An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to Circa 2020 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

15426 entries, 13280 authors and 1897 subjects. Updated: October 20, 2021

Browse by Entry Number 5200–5299

139 entries
  • 2378
  • 5200

A treatise on gonorrhoea virulenta, and lues venerea. 2 vols.

Edinburgh: J. Watson & G. Mudie, 1793.

Bell was the first to differentiate between gonorrhoea and syphilis.



Subjects: INFECTIOUS DISEASE › SEXUALLY TRANSMITTED DISEASES › Gonorrhoea & Trichomonas Infection, INFECTIOUS DISEASE › SEXUALLY TRANSMITTED DISEASES › Syphilis
  • 2380
  • 5201

Practical observations on the venereal disease, and on the use of mercury.

London: Sherwood, Gilbert & Piper, 1837.

“Colles’s law” is stated on. p. 304. Colles introduced small doses of mercury in the treatment of syphilis. He was Professor of Surgery at Dublin.



Subjects: INFECTIOUS DISEASE › SEXUALLY TRANSMITTED DISEASES, INFECTIOUS DISEASE › SEXUALLY TRANSMITTED DISEASES › Syphilis
  • 2381
  • 5202

Traité pratique des maladies vénériennes.

Paris: De Just Rouvier & E. Le Bouvier, 1838.

Includes the description of “Ricord’s chancre”, the initial lesion in syphilis. Ricord re-demonstrated the specific character of syphilis and divided it into the three stages, primary, secondary, and tertiary. 

Repeating Hunter’s experiment, Ricord proved that syphilis and gonorrhoea were separate diseases. After Hunter, he was the greatest authority on venereal disease. 

The first of several English translations appeared in 1842.



Subjects: INFECTIOUS DISEASE › SEXUALLY TRANSMITTED DISEASES, INFECTIOUS DISEASE › SEXUALLY TRANSMITTED DISEASES › Syphilis
  • 5203

Traité des affections de la peau symptomatiques de la syphilis.

Paris: J.-B. Baillière, 1852.

Bassereau defined chancroid clearly for the first time.



Subjects: DERMATOLOGY, INFECTIOUS DISEASE › SEXUALLY TRANSMITTED DISEASES › Syphilis
  • 5204

Coincidence du chancre syphilitique primitif avec la gale, la blénorrhagie, le chancre simple et la vaccine.

Gaz. méd. Lyon, 18, 160-63, Lyon, 1866.

Rollet recognized the possibility of mixed infection of one sore with syphilis and chancroid, thus establishing the dualist theory of venereal infection. The mixed chancre is named “Rollet’s disease”.



Subjects: INFECTIOUS DISEASE › SEXUALLY TRANSMITTED DISEASES, INFECTIOUS DISEASE › SEXUALLY TRANSMITTED DISEASES › Syphilis
  • 5204.1

Precis of operations performed in the wards of the first surgeon, Medical College Hospital, during the year 1881.

Indian med. Gaz., 17, 113-23, 1882.

MacLeod was first to draw attention to granuloma inguinale.



Subjects: COUNTRIES, CONTINENTS AND REGIONS › India, INFECTIOUS DISEASE › SEXUALLY TRANSMITTED DISEASES
  • 5205

Il virus dell’ ulcera venerea.

Gazz. int. Sci. med., 11, 44, 1889.

Announcement of the discovery of Haemophilus ducreyi (Ducrey’s bacillus), causal organism in chancroid.



Subjects: BACTERIOLOGY › BACTERIA (mostly pathogenic; sometimes indexed only to genus) › Gram-Negative Bacteria › Haemophilus, INFECTIOUS DISEASE › SEXUALLY TRANSMITTED DISEASES › Chancroid
  • 5205.1

The lupoid form of the so-called “groin ulceration” of this colony.

Brit. Guiana med. Annu., 8, 13-29, 1896.

Granuloma inguinale distinguished from other similar lesions in the genital region.



Subjects: COUNTRIES, CONTINENTS AND REGIONS › Guyana, INFECTIOUS DISEASE › SEXUALLY TRANSMITTED DISEASES
  • 4006
  • 5206

Handbuch der Haut-und Geschlechtskrankheiten. Hrsg…von J. JADASSOHN. 24 vols.

Berlin: Julius Springer, 19271937.


Subjects: DERMATOLOGY
  • 5207

Animalcules observés dans les matières purulentes et le produit des sécrétions des organes génitaux de l’homme et de la femme.

C. R. Acad. Sci. (Paris), 3, 385-86, Paris, 1836.

First description of Trichomonas vaginalis, which Donné at first believed to be the pernicious agent in gonorrhoea. He later admitted the organism to be a normal inhabitant of the female genital tract. Donné was, by this work, the first to describe living organisms in pathological conditions, as observed by modern methods. English translation in Kean (No. 2268.1).



Subjects: INFECTIOUS DISEASE › SEXUALLY TRANSMITTED DISEASES, MICROBIOLOGY
  • 5208

Ueber eine der Gonorrhoe eigentümliche Micrococcusform.

Zbl. med. Wiss., 17, 497-500, 1879.

Discovery of the gonococcus – causal organism in gonorrhoea.



Subjects: BACTERIOLOGY › BACTERIA (mostly pathogenic; sometimes indexed only to genus) › Gram-Negative Bacteria › Gonococcus, INFECTIOUS DISEASE › SEXUALLY TRANSMITTED DISEASES › Gonorrhoea & Trichomonas Infection
  • 5209

Ueber Bacterien bei den venerischen Krankheiten.

Charité-Ann., (1882), 7, 750-72, 1880.

Leistikow was first to report the cultivation of the gonococcus.



Subjects: BACTERIOLOGY › BACTERIA (mostly pathogenic; sometimes indexed only to genus) › Gram-Negative Bacteria › Gonococcus, INFECTIOUS DISEASE › SEXUALLY TRANSMITTED DISEASES › Gonorrhoea & Trichomonas Infection
  • 5209

Der Mikro-Organismus der gonorrhöischen Schleimhaut-Erkrankungen, Gonococcus-Neisser.

Dtsch. med. Wschr., 11, 508-09, 1885.

Bumm cultured the gonococcus. By human inoculations he demonstrated its pathogenicity in pure culture.



Subjects: BACTERIOLOGY › BACTERIA (mostly pathogenic; sometimes indexed only to genus) › Gram-Negative Bacteria › Gonococcus, INFECTIOUS DISEASE › SEXUALLY TRANSMITTED DISEASES › Gonorrhoea & Trichomonas Infection
  • 5210.1

Bericht über eine bei Kindern beobachtete Endemie infectiöser Colpitis.

Virchows Arch. path. Anat., 99, 251-76, 1885.

The gonococcus shown to be the cause of vulvovaginitis in children.



Subjects: INFECTIOUS DISEASE › SEXUALLY TRANSMITTED DISEASES › Gonorrhoea & Trichomonas Infection, PEDIATRICS
  • 5211

Die Blenorrhöe der Sexualorgane und ihre Complicationen.

Leipzig & Vienna: Franz Deuticke, 1888.


Subjects: INFECTIOUS DISEASE › SEXUALLY TRANSMITTED DISEASES, INFECTIOUS DISEASE › SEXUALLY TRANSMITTED DISEASES › Gonorrhoea & Trichomonas Infection
  • 5212

Ulcerative endocarditis due to the gonococcus; gonorrheal septicemia.

Johns Hopk. Hosp. Bull., 7, 57-63, 1896.

Thayer and Blumer found the gonococcus in cases of gonorrheal endocarditis.



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Endocarditis, INFECTIOUS DISEASE › Endocarditis, INFECTIOUS DISEASE › SEXUALLY TRANSMITTED DISEASES › Gonorrhoea & Trichomonas Infection
  • 5213

Ueber den Nachweis von Antikörpern im Serum eines an Arthritis gonorrhoica Erkrankten mittels Komplementablenkung.

Wien. klin. Wschr., 19, 894-95, 1906.

“Müller–Oppenheim reaction” – a complement fixation test for the diagnosis of gonorrhoea.



