An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to Circa 2020 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

15429 entries, 13282 authors and 1897 subjects. Updated: October 23, 2021

Browse by Entry Number 3000–3099

157 entries
  • 3000

Ueber die konservative Behandlung der Varicen.

Med. Klin., 12, 897-98, 1916.

Injection treatment of varicose veins was introduced by Linser.



Subjects: VASCULAR SURGERY
  • 3001

Du traitement des varices par les injection coagulantes, concentrées de sels de quinine.

Soc. méd. mil. franç. Bull., 15, 169-71, 1921.

Injection of quinine urethane for the treatment of varicose veins.



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Venous Disease
  • 3002

Traitement des varices par les injections phlébo-sclérosantes du salicylate de soude.

Gaz. Hôp. Paris, 95, 1573-75, 1922.

Introduction of sodium salicylate injections for the treatment of varicose veins. With J. Paraf and J. Lermoyez.



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Venous Disease
  • 3003

Die Behandlung der Krampfadern mit intravarikösen Kochsalzinjektionen.

Derm. Wschr., 81, 1345-51, 1925.

Sodium chloride first used in the injection treatment of varicose veins.



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Venous Disease
  • 3004

Die Calorose als Verödungsmittel varikös entarteter Venen.

Wien. klin. Wschr., 39, 1217-19, 1926.

Nobl used dextrose in the injection treatment of varicose veins.



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Venous Disease
  • 3004.1
  • 4897.2

Traumatic aneurysm of the intracranial portion of the internal carotid artery. With a note by Wilfred Trotter.

Brain, 51, 184-208, 1928.

In 1924 Wilfred Trotter(1872-1939) performed the first planned operation for intracranial aneurysm diagnosed pre-operatively.



Subjects: NEUROLOGY › Neurovascular Disorders, NEUROSURGERY › Vascular & Endovascular
  • 3005

The treatment of varicose veins.

Ann. Surg., 99, 799-805, 1934.

Cooper combined ligation with subsequent injection of 5 per cent sodium morrhuate in the treatment of varicose veins.



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Venous Disease
  • 3005.1

Microsurgery in anastomosis of small vessels.

Surg. Forum, 11, 243-45, 1960.

First demonstration of the value of the operating microscope in microsurgery.



Subjects: NEUROSURGERY › Vascular & Endovascular, VASCULAR SURGERY
  • 3006

Thrombose und Embolie. Gefässentzündung und septische Infektion. In his Gesammelte Abhandlungen zur wissenschaftlichen Medicin.

Frankfurt: a.M., Meidinger, Sohn u. Co., 1856.

Reprints of papers published between 1846 and 1853. Virchow gave the first clear description of thrombosis and embolism (see especially Beitr. exp. Path.,1846, 2,227-380). This work was translated into English by A. C. Matzdorff and W. R. Bell as Thrombosis and Emboli (1846-1856), Canton, MA, 1998.



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Thrombosis / Embolism
  • 3007

Beiträge zur normalen und pathologischen Anatomie der Lungen.

Dresden: G. Schönfeld’s Buchhandlung, 1862.

First description of pulmonary fat embolism in man.



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Thrombosis / Embolism, PATHOLOGY
  • 3008

Experimentelle Beiträge zur Lehre von der Embolie.

Virchows Arch. path. Anat., 25, 308-38, 433-530, 1862.

Experimental study of the effects of ligation of coronary vessels.



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Thrombosis / Embolism, CARDIOVASCULAR (Cardiac) SURGERY
  • 3009

Traité clinique et expérimental des embolies capillaires.

Paris: J.-B. Baillière, 1870.


Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Thrombosis / Embolism
  • 3010

Untersuchungen über die embolischen Processe.

Berlin: A. Hirschwald, 1872.

Cohnheim developed the doctrine of infarction as a result of occlusion of terminal arteries. He explained the haemorrhagic nature of certain infarcts on the basis of a reflux flow and diapedesis through the altered capillaries of the infarcted area.



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE, CARDIOLOGY › CARDIOVASCULAR DISEASE › Aortic Diseases, CARDIOLOGY › CARDIOVASCULAR DISEASE › Coronary Artery Disease › Myocardial Infarction
  • 3011

Thrombosis and embolism. In Allbutt, C., System of medicine, 4, 284-310; and in 2nd ed., 6, 691-821

London, 1899, 1909.


Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Thrombosis / Embolism
  • 3012

Ueber die operative Behandlung der Embolie der Lungenarterie.

Arch. klin. Chir., 86, 686-700, 1908.

Pulmonary embolectomy first attempted, “Trendelenburg’s operation” – first successfully performed by Kirschner (see No. 3016).



Subjects: CARDIOVASCULAR (Cardiac) SURGERY, PULMONOLOGY › Thoracic Surgery, VASCULAR SURGERY › Thrombosis / Embolism
  • 3013

Embolie fémorale au cours d’un rétrécissement mitral pur. Arteriotomie. Guérison.

Bull. Acad. Méd. (Paris), 3 sér., 66, 358-61, 1911.

First successful embolectomy; operation carried out by G. Labey, November 16, 1911.



Subjects: VASCULAR SURGERY › Thrombosis / Embolism
  • 3014

Ein Fall operierter Embolie der Arteria femoralis.

Wien. klin. Wschr., 26, 936-39, 1913.

Key performed his first successful embolectomy on December 4, 1912, and reported it to a meeting of the Svenska Läkaresällskapet on January 28, 1913. See also his review in Ergebn. Chir. Orthop.,1929, 22,1-94.



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Thrombosis / Embolism, VASCULAR SURGERY › Thrombosis / Embolism
  • 3014.1

Fall von Embolus aortae abdominalis, Operation, Heilung.

Zbl. Chir., 40, 1945-46, 1913.

First successful aortic embolectomy.



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Thrombosis / Embolism, CARDIOVASCULAR (Cardiac) SURGERY
  • 3015

Traumatic lipaemia and fatty embolism.

Int. Clin., 23 ser., 4, 171-227, 1913.

Classic clinical description of pulmonary fat embolism.



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Thrombosis / Embolism, VASCULAR SURGERY › Thrombosis / Embolism
  • 3016

Ein durch die Trendelenburgsche Operation geheilter Fall von Embolie der Art. pulmonalis.

Arch. klin. Chir., 133, 312-59, 1924.

First successful surgical treatment of pulmonary embolism, a procedure suggested by Trendelenburg in 1908 (see No. 3012).



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Thrombosis / Embolism, CARDIOVASCULAR (Cardiac) SURGERY, PULMONOLOGY › Thoracic Surgery
  • 3017

Report of a successful case of embolectomy.

Brit. med. J., 2, 985-87, 1925.

First successful embolectomy in Britain.



Subjects: NEUROSURGERY › Vascular & Endovascular, VASCULAR SURGERY › Thrombosis / Embolism
  • 3018

Phlébites, thromboses et embolies post-opératoires.

Paris: Masson & Cie, 1929.


Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Thrombosis / Embolism, VASCULAR SURGERY › Thrombosis / Embolism
  • 3019

Heparin and the thrombosis of veins following injury.

Surgery, 2, 163-87, 1937.

Order of authorship in the original publication: Murray, Jaques, Perrett, Best. Heparin was discovered by Jay McLean and William Henry Howell in 1916; however it was not tested as an anticoagulant in clinical trials until 1935.  With L.B. Jaques, T. S. Perrett.



Subjects: HEMATOLOGY › Anticoagulation, VASCULAR SURGERY
  • 3019.1

Sur la désobstruction des thromboses artérielles anciennes.

Mém. Acad. Chir. (Paris), 73, 409-16, 1947.

In 1946 Santos removed a thrombus and atheroma plaque from an artery in order to unblock it, and, using the knowledge acquired from Gordon Murray, placed the patient on heparin in order to avoid re-thrombosis. Called endarteriectomy, this technique spread around the world and remains the method of choice for treating severe stenoses and segmental obstructions in the arteries.



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Thrombosis / Embolism, VASCULAR SURGERY › Thrombosis / Embolism
  • 3020

Report of the Committee for the Evaluation of Anticoagulants in the Treatment of Coronary Thrombosis with Myocardial Infarction.

Amer. Heart J., 36, 801-15, 1948.

With C. D. Marple and D. F. Beck.



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Coronary Artery Disease › Myocardial Infarction, CARDIOLOGY › CARDIOVASCULAR DISEASE › Thrombosis / Embolism
  • 3020.1

La greffe vasculaire dans les thromboses du carrefour aortique.

Presse méd., 59, 234-6, 1951.

Arterial homograft on aorta.



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Thrombosis / Embolism, CARDIOVASCULAR (Cardiac) SURGERY
  • 3020.2

A method for extraction of arterial emboli and thrombi.

Surg. Gynec. Obstet., 116, 241-44, 1963.

Introduction of the balloon catheter in arterial embolectomy. With J. J. Cranley, R. J. Krause, E. S. Strasser and C. D. Hafner.



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Thrombosis / Embolism, CARDIOVASCULAR (Cardiac) SURGERY, VASCULAR SURGERY › Thrombosis / Embolism
  • 3021

Sur l’hydrothorax et l’hydropéricarde.

Bull. Fac. Méd. Paris, 4, 373-76, 18141815.

First successful pericardiocentesis. The above reference is not to his first writing on the subject, which cannot be traced. See also Dict.Sci. med.,1819, 40, 370.



Subjects: CARDIOVASCULAR (Cardiac) SURGERY
  • 3022

Ueber die Paracentese des Perikardiums.

Schriften Univ. Kiel, (1875), Diss. Nr. 2, pp. 20, 1876.

Account of first pericardiocentesis for suppurative pericarditis.



Subjects: CARDIOVASCULAR (Cardiac) SURGERY
  • 3022.1

Production artificielle d’insuffisances tricuspidienne mitrale et aortique, isolées ou combinées chez le chien.

C. R. Soc. Biol. (Paris), 7 sér., 4, 108-10, 1882.

Experimental valvulotomy. Translation in Amer. J. Cardiol.,1973, 32,993.



Subjects: CARDIOVASCULAR (Cardiac) SURGERY
  • 3022.2

Stab wound of pericardium; resection of rib; suture of pericardium; recovery.

Trans. med. Assoc. (Missouri), 218-23, 1894.

“This was the first report in America and probably world-wide in which there was a successful evacuation of a traumatic hemopericardium and a suture placed in the pericardium. Dalton’s patient was operated on in September, 1891… The patient survived his ordeal and was discharged from the hospital in three and a half months” (Rutkow).



Subjects: CARDIOVASCULAR (Cardiac) SURGERY
  • 3023

Fall von penetrirender Stichverletzung des rechten Ventrikel’s. Herznaht.

Zbl. Chir., 23, 1048-49, 1896.

Rehn was the first successfully to suture a wound of the human heart.



Subjects: CARDIOVASCULAR (Cardiac) SURGERY
  • 3023.1

Ueber penetrirende Herzwunden und Herznaht.

Arch. klin. Chir., 55, 315-29, 1897.

Before 1896 wounds of the heart had always been regarded as fatal. Rehn’s work marks the begining of cardiac surgery. English translation in Callahan, Keys & Key, Classics of Cardiology, vol. 3, 34-44.  See

See Karel B. Absolon and Mohammad Naficy, First successful cardiac operation in a human 1896: A documentation. The life, the times and the work of Ludwig Rehn (1849-1930). Rockville, MD, 2002.



Subjects: CARDIOVASCULAR (Cardiac) SURGERY
  • 3024

Chirurgie du grand sympathique et du corps thyroïde.

Lyon: A. Storck, 1900.

Jaboulay was the first to perform the operation of sympathectomy for the relief of vascular disease.



Subjects: CARDIOVASCULAR (Cardiac) SURGERY
  • 3025

Ueber chronich adhäsive Mediastino-Perikarditