334 · https://historyofmedicine.com/id/11516
1926 –1927 BLUMGART, Hermann Ludwig (1895 – 1977); WEISS, Soma (1898 – 1942)
Studies in the velocity of blood flow.
First practical method of measuring circulation time. "In 1925, Hermann Blumgart performed the first diagnostic procedure using radioactive indicators on humans; this first is well recognized. Less well recognized is …
GMN 796 · https://historyofmedicine.com/id/130
1927 BLUMGART, Hermann Ludwig (1895 – 1977); YENS, Otto C.
Studies on the velocity of blood flow: I. The method utilized.
Reports the first diagnostic procedure, done in 1925, using radioactive indicators on humans. "Less well recognized is the fact that Blumgart and his coworker Otto C. Yens, then a medical student, developed the first …
GMN 9335 · https://historyofmedicine.com/id/11517
1934 JOLIOT-CURIE, Jean Frédéric (1900 – 1958); JOLIOT-CURIE, Irène (1897 – 1956)
I. Un nouveau type de radioactivité. II. Séparation chimique des nouveaux radioéléments émetteur d’électrons positifs.
Discovery of artificially produced radionuclides or radioisotopes. In February 1934, the Joliot-Curies reported the first artificial production of radioactive material after discovering radioactivity in aluminum foil …
GMN 9340 · https://historyofmedicine.com/id/11522
1938 SEGRÈ, Emilio Gino (1905 – 1989); SEABORG, Glenn Theodore (1912 – 1999)
Nuclear isomerism in element 43.
Isolation of the metastable isotope technetium-99m, the most commonly used medical radioistope, used in tens of millions of medical diagnostic procedures annually. Segrè discovered the first artifical element Techneti…
GMN 9339 · https://historyofmedicine.com/id/11521
1939 LAWRENCE, John Hundale (1904 – 1991); ET AL
Studies on leukemia with the aid of radioactive phosphorus.
Therapeutic use of radioactive isotopes for the treatment of leukemia. John H. Lawrence was the brother of Ernest Orlando Lawrence, inventor of the cyclotron; John Lawrence also worked at the Lawrence Berkeley Nationa…
GMN 3098 · https://historyofmedicine.com/id/3792
1940 KERST, Donald William (1911 – 1993)
Acceleration of electrons by magnetic induction.
Betatron. Continued as Kerst, "The acceleration of elecrons by magnetic induction," Phys. Rev., 60 (1941) 47-52. Digital facsimile of the 1941 paper at this link.
GMN 2010.2 · https://historyofmedicine.com/id/3348
1940 LAWRENCE, John Hundale (1904 – 1991)
Nuclear physics and therapy: preliminary report on a new method for the treatment of leukemia and polycythemia.
Radio-phosphorus in treatment of leukemia.
GMN 3099 · https://historyofmedicine.com/id/3795
1946 ALVAREZ, Luis Walter (1911 – 1988)
The design of a proton linear accelerator.
Linear ion accelerator. In 1968 Alvarez received the Nobel Prize in Physics "for his decisive contributions to elementary particle physics, in particular the discovery of a large number of resonance states, made possi…
GMN 2659.5 · https://historyofmedicine.com/id/3361
1946 SEIDLIN, Samuel M. (1895 – 1955); MARINELLI, Leonidas D. (1906 – 1974); OSHRY, Eleanor
Radioactive iodine therapy: Effect on functioning metastases of adenocarcinoma of the thyroid.
Seidlin and Marinelli described the first successful treatment of a patient with thyroid cancer metastases using radioiodine (I-131). This paper demonstrated the potential of nuclear medicine as a medical specialty.
GMN 9338 · https://historyofmedicine.com/id/11520
1950 CASSEN, Benedict (1902 – 1972); ET AL
A sensitive directional gamma-ray detector.
Directional scintillation detector probe. Cassen assembled the first automated scanning system, comprised of a motor driven scintillation detector coupled to a relay printer. The scanner was initially used to image th…
GMN 2660.2 · https://historyofmedicine.com/id/3372
1989 WALLIS, Jerold Warren; KLEERUP, Eric C.
Three-dimensional display in nuclear medicine.
Maximum intensity projection (MIP) or MIP imaging, invented by Jerold Wallis, "is a method for 3D data that projects in the visualization plane the voxels with maximum intensity that fall in the way of parallel rays t…
GMN 12292 · https://historyofmedicine.com/id/14513
1990 BRUCER, Marshall (1913 – 1994)
A chronology of nuclear medicine.
GMN 9776 · https://historyofmedicine.com/id/11964
2003 PATTON, Dennis D.
The Birth of Nuclear Medicine Instrumentation: Blumgart and Yens, 1925.
Available online at http://jnm.snmjournals.org/content/44/8/1362.long.
GMN 9855 · https://historyofmedicine.com/id/12043
2006 WAGNER, Henry N. Jr. (1927 – 2012)
A personal history of nuclear medicine.
GMN 10975 · https://historyofmedicine.com/id/13171
2013 CREAGER, Angela N. H. (1963 – )
Life atomic: A history of radioisotopes in science and medicine.
GMN 9336 · https://historyofmedicine.com/id/11518
2014 MOULD, Richard F. (1939 – )
Annotated x-ray bibliography 1896-1945, also containing some selected references on nuclear physics, radioactivity & nuclear medicine.
GMN 11115 · https://historyofmedicine.com/id/13311