Subjects: INFECTIOUS DISEASE › SEXUALLY TRANSMITTED DISEASES › Gonorrhoea & Trichomonas Infection
  • 5213.1

La toxi-infection gonococcique expérimentale et son traitement chimiothérapique.

Presse méd., 45, 1371-73, 1937.

Levaditi and Vaisman showed that sulfanilamide protected mice against gonococcal infection.



Subjects: INFECTIOUS DISEASE › SEXUALLY TRANSMITTED DISEASES › Gonorrhoea & Trichomonas Infection, PHARMACOLOGY › PHARMACEUTICALS › Sulfonamides
  • 5214.1

The use of sulfanilamide in gonococcic infections. Preliminary report.

J. Amer. med. Assoc., 108, 1855-58, 1937.


Subjects: INFECTIOUS DISEASE › SEXUALLY TRANSMITTED DISEASES › Gonorrhoea & Trichomonas Infection, PHARMACOLOGY › PHARMACEUTICALS › Sulfonamides
  • 5214.1

Use of penicillin in sulfonamide resistant gonorrheal infections.

J. Amer. med. Assoc., 122, 289-92, 1943.

With E. N. Cook and L. Thompson.



Subjects: INFECTIOUS DISEASE › SEXUALLY TRANSMITTED DISEASES › Gonorrhoea & Trichomonas Infection, PHARMACOLOGY › Drug Resistance, PHARMACOLOGY › PHARMACEUTICALS › Antibiotics › Penicillin
  • 5215

A treatise on the venereal disease and its varieties.

London: Burgess & Hill, 1833.

On p. 371 commences the first description of lymphogranuloma venereum, which Wallace called “indolent primary syphilitic bubo”.



Subjects: INFECTIOUS DISEASE › SEXUALLY TRANSMITTED DISEASES, INFECTIOUS DISEASE › SEXUALLY TRANSMITTED DISEASES › Lymphogranuloma Venereum
  • 5216

Mémoire sur l’esthioméne, ou dartre rongeante de la région vulvo-anale.

Mém. Acad. nat. Méd (Paris), 14, 501-96, 1849.

Huguier gave the name esthiomène to the characteristic induration and discoloration of the affected parts in lymphogranuloma venereum.



Subjects: INFECTIOUS DISEASE › SEXUALLY TRANSMITTED DISEASES › Lymphogranuloma Venereum
  • 5217

Lymphogranulomatose inguinale subaiguë d’origine génitale probable, peut-être vénérienne.

Bull. Soc. méd. Hôp. Paris, 3 sér., 35, 274-88, 1913.

First important description. Sometimes called “Nicolas–Favre disease” and “Nicolas–Durand–Favre disease”.



Subjects: INFECTIOUS DISEASE › SEXUALLY TRANSMITTED DISEASES › Lymphogranuloma Venereum
  • 5218

Eine neue Hautreaktion bei “Lymphogranuloma inguinale”.

Klin. Wschr., 4, 2148-49, 1925.

The Frei skin test for the diagnosis of lymphogranuloma venereum.



Subjects: INFECTIOUS DISEASE › SEXUALLY TRANSMITTED DISEASES › Lymphogranuloma Venereum
  • 5219

Contribución al estudio de la linfogranulomatosis inguinal subaguda o ulcera venérea adenógena de Nicolás y Favre.

Act. dermo-sifiliogr. (Madr.), 20, 122-75, 1927.

Gay Prieto was the first actually to see the infective agent of lymphogranuloma venereum.



Subjects: COUNTRIES, CONTINENTS AND REGIONS › Spain, INFECTIOUS DISEASE › SEXUALLY TRANSMITTED DISEASES › Lymphogranuloma Venereum
  • 5220

Meningo-enzephalitische Veränderungen bei Affen nach intra-cerebraler Impfung mit Lymphogranuloma inquinale.

VIII Congr. int. Derm. Syph. Copenhague C. R. Séances, 1147-49, 1930, 1931.

The authors transmitted lymphogranuloma venereum to animals and attributed it to a virus. See also C. R. Soc. Biol. (Paris), 1931, 106, 802-03.



Subjects: INFECTIOUS DISEASE › SEXUALLY TRANSMITTED DISEASES › Lymphogranuloma Venereum
  • 5221

A sixth venereal disease. Climatic bubo, lymphogranuloma inguinale, esthioméne, chronic ulcer and elephantiasis of the genito-ano-rectal region, inflammatory stricture of the rectum.

London: Baillière, Tindall & Cox, 1933.

In this exhaustive review of the literature, Stannus considered all the conditions he discussed to be different manifestations of infection by the same organisms – the agent causing lymphogranuloma venereum. Includes historical summary and full bibliography.



Subjects: INFECTIOUS DISEASE › SEXUALLY TRANSMITTED DISEASES › History of Sexually Transmitted Diseases, INFECTIOUS DISEASE › SEXUALLY TRANSMITTED DISEASES › Lymphogranuloma Venereum, INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Lymphatic Filariasis (Elephantiasis)
  • 5222

Cultivation of the virus of lymphogranuloma inguinale and its use in therapeutic inoculation. Preliminary report.

J. Amer. Med. Assoc., 103, 408-09, 1934.


Subjects: INFECTIOUS DISEASE › SEXUALLY TRANSMITTED DISEASES › Lymphogranuloma Venereum
  • 5224

Complement-fixation test in lymphogranuloma venereum.

Proc. Soc. exp. Biol. (N.Y.), 44, 410-13, 1940.

Diagnosis of lymphogranuloma venereum by complement-fixation test. With G. W. Rake and M. F. Shaffer.



Subjects: INFECTIOUS DISEASE › SEXUALLY TRANSMITTED DISEASES › Lymphogranuloma Venereum, WOMEN, Publications by › Years 1900 - 1999
  • 5224.1

The vesicular test. Diagnostic method of infection by poradenic (lymphogranuloma inguinale)virus.

Amer. J. trop. Med., 21, 597-602, 1941.

Vesicular test for diagnosis of lymphogranuloma venereum.



Subjects: INFECTIOUS DISEASE › SEXUALLY TRANSMITTED DISEASES › Lymphogranuloma Venereum
  • 5225

The laboratory diagnosis of lymphogranuloma venereum.

J. clin. Path., 2, 241-49, 1949.

Skin-test antigen. With C. F. Barwell, E. J. King, and L. W. J. Bishop.



Subjects: INFECTIOUS DISEASE › SEXUALLY TRANSMITTED DISEASES › Lymphogranuloma Venereum
  • 5226

Die Litteratur über die venerischen Krankheiten von der ersten Schriften über Syphilis aus dem Ende des fünfzehnten Jahrhunderts bis zum Jahre 1889. (Supplement Band I. Enthält die Litteratur von 1889-99 und Nachträge aus früherer Zeit.) 5 vols.

Bonn: P. Hanstein, 18891900.

Reprinted Nieuwkoop, De Graaf 1966.



Subjects: BIBLIOGRAPHY › Bibliographies of Specific Diseases, INFECTIOUS DISEASE › SEXUALLY TRANSMITTED DISEASES › History of Sexually Transmitted Diseases
  • 5227

Die Geschichte der venerischen Krankheiten. 2 vols.

Bonn: P. Hanstein, 1895.

Vol. 1. Alterthum und Mittelalter. Vol. 2. Neuzeit.



Subjects: INFECTIOUS DISEASE › SEXUALLY TRANSMITTED DISEASES › History of Sexually Transmitted Diseases
  • 5227.1

Entwurf einer Geschichte der ansteckenden Geschlechtskrankheiten.

Handbuch der Haut- und Geschlechtskrankheiten, Berlin, 23, 264-603, 606-16, 632-42, 1931.


Subjects: DERMATOLOGY › History of Dermatology, INFECTIOUS DISEASE › SEXUALLY TRANSMITTED DISEASES › History of Sexually Transmitted Diseases
  • 5228

Epidemics I and III. In [Works] with English translation by W.H.S. Jones, 1, 139-287

London: Heinemann, 1923.

Hippocrates may be regarded as the first malariologist; he clearly and fully described the intermittent fevers; he was acquainted with seasonal and topographical variations in the distribution of malaria; and he recognized an association between marshes and fevers.



Subjects: EPIDEMIOLOGY, INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria
  • 5229

De semitertiana libri quatuor.

Frankfurt: apud haered. J. T. de Bry, 1624.

First extensive account of malaria.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria
  • 1826
  • 5230.1

Anastasis corticis Peruviae, seu chinae defensio

Genoa: typ. P. I. Calenzani, 1663.

A defence of the virtues of Jesuit's bark or Peruvian bark (cinchona, chinchona), the most celebrated specific remedy for malaria. It was obtained from the bark of several species of the genus Cinchona, of the Rubiaceae family, indigenous to the Western Andes mountains. Other terms referring to this preparation and its source were "Jesuit's Tree", "Jesuit's Powder" and "Pulvis Patrum". Bado includes evidence to show that “fever bark” was introduced into Spain in 1632. Digital facsimile from BnF Gallica at this link.



Subjects: COUNTRIES, CONTINENTS AND REGIONS › Peru, INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PHARMACOLOGY › PHARMACEUTICALS › Botanic Sources of Single Component Drugs › Cinchona Bark
  • 5231

Therapeutice specialis ad febres quasdam pemiciosas, inopinato, ac repente lethales, una vera china china, peculiare methodo ministrata, sanabiles

Modena: typ. B. Soliani, 1712.

Torti’s work finally established the specific nature of cinchona bark. His demonstration of its effectiveness in periodic over continuous fevers finally overthrew the doctrine of the common origin of all fevers. He is also credited with the introduction of the term “malaria”.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PHARMACOLOGY › PHARMACEUTICALS › Botanic Sources of Single Component Drugs › Cinchona Bark
  • 5232

De noxiis paludum effluviis, eorumque remediis.

Rome: typ. J. M. Salvioni, 1717.

Lancisi suggested that since malaria disappears after drainage it was due to some sort of poison emanating from marshes and possibly transmitted by mosquitoes. He planned a drainage scheme for marshy regions. His work included an early effort at medical cartography-- a map of the area between the gulfs of Astura and Terracina, south-southeast from Rome which identified twenty-six forested quarters ("quarti delle selve") and four ruined lands ("terre dirute").  The map also included directions of the major winds. Digital facsimile from the Internet Archive at this link.



Subjects: Cartography, Medical & Biological, EPIDEMIOLOGY, INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria
  • 5233

Recherches chimique sur les quinquinas.

Ann. Chim. Phys. (Paris), 15, 289-318, 337-65, 1820.

Isolation of quinine.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PHARMACOLOGY › PHARMACEUTICALS › Botanic Sources of Single Component Drugs › Cinchona Bark › Quinine
  • 5234

On the cryptogamous origin of malarious and epidemic fevers.

Philadelphia: Lea & Blanchard, 1849.

Although Hensinger in 1844 had suggested a parasite as the cause of malaria, Mitchell was the first to approach this theory in a scientific spirit. He was Professor of Medicine at Jefferson College, and the father of S. Weir Mitchell.



Subjects: EPIDEMIOLOGY, INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria
  • 1777
  • 5234.1

A systematic treatise, historical, etiological, and practical, on the principal diseases of the interior valley of North America as they appear in the Causcasian, African, Indian, and Esquimaux varieties of Its population. 2 vols.

Cincinnati, OH: W. B. Smith & Co & Philadelphia: Lippincott, Grambo & Co., 18501854.

This classical contribution to the social / medical history of North America includes the most important work on the natural history of malaria published up to that time. Digital facsimile of vol. 1 from the Internet Archive at this link. Vol. 2 was posthumously published as 2nd series, edited by S. Hanbury Smith & F. G. Smith, Philadelphia, 1854. Digital facsimile of vol. 2 from Google Books at this link.



Subjects: Bioclimatology, COUNTRIES, CONTINENTS AND REGIONS › United States , COUNTRIES, CONTINENTS AND REGIONS › United States › American Midwest, Geography of Disease / Health Geography, INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria
  • 5235

De la fièvre bilieuse mélanurique des pays chauds comparée avec la fièvre jaune.

Paris: A. Delahaye, 1874.

An important description of blackwater fever. Berenger-Féraud had experience of the disease in French West Africa.



Subjects: INFECTIOUS DISEASE, INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria
  • 5236

Un nouveau parasite trouvé dans le sang plusieurs malades atteints de fièvre palustre.

Bull. Soc, méd. Hôp. Paris. (Mém.), 2 sér., 17, 158-64, 1881.

Laveran first saw the malaria parasite on 20 October 1880; he at once recognized its significance. He named it Oscillaria malariae. English translation in Kean (No. 2268.1). Laveran also published a monograph on the discovery: Nature parasitaire des accidents de l’impaludisme. Description d’un nouveau parasite trouvé dans le sang…Paris: Baillière, 1881. See also his "Note sur un nouveau parasite trouvé dans le sang de plusieurs maladies atteints de fièvre palustre," Bulletin de l’Académie de Médicine, 2nd Series. 9 (1880) 1235-1236. 

English translations in Paludism. Translated by J.W. Martin. London: New Sydenham Society, 1893. Laveran was awarded the Nobel Prize in 1907.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PARASITOLOGY › Plasmodia, PARASITOLOGY › Plasmodia › P. vivax, P. falciparum, P. malariae, P. ovale, and P. knowlesi
  • 5237

Insects and disease - mosquitoes and malaria.

Pop. Sci. Monthly, (N. Y.), 23, 644-58, 1883.

The first reasoned argument in support of the belief of transmission of malaria by mosquitoes. King was an English-born American physician who witnessed the assassination of Abraham Lincoln in April, 1865, and as a bystander physician he was pressed into service during the assassination. He was also one of a few physicians who served in both the Confederate States Army and the United States Army during the American Civil War. Reproduced in part in Major, Classic descriptions of disease, 3rd ed., 1945, p. 104. Full text  of King's 1883 paper from Wikisource at this link.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria
  • 5238

Weitere Untersuchungen über die Malariainfection.

Fortschr. Med., 3, 787-806, 1885.

First accurate description of the malaria Plasmodium, discovered by Laveran in 1880. These writers were the first to adopt the name P. malariae.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PARASITOLOGY › Plasmodia › P. vivax, P. falciparum, P. malariae, P. ovale, and P. knowlesi
  • 5238.1

Zur Parasitologie des Blutes.

Biol. Zbl., 5, 529-37, 1885.

Discovery of malaria parasites in birds. See also Ann. Inst. Pasteur, 1890, 4, 427-31.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PARASITOLOGY › Plasmodia, VETERINARY MEDICINE › Veterinary Parasitology
  • 5239

Sull infezione malarica.

Arch. Sci. med. (Torino), 10, 109-35, 1886.

Description of the development of the parasite of quartan malaria. Golgi differentiated the tertian and quartan parasites by the periods of their respective developments.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PARASITOLOGY › Plasmodia › P. vivax, P. falciparum, P. malariae, P. ovale, and P. knowlesi
  • 5240

Sul ciclo evolutivo dei parassiti malarica nella febbre terzana.

Arch. Sci. med. (Torino), 13, 173-96, 1889.

Golgi showed that the parasite of quartan differs from that of tertian malarial fever. English translation in Kean (No. 2268.1).



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PARASITOLOGY › Plasmodia › P. vivax, P. falciparum, P. malariae, P. ovale, and P. knowlesi
  • 5240.1

Études sur l’infection malarique. Sur la variété parasitaire des corps en croissant de Laveran et sur les fièvres palustres qui en dérivent.

Arch. ital. Biol., 13, 262-86, 1890.

Canalis demonstrated and clearly differentiated Plasmodium falciparum from the species vivax and malariae.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PARASITOLOGY › Plasmodia › P. vivax, P. falciparum, P. malariae, P. ovale, and P. knowlesi
  • 5241

Malariaparasiten in den Vögeln.

Zbl. Bakt., 1891, 9, 403-09, 429-33, 461-67, 1891.

Confirmation of the work of Laveran.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PARASITOLOGY › Plasmodia › P. vivax, P. falciparum, P. malariae, P. ovale, and P. knowlesi
  • 5241.1

Ueber die Wirkung des Methylenblau bei Malaria.

Berl. klin. Wschr., 28, 953-56, 1891.

Guttmann and Ehrlich demonstrated methylene blue to be lethal in vitro for the malaria parasite – the beginning of Ehrlich’s work on chemotherapy.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PARASITOLOGY › Plasmodia › P. vivax, P. falciparum, P. malariae, P. ovale, and P. knowlesi, PHARMACOLOGY › Chemotherapy
  • 5242

K voprosu o parazitologii i terapii bolotnoi likhoradki. [Parasitology and treatment of malarial fever.]

St. Petersburg, Russia: I. N. Skovokhodoff, 1891.

Romanovsky made important studies of the malaria parasite and introduced a special stain for its demonstration. German version in St. Petersburger med. Wschr., 1891, 8, 297-302, 306-15. English translation in Kean (No. 2268.1).



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PARASITOLOGY, PARASITOLOGY › Plasmodia › P. vivax, P. falciparum, P. malariae, P. ovale, and P. knowlesi
  • 5243

Azione della chinina sui parasite malarici e sui corrispondente accessi febbrili.

Gazz. med. Pavia, 1, 34, 79, 106, 1892.

French translation in Arch. ital. Biol., 1892, 17, 456-71.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PARASITOLOGY › Plasmodia › P. vivax, P. falciparum, P. malariae, P. ovale, and P. knowlesi, PHARMACOLOGY › PHARMACEUTICALS › Botanic Sources of Single Component Drugs › Cinchona Bark › Quinine
  • 5244

Sulle febbre malariche estivo-autumnali.

Rome: E. Loescher, 1892.

A summary of the Italian work on malaria. English translation, 1894.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria
  • 5245

On the nature and significance of the crescentic and flagellated bodies in malarial blood.

Brit. med. J., 2, 1306-08, 1894.

Manson’s mosquito–malaria hypothesis. See also his Gulstonian Lectures in Lancet, 1896, 1, 695-98, 751-55, 831-33.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PARASITOLOGY › Plasmodia › P. vivax, P. falciparum, P. malariae, P. ovale, and P. knowlesi
  • 5246

On the flagellated form of the malarial parasite.

Lancet, 2, 1240-41, 1897.

MacCallum reported at a meeting of the British Association his observation of the mode of fertilization of the malarial parasite of birds; two months later he announced that he had found the same to hold good for the human parasite.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PARASITOLOGY › Plasmodia › P. vivax, P. falciparum, P. malariae, P. ovale, and P. knowlesi
  • 5247

On some peculiar pigmented cells found in two mosquitoes fed on malarial blood.

Brit med. J., 2, 1786-88, 1897.

Ross proved that the mosquito was responsible for the transmission of malaria. On 20 August 1897, he found Laveran’s Plasmodium in the stomach of the Anopheles mosquito after it had fed on the blood of malaria patients. See also the earlier paper in the same journal, 1897, 1, 251-55.



Subjects: EPIDEMIOLOGY, INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PARASITOLOGY › Plasmodia › P. vivax, P. falciparum, P. malariae, P. ovale, and P. knowlesi
  • 5248

Traité du paludisme.

Paris: Masson & Cie, 1898.


Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PARASITOLOGY › Plasmodia › P. vivax, P. falciparum, P. malariae, P. ovale, and P. knowlesi
  • 5249

On the haemocytozoa of birds.

J. exp. Med., 3, 79-101, 1898.

Demonstration of sexual conjugation in the malaria parasite. See also No. 5250.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PARASITOLOGY › Plasmodia › P. vivax, P. falciparum, P. malariae, P. ovale, and P. knowlesi, VETERINARY MEDICINE › Veterinary Parasitology
  • 5250

Notes on the pathological changes in the organs of birds infected with haemocytozoa.

J. exp. Med., 3, 103-16, 117-36, 1898.

MacCallum and Opie discovered the sexual phase of malaria parasites.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PARASITOLOGY › Plasmodia, VETERINARY MEDICINE › Veterinary Parasitology
  • 5251

The rôle of the mosquito in the evolution of the malarial parasite.

Lancet, 2, 488-89, 1898.

Ross provided the last link in the chain demonstrating the complete life-cycle of the parasite of bird malaria. He found that mosquitoes which had fed on malaria-infected birds, and which had allowed the parasites to develop and lodge in their salivary glands, could then infect healthy birds, which in turn became malarious. Ross was awarded the Nobel Prize for Medicine in 1902.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PARASITOLOGY › Plasmodia, VETERINARY MEDICINE › Veterinary Parasitology
  • 5252

Ciclo evolutivo della semilune nell’ Anopheles claviger.

Ann. Ig. sper., 1899, n.s. 9, 258-64, 1899.

Grassi and Bignami showed that the Plasmodium undergoes its sexual phase only in the Anopheles mosquito.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PARASITOLOGY, PARASITOLOGY › Plasmodia
  • 5252.1

Studi di uno zoologo sulla malaria.

Rome: V. Salviucci, 1900.

Includes the best illustrations of the various stages of the malaria parasite published up to that time.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PARASITOLOGY › Plasmodia › P. vivax, P. falciparum, P. malariae, P. ovale, and P. knowlesi
  • 5252.2

Experimental proof of the mosquito-malaria theory.

Brit. med. J., 2, 949-51, 1900.

In a classic demonstration Manson allowed infected mosquitoes from Rome to bite a volunteer (his son) in London, who developed malaria 15 days later with tertian parasites in the blood, and who was cured by quinine.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PARASITOLOGY › Plasmodia › P. vivax, P. falciparum, P. malariae, P. ovale, and P. knowlesi
  • 5253

Note on a simple and rapid method of producing Romanowsky staining in malarial and other blood films.

Brit. med. J., 2, 757-58, 1901.

“Leishman’s stain”, a modification of that introduced by Romanovsky in 1891.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria
  • 5254

Studien über krankheitserregende Protozoen. II. Plasmodium vivax (Grassi & Feletti), der Erreger des Tertianfiebers beim Menschen.

Arb. k. GesundhAmte, 19, 169-250, 1903.

Confirmation of the work of Ross and of Grassi.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PARASITOLOGY › Plasmodia › P. vivax, P. falciparum, P. malariae, P. ovale, and P. knowlesi
  • 5255

Intracorpuscular conjugation in the malarial plasmodia and its significance.

Amer. Med., 10, 982-86, 1029-32, 1905.

Demonstration of the existence of malarial carriers.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PARASITOLOGY › Plasmodia › P. vivax, P. falciparum, P. malariae, P. ovale, and P. knowlesi
  • 5255.1

The cultivation of malaria plasmodia (Plasmodium vivax and Plasmodium falciparum) in vitro.

J. exp. Med.,16, 567-79, 1912.

Cultivation of the malaria parasite.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PARASITOLOGY › Plasmodia › P. vivax, P. falciparum, P. malariae, P. ovale, and P. knowlesi
  • 5255.2

A new malaria parasite of man.

Ann. trop. Med. Parasit., 16, 383-88, 1922.

Plasmodium ovale described.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PARASITOLOGY › Plasmodia › P. vivax, P. falciparum, P. malariae, P. ovale, and P. knowlesi
  • 5256

Die Wirkung des Plasmochins auf die Vogelmalaria.

Arch. Schiffs- u. Tropenhyg., 30, Beihefte, 311-18; 31, Beihefte, 48-58, 19261927.

Introduction of plasmoquine (pamaquin) in the treatment of malaria.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PHARMACOLOGY › PHARMACEUTICALS › Antimalarial Drugs
  • 5256.1

Studies in malaria, with special references to treatment. Part IX. Plasmoquine in the treatment of malaria.

Indian J. med. Res., 16, 159-77, 1928.

Clinical trials of pamaquin.



Subjects: COUNTRIES, CONTINENTS AND REGIONS › India, INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PHARMACOLOGY › PHARMACEUTICALS › Antimalarial Drugs
  • 5257

Zur Weiterentwicklung synthetisch dargestellter Malariamittel. I. Ueber die chemotherapeutische Wirkung des Atebrin.

Dtsch. med. Wschr., 58, 530-31, 1932.

Introduction of atebrin (mepacrine, quinacrine).



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PHARMACOLOGY › PHARMACEUTICALS › Antimalarial Drugs
  • 5258

Exo-erythrocytic schizogony in Plasmodium gallinaceum Brumpt, 1935.

Parasitology, 30, 128-39, 1938.

The term “exo-erythrocytic stage” introduced to describe the unpigmented schizonts found in tissue cells. The parasite Plasmodium gallincaceum described by Alexandre Joseph Emile Brumpt causes malaria in poultry.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PARASITOLOGY › Plasmodia, VETERINARY MEDICINE › Veterinary Parasitology
  • 5259

Klinische und parasitologische Befunde und chemotherapeutische Ergebnisse bei der Hühnermalaria.

Arch. Schiffs-u. Tropenhyg., 44, 257-75, 1940.

Discovery of the developmental forms of P. gallinaceum in the incubation period.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PARASITOLOGY › Plasmodia, VETERINARY MEDICINE › Veterinary Parasitology, WOMEN, Publications by › Years 1900 - 1999
  • 5259.1

The form of Plasmodium, gallinaceum present in the incubation period of the infection.

Indian J. med. Res., 28, 273-76, 1940.

Independently of Mudrow, H. E. Shortt, K. P. Menon, and P. V. Seetharama Iyer found pre-erythrocytic forms of P. gallinaceum in the tissues.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PARASITOLOGY › Plasmodia, VETERINARY MEDICINE › Veterinary Parasitology
  • 5259.2

The development of Plasmodium gallinaceum from sporozoite to erythrocytic trophozoite.

J. infect. Dis., 75, 231-49, 1944.

First detailed account of the full cycle of development of the avian malaria parasite P. gallinaceum.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PARASITOLOGY › Plasmodia, VETERINARY MEDICINE › Veterinary Parasitology
  • 5260

Studies on synthetic antimalarial drugs.

Ann. trop. Med. Parasit., 39, 139-64, 208-16, 1945.

F. H. S. Curd, D. G. Davey, and F. L. Rose synthesized proguanil (“paludrine”) and first tested it in avian malaria.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PHARMACOLOGY › PHARMACEUTICALS › Antimalarial Drugs
  • 5261

Studies on synthetic antimalarial drugs. XIII. Results of a preliminary investigation of the therapeutic action of 4888 (paludrine) on acute attacks of benign tertian malaria.

Ann. trop. Med. Parasit., 39, 225-31, 1945.

First use of proguanil in human malaria. With B. G. Maegraith, J. D. King, R. H. Townsend, T. H. Davey, and R. E. Havard.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PHARMACOLOGY › PHARMACEUTICALS › Antimalarial Drugs
  • 5261.1

Chloroquine for treatment of acute attacks of vivax malaria.

J. Amer. med. Assoc., 131, 963-67, 1946.

Harry Most led the development of chloroquine for use in treating American troops suffering from malaria. At the beginning of the American involvement in the war there were more American casualties from malaria than from enemy fire, but by the end of the campaign in the Pacific, at least partly because of the administration of chloroquine, malaria was largely under control.

Clinical trials of chloroquine. With  Charles A. Kane,  Edmund F. Schroeder, and Joseph M. Hayman, Jr. See also J. Amer. med Assoc., 1946, 130, 1069.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PARASITOLOGY › Plasmodia › P. vivax, P. falciparum, P. malariae, P. ovale, and P. knowlesi, PHARMACOLOGY › PHARMACEUTICALS › Antimalarial Drugs
  • 5261.2

Pentaquine (Sn-13,276), a therapeutic agent effective in reducing the relapse rate in vivax malaria.

J. clin. Invest., 27, No. 3, pt. 2, 25-33, 1948.

Clinical trials of pentaquine. With B. Craige, R. Jones, C. M. Whorton, T. N. Pullman, and L. Eichelberger.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PARASITOLOGY › Plasmodia › P. vivax, P. falciparum, P. malariae, P. ovale, and P. knowlesi, PHARMACOLOGY › PHARMACEUTICALS › Antimalarial Drugs
  • 5262

The pre-erythrocytic stage of mammalian malaria.

Brit. med. J., 1, 192-94, 1948.

Demonstration of the pre-erythrocytic stage of P. cynomolgi in the monkey. With P. C. C. Garnham and B. Malamos. Preliminary communication in Nature (Lond.), 1948, 161, 126.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PARASITOLOGY › Plasmodia, VETERINARY MEDICINE › Veterinary Parasitology
  • 5262.1

The pre-erythrocytic stage of human malaria Plasmodium vivax.

Brit. med. J., 1, 547 (only), 1948.

With P. C. C. Garnham, G. Covell, and P. G. Shute.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PARASITOLOGY › Plasmodia › P. vivax, P. falciparum, P. malariae, P. ovale, and P. knowlesi
  • 5262.2

The pre-erythrocytic stage of Plasmodium falciparum. A preliminary note.

Brit. med. J., 2, 1006-08, 1949.

With N. H. Fairley, G. Covell, P. G. Shute, and P. C. C. Garnham. See also Trans. roy. Soc. trop. Med. Hyg., 1951, 44, 405-19.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PARASITOLOGY › Plasmodia › P. vivax, P. falciparum, P. malariae, P. ovale, and P. knowlesi
  • 5262.3

Primaquine, S.N. 13,272, a new curative agent in vivax malaria: a preliminary report.

J. nat. Malaria Soc., 9, 285-92, 1950.

Introduction of primaquine.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PHARMACOLOGY › PHARMACEUTICALS › Antimalarial Drugs
  • 5262.4

2:4-Diaminopyrimidines – a new series of antimalarials.

Brit. J. Pharmacol., 6, 185-200, 1951.

Preparation and laboratory tests of pyrimethamine. With L. G. Goodwin, G. H. Hutchings, I. M. Rollo, and P. B. Russell.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PHARMACOLOGY › PHARMACEUTICALS › Antimalarial Drugs
  • 5262.5

A 2:4-diamino pyrimidine in the treatment of proguanil-resistant laboratory malarial strains.

Nature (Lond.), 168, 332-33, 1951.

Pyrimethamine (daraprim).



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria, PHARMACOLOGY › PHARMACEUTICALS › Antimalarial Drugs
  • 5263

Malaria and Greek history. To which is added the history of Greek therapeutics and the malaria theory by E.T. Withington.

Manchester: Manchester University Press, 1909.

The view is put forward by the writer that malarial infection was the cause of the decadence of the Greeks. Digital facsimile from the Internet Archive at this link.



Subjects: ANCIENT MEDICINE › Greece › History of Ancient Medicine in Greece, INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria › History of Malaria
  • 5264

The history of malaria in the Roman Campagna from ancient times. Edited and enlarged by Anna Celli-Fraentzel.

London: John Bale, 1933.

Reprinted New York, 1977.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria › History of Malaria
  • 5264.1

Blackwater fever, a historical survey and summary of observations made over a century.

Liverpool: University Press, 1937.


Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria › History of Malaria
  • 5264.2

The conquest of malaria.

London: William Heinemann, 1950.


Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria › History of Malaria
  • 5264.3

Man’s mastery of malaria.

London: Oxford University Press, 1955.

Heath Clark Lectures, 1953.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Malaria › History of Malaria
  • 2148
  • 5265

The navy-surgeon, or a practical system of surgery.

London: C. Ward and R. Chandler, 1734.

Atkins was an English naval surgeon. His book includes some useful case reports and contains the first English description of African trypanosomiasis.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Triatomine Bug-Borne Diseases › Chagas Disease (American Trypanosomiasis) , MILITARY MEDICINE & HYGIENE › Navy
  • 5266

An account of the native Africans in the neighbourhood of Sierra Leone; to which is added, an account of the present state of medicine among them. 2 vols.

London: John Hatchard & John Mawman, 1803.

In his travels in Africa, Winterbottom, physician to the Colony of Sierra Leone (now Republic of Sierra Leone) on the west coast of Africa, saw sleeping sickness, which he described in vol. 2, pp. 29-31, as a species of lethargy. He also noticed that slave-dealers would not buy slaves whose neck glands showed signs of enlargement. Digital facsimile of vol. 1 from the Internet Archive at this link;  digital facsimile of vol. 2 from the Hathi Trust at this link.;



Subjects: AFRICAN AMERICANS & MEDICINE & BIOLOGY, COUNTRIES, CONTINENTS AND REGIONS › Africa, COUNTRIES, CONTINENTS AND REGIONS › Sierra Leone, INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Tsetse Fly-Borne Diseases, INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Tsetse Fly-Borne Diseases › Sleeping Sickness (African Trypanosomiasis), Slavery and Medicine, TROPICAL Medicine , VOYAGES & Travels by Physicians, Surgeons & Scientists
  • 5267

Observations on the disease lethargus: with cases and pathology.

Lond. med. Gaz., 26, 970-76, 1840.

Clarke left a detailed account of African trypanosomiasis; he saw cases of the disease while serving as a colonial surgeon at Sierra Leone, and named it “narcoleptic dropsy”.



Subjects: COUNTRIES, CONTINENTS AND REGIONS › Africa, INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Triatomine Bug-Borne Diseases › Chagas Disease (American Trypanosomiasis)
  • 5267.1

Ueber ein Entozoon im Blute von Salmo fario.

Arch. Anat. Physiol. wiss. Med., 435-36, 1841.

Valentin was the first to discover a trypanosome; this was in a salmon. English translation in Kean (No. 2268.1).



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Triatomine Bug-Borne Diseases › Chagas Disease (American Trypanosomiasis) , PARASITOLOGY › Trypanosoma
  • 5268

Recherches et observations sur une nouvelle espèce d’hématozoaire, Trypanosoma sanguinis.

C. R. Acad. Sci. (Paris),17, 1134-36, 1843.

Gruby discovered trypanosomes in the frog. He first suggested the name “trypanosome” to describe the parasite.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Triatomine Bug-Borne Diseases › Chagas Disease (American Trypanosomiasis) , PARASITOLOGY › Trypanosoma, VETERINARY MEDICINE › Veterinary Parasitology
  • 5269

Missionary travels and researches in South Africa.

London: John Murray, 1857.

Livingstone gave an accurate account of the tsetse fly Glossina morsitans and of the disease in cattle following its bite (see pp. 80-83; picture of the tsetse fly on p. 571). In his time the bite of the fly was thought to be (and perhaps was) harmless to man.



Subjects: COUNTRIES, CONTINENTS AND REGIONS › Africa, INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Tsetse Fly-Borne Diseases › Sleeping Sickness (African Trypanosomiasis), TROPICAL Medicine , VOYAGES & Travels by Physicians, Surgeons & Scientists
  • 5270

Arsenic as a remedy for the tsetse bite.

Brit. med. J., 360-61, 1858.

Livingstone was probably the first to administer arsenic for the treatment of “nagana”, a disease of horses caused by trypanosomes. This followed a suggestion by James Braid. Digital facsimile from PubMedCentral at this link.



Subjects: COUNTRIES, CONTINENTS AND REGIONS › Africa, INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Tsetse Fly-Borne Diseases › Sleeping Sickness (African Trypanosomiasis), TROPICAL Medicine , VETERINARY MEDICINE
  • 5270.1

The microscopic organisms found in the blood of man and animals, and their relation to disease.

Ann. rep. sanit. Comm. India (1877), 14, Appendix B, 157-208, 1878.

First description of a trypanosome (T. lewisi) in a mammal. Seoarate edition in book form with the same title: Calcutta: Office of the Superintendent of Government Printing, 1879.



Subjects: COUNTRIES, CONTINENTS AND REGIONS › India, INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Triatomine Bug-Borne Diseases › Chagas Disease (American Trypanosomiasis) , PARASITOLOGY › Trypanosoma
  • 5271

On a horse disease in India known as “surra”, probably due to a haematozoon.

Vet. J., 13, 1-10, 82-88, 180-200, 326-33, 1881.

While serving in India as a veterinary surgeon, Evans discovered parasites in the blood of horses suffering from surra; this was the first pathogenic trypanosome to be described.



Subjects: COUNTRIES, CONTINENTS AND REGIONS › India, INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Triatomine Bug-Borne Diseases › Chagas Disease (American Trypanosomiasis) , VETERINARY MEDICINE
  • 5272

Étude sur les parasites du sang chez les paludiques.

C. R. Soc. Biol. (Paris), 43, 39-50, 1891.

Nepveu, whilst in Algeria, was the first to see trypanosomes in human blood.



Subjects: COUNTRIES, CONTINENTS AND REGIONS › Algeria, INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Triatomine Bug-Borne Diseases › Chagas Disease (American Trypanosomiasis) , PARASITOLOGY › Trypanosoma, TROPICAL Medicine
  • 5273

Preliminary report on the tsetse fly disease or nagana, in Zululand.

Durban, South Africa: Bennett & Davis, 1895.

In 1895 Bruce found that nagana, the tsetse fly disease of Zululand, was due to a trypanosome (T. brucei). He described a hematozoon in the blood of the affected animals that had not been previously described.

Digital facsimile from the Internet Archive at this link.



Subjects: COUNTRIES, CONTINENTS AND REGIONS › South Africa, INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Tsetse Fly-Borne Diseases › Sleeping Sickness (African Trypanosomiasis), TROPICAL Medicine
  • 5274

Some clinical notes on a European patient in whose blood a trypanosoma was observed.

J. trop. Med. Hyg., 5, 261-63, 1902.

In 1901 Forde saw (but did not at first recognize as such) trypanosomes in the blood of a patient in Gambia. (See No. 5275.)



Subjects: COUNTRIES, CONTINENTS AND REGIONS › Africa, INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Triatomine Bug-Borne Diseases › Chagas Disease (American Trypanosomiasis) , PARASITOLOGY › Trypanosoma
  • 5275

Preliminary note upon a trypanosome occurring in the blood of man.

Thompson Yates Lab. Rep., 4, 455-68, 1902.

Dutton was the first to recognize human trypanosomiasis. He saw Forde’s patient (see No. 5274) and named the trypanosome T. gambiense. Sleeping sickness itself has been referred to as “Dutton’s disease”. The first announcement was in the form of a telegram to Ronald Ross, published in Brit. med. J., 1902, 1, 42.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Tsetse Fly-Borne Diseases › Sleeping Sickness (African Trypanosomiasis), PARASITOLOGY › Trypanosoma
  • 5276

On the discovery of a species of trypanosoma in the cerebrospinal fluid of cases of sleeping sickness.

Proc. roy. Soc., 71, 501-08, 1903.

While in Uganda, Castellani discovered T. gambiense in human cerebrospinal fluid. A paper in Notes Rec. roy. Soc., 1973, 23, 93-110, discounts Castellani’s claim that although he first discovered trypanosomes in the cerebrospinal fluid of sleeping sickness patients, he failed to appreciate the etiological significance of this until it was brought home to him by Sir David Bruce.



Subjects: COUNTRIES, CONTINENTS AND REGIONS › Uganda, INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Tsetse Fly-Borne Diseases › Sleeping Sickness (African Trypanosomiasis), PARASITOLOGY › Trypanosoma
  • 5277

Reports of the Sleeping Sickness Commission of the Royal Society, 1903-1912. 17 pts.

London: H. M. Stationery Office, 19031919.

Bruce and D.N. Nabarro were sent to Africa by the Royal Society to study sleeping sickness, and in their report they showed that the tsetse fly was the vector of trypanosomiasis. They also found that Gambia fever and sleeping sickness were two stages of the same infection.



Subjects: COUNTRIES, CONTINENTS AND REGIONS › Africa, INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Tsetse Fly-Borne Diseases › Sleeping Sickness (African Trypanosomiasis), TROPICAL Medicine
  • 5278

Trypanosomes et trypanosomiases.

Paris: Masson & Cie, 1904.

Laveran and Mesnil discovered that trypanosomes could be maintained indefinitely in rats and mice by serial passage.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Tsetse Fly-Borne Diseases › Sleeping Sickness (African Trypanosomiasis), PARASITOLOGY › Trypanosoma
  • 5279

Report on trypanosomes, trypanosomiasis, and sleeping sickness, being an experimental investigation into their pathology and treatment.

London: Williams & Norgate, 1905.

Thomas and Breinl discovered that arsanilic acid, was more potent in the treatment of laboratory trypanosomiasis than arsenic in inorganic form. As a crystalline powder it was introduced medically as Atoxyl. Thomas and Breinl recommended high doses, given continously for human typanosomiasis. The above is Memoir XVI of the Liverpool School of Tropical Medicine. The drug was soon found to be prohbitively toxic for human use and taken off the market.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Tsetse Fly-Borne Diseases › Sleeping Sickness (African Trypanosomiasis), PARASITOLOGY › Trypanosoma, PHARMACOLOGY › PHARMACEUTICALS › Antiparasitic Drugs, TROPICAL Medicine
  • 5280

Traitement des trypanosomiases par les “couleurs de benzidine”.

Ann. Inst. Pasteur, 20, 417-48, 513-38, 1906.

Introduction of trypan-blue in the treatment of trypanosomiasis. Second paper by Mesnil and Nicolle.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Tsetse Fly-Borne Diseases › Sleeping Sickness (African Trypanosomiasis), PHARMACOLOGY › PHARMACEUTICALS › Antiparasitic Drugs
  • 5281

Chemotherapeutische Trypanosomen-Studien.

Berl. klin. Wschr., 44, 233-36, 280-83, 310-14, 341-44, 1907.

The first account of induced microbial drug resistance. Ehrlich encountered induced drug resistance in microbes while researching arsenical preparations as cures for sleeping sickness and other trypanosome-caused illnesses. His paper, delivered as a lecture on Feb. 13, 1907, “explained how the widely varying stains of trypanosomes, which at first reacted with great sensitivity to chemotherapeutic agents, gradually became drug resistant and how this property was passed on to their offspring for many generations” (Bäumler, Paul Ehrlich, p. 128). Includes an account of “Trypanrot”, by which Ehrlich succeeded in curing experimental trypanosomiasis. It was his work on this subject which led Ehrlich eventually to the production of Salvarsan. He shared the Nobel Prize for Medicine with Metchnikoff in 1908.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Tsetse Fly-Borne Diseases, INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Tsetse Fly-Borne Diseases › Sleeping Sickness (African Trypanosomiasis), PARASITOLOGY › Trypanosoma, PHARMACOLOGY › Drug Resistance, PHARMACOLOGY › PHARMACEUTICALS › Antiparasitic Drugs, PHARMACOLOGY › PHARMACEUTICALS › Chemotherapeutic Agents
  • 5282

Further results of the experimental treatment of trypanosomiasis in rats.

Proc. roy. Soc. B., 80, 1-12, 1908.

Trial of antimony in the treatment of trypanosomiasis.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Triatomine Bug-Borne Diseases › Chagas Disease (American Trypanosomiasis) , PHARMACOLOGY › PHARMACEUTICALS › Antiparasitic Drugs, VETERINARY MEDICINE › Veterinary Parasitology
  • 5283

Nova tripanozomiaze humana. Estudos sobre a morfolojia e o ciclo evolutivo do Schizotrypanum cruzi n.gen., n.sp., ajente etiolojico de nova entidade morbida do homen.

Mem. Inst. Osw. Cruz, 1, 159-218, 1909.

Chagas discovered T. cruzi, causal organism in American trypanosomiasis (“Chagas’s disease”). Partial English translation in Kean (No. 2268.1).



Subjects: COUNTRIES, CONTINENTS AND REGIONS › Brazil, INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Triatomine Bug-Borne Diseases, INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Triatomine Bug-Borne Diseases › Chagas Disease (American Trypanosomiasis) , Latin American Medicine, PARASITOLOGY › Trypanosoma
  • 5283.1

Positive Infektionsversuche mit Trypanosoma brucei durch Glossina palpalis.

Dtsch. med. Wschr., 35, 469-70, 1909.

Glossina was believed to transmit Trypanosoma mechanically to the new host until Kleine showed that the latter undergoes a developmental cycle in Glossina. English translation in Kean (No. 2268.1).



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Tsetse Fly-Borne Diseases › Sleeping Sickness (African Trypanosomiasis), PARASITOLOGY › Trypanosoma
  • 5284

Le mécanisme d’action des dérivés arsenicaux dans les trypanosomiases.

Ann. Inst. Pasteur, 23, 604-43, 1909.

A study of the action of atoxyl and arsacétine.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Tsetse Fly-Borne Diseases › Sleeping Sickness (African Trypanosomiasis)
  • 5285

On the peculiar morphology of a trypanosome from a case of sleeping sickness and the possibility of its being a new species.

(T. rhodesiense). Proc. roy. Soc. B., 83, 28-33, 1910.

T. rhodesiense discovered.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Tsetse Fly-Borne Diseases › Sleeping Sickness (African Trypanosomiasis), PARASITOLOGY › Trypanosoma
  • 5285.1

Contribuiçao para o estudo da anatomia patolojica da “molestia de Carlos Chagas”.

Mem. Inst. Osw. Cruz, 3, 276-94, 1911.

Demonstration of the mode of reproduction of T. cruzi. Text in Portuguese and German. See also the paper by Chagas in pp. 219-75 of the same journal.



Subjects: COUNTRIES, CONTINENTS AND REGIONS › Brazil, INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Triatomine Bug-Borne Diseases › Chagas Disease (American Trypanosomiasis)
  • 5285.2

On the transmission of human trypanosomes by Glossina morsitans, Westw.; and on the occurrence of human trypanosomes in game.

Ann. trop. Med. Parasit., 6, 1-23, 1912.

Glossina morsitans shown to be the transmitting fly of T. rhodesiense.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Triatomine Bug-Borne Diseases › Chagas Disease (American Trypanosomiasis)
  • 5285.3

Le trypanosoma cruzi évolue chez Conorhinus megistus, Cimex lectularius, Cimex Boueti et Ornithodorus moubata. Cycle évolutif de ce parasite.

Bull. Soc. Path. exot., 5, 360-64, 1912.

Life cycle of T. cruzi described. English translation in Kean (No. 2268.1).



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Triatomine Bug-Borne Diseases › Chagas Disease (American Trypanosomiasis) , PARASITOLOGY, PARASITOLOGY › Trypanosoma
  • 5286

Ueber chemotherapeutische Versuche mit “205 Bayer”, einen neuen trypanoziden Mittel von besonderer Wirkung.

Berl. klin. Wschr., 57, 821-23, 1920.

Introduction of “Bayer 205” (germanin, suramin, naphuride).



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Triatomine Bug-Borne Diseases › Chagas Disease (American Trypanosomiasis) , PHARMACOLOGY › PHARMACEUTICALS › Antiparasitic Drugs
  • 5287

Studies on the treatment of human trypanosomiasis with tryparsamide (the sodium salt of N-phenylglycineamide-p-arsonic acid).

J. exp. Med., 34, Suppl., 1-104, 1921.

Introduction of tryparsamide in the treatment of trypanosomiasis.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Triatomine Bug-Borne Diseases › Chagas Disease (American Trypanosomiasis) , PHARMACOLOGY › PHARMACEUTICALS › Antiparasitic Drugs, WOMEN, Publications by › Years 1900 - 1999
  • 5288

Chimiothérapie des trypanosomiasis.

Paris méd., 49, 501-08, 1923.

Introduction of moranyl (“Foumeau 309”).



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Triatomine Bug-Borne Diseases › Chagas Disease (American Trypanosomiasis) , PHARMACOLOGY › PHARMACEUTICALS › Antiparasitic Drugs, PHARMACOLOGY › PHARMACEUTICALS › Chemotherapeutic Agents
  • 5289

Essai de prophylaxie des trypanosomiases par des dérivés phénylarsiniques administré

per os. Bull. Soc. Path. exot., 19, 737-46, 1926.

First attempt to induce prophylaxis by chemical means in trypanosomiasis. With S. Nicolau and I. Galloway.



Subjects: IMMUNOLOGY › Immunization, INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Triatomine Bug-Borne Diseases › Chagas Disease (American Trypanosomiasis) , PHARMACOLOGY › PHARMACEUTICALS › Antiparasitic Drugs
  • 5289.1

Factors that may influence the infection rate of Glossina palpalis with Trypanomosoma gambiense. 1. The age of the fly at the time of the infected feed.

Ann. trop. Med. Parasit., 52, 385-90, 1958.

Wijers showed that the tsetse fly is infected during its first or second blood meal, but not afterwards, information of considerable importance in determining the criteria for the transmission of trypanosomiasis.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Tsetse Fly-Borne Diseases › Sleeping Sickness (African Trypanosomiasis), PARASITOLOGY › Trypanosoma
  • 5289.2

Bibliography of trypanosomiasis.

London: Sleeping Sickness Commission, Royal Society, 1909.

Subject index…with additional references and corrections, 1910.



Subjects: BIBLIOGRAPHY › Bibliographies of Specific Diseases, INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Tsetse Fly-Borne Diseases › Sleeping Sickness (African Trypanosomiasis)
  • 5289.3

Chagas’s disease (South American trypanosomiasis). A bibliography compiled from Sleeping Sickness Bureau Bulletin 1908-1912, and Tropical Diseases Bulletin, 1912-1970.

London: Bureau of Hygiene and Tropical diseases, 1970.

Supplement to Trop. Dis. Bull., vol. 67.



Subjects: BIBLIOGRAPHY › Bibliographies of Specific Diseases, INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Triatomine Bug-Borne Diseases › Chagas Disease (American Trypanosomiasis) , TROPICAL Medicine
  • 5289.4

A bibliography on Chagas’s disease (1909-1969). By Margaret C. Olivier, Louis J. Olivier, Dorothy B. Segal.

Washington, DC: U.S. Government Printing Office, 1972.

Index-Catalogue of Medical and Veterinary Zoology, Special Publication No. 2.



Subjects: BIBLIOGRAPHY › Bibliographies of Specific Diseases, INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Triatomine Bug-Borne Diseases › Chagas Disease (American Trypanosomiasis) , WOMEN, Publications by › Years 1900 - 1999
  • 5290

Natural history of Aleppo and parts adjacent.

London: A. Millar, 1756.

Includes (Chap, iv) a good account of “Aleppo boil”, which Russell found to be endemic in Aleppo. Digital facsimile from the Internet Archive at this link.



Subjects: COUNTRIES, CONTINENTS AND REGIONS › Syria, DERMATOLOGY, INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Sandfly-Borne Diseases, INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Sandfly-Borne Diseases › Leishmaniasis, TROPICAL Medicine , VOYAGES & Travels by Physicians, Surgeons & Scientists
  • 5291

Sur la pyrophlyctide endémique, ou pustule d’Aleppo.

Rev. méd. Franç., étrang., n.s. 3, 62-71, 1829.

Important description of “Aleppo boil”, furunculosis orientalis.



Subjects: COUNTRIES, CONTINENTS AND REGIONS › Syria, DERMATOLOGY, INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Sandfly-Borne Diseases › Leishmaniasis, TROPICAL Medicine
  • 5292

Kala azar.

Proc. Govt. Bengal in the Med. Dept., No. 52, pp. 31-33, 1870.

Kala azar is mentioned briefly in the Proceedings in 1869 (No. 34, p. 19) but the above is the first full description, given by Briscoe in a report dated 1 Dec 1869.



Subjects: COUNTRIES, CONTINENTS AND REGIONS › India, INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Sandfly-Borne Diseases › Leishmaniasis
  • 5293

On the presence of peculiar parasitic organisms in the tissue of a specimen of Delhi boil.

Sci. Med. mem. Off. Army India, [1884], 1, 21-31, 1885.

Cunningham saw and described bodies in Delhi boil; these were almost certainly Leishman–Donovan bodies.



Subjects: COUNTRIES, CONTINENTS AND REGIONS › India, DERMATOLOGY, INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Sandfly-Borne Diseases › Leishmaniasis
  • 5293.1

Beitrag zum klinischen und bacteriologischen Studium der brasilianischen Framboesie oder “Boubas”.

Arch. Dermat. Syph. (Wien), 33, 3-28, 1895.

“Breda’s disease” – Brazilian yaws. English translation New Sydenham Society, 1897.



Subjects: COUNTRIES, CONTINENTS AND REGIONS › Brazil, DERMATOLOGY, INFECTIOUS DISEASE › Treponematoses › Yaws, INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Sandfly-Borne Diseases › Leishmaniasis
  • 5294

On sart sore.

Voenno med. Zhur., 76, 925-41, 1898.

First description of the protozoon later named Leishmania tropica. The paper is in Russian; for a translation, see C. A. Hoare, in Trans. roy. Soc. trop. Med. Hyg., 1938, 32, 78-90.



Subjects: COUNTRIES, CONTINENTS AND REGIONS › Russia, INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Sandfly-Borne Diseases › Leishmaniasis, PARASITOLOGY › Protozoa
  • 5295

On the possibility of the occurrence of trypanosomiasis in India.

Brit. med. J., 1, 1252-54; 2, 1376-77, 1903.

An organism found by Leishman in 1900 was later described by him as possibly a trypanosome. C. Donovan found the same organism in blood in July 1903. The name Leishmania donovani (Leishman-Donovan bodies) was later attached to these organisms.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Sandfly-Borne Diseases › Leishmaniasis, PARASITOLOGY › Trypanosoma
  • 5296

On the possibility of the occurrence of typanosomiasis in India.

Brit. med. J., 2, 79, 1903.

Leishimania donovani,  independently discovered by two British medical officers William Boog Leishman in Netley, England, and Donovan in Madras, India, in 1903. However, the correct taxonomy was provided by Ronald Ross. See No. 5295 and Med. Hist., 1983, 27, 203-13.



Subjects: COUNTRIES, CONTINENTS AND REGIONS › India, INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Sandfly-Borne Diseases › Leishmaniasis
  • 5297

Protozoa in a case of tropical ulcer (Delhi sore).

J. med. Res.,10, 472-82, 1903.

Wright found Leishmania tropica in Delhi sore. He was unaware of Borovskii’s paper (No. 5294).



Subjects: COUNTRIES, CONTINENTS AND REGIONS › India, DERMATOLOGY, INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Sandfly-Borne Diseases › Leishmaniasis, TROPICAL Medicine
  • 5298

Note on the nature of the parasitic bodies found in tropical splenomegaly.

Brit. med. J., 1, 303, 1904.


Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Sandfly-Borne Diseases › Leishmaniasis, PARASITOLOGY, TROPICAL Medicine
  • 5299

Note on the occurrence of Leishman–Donovan bodies in “cachexial fevers” including kala-azar.

Brit. med. J., 1, 1249-51, 1904.

Rogers demonstrated the Leishman–Donovan bodies in kala-azar. See also the same journal, 1904, 2, 645-50. At about the same time Bentley reported similar findings in India.



Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Sandfly-Borne Diseases › Leishmaniasis, Latin American Medicine, PARASITOLOGY, TROPICAL Medicine
  • 5299.1

L’ulcère de Bauru ou le bouton d’orientau Brésil.

Bull. Soc. Path. exot., 2, 252-54, 1909.

Muco-cutaneous leishmaniasis of South America. English translation in Kean (No. 2268.1).



Subjects: COUNTRIES, CONTINENTS AND REGIONS › Brazil, DERMATOLOGY, INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Sandfly-Borne Diseases › Leishmaniasis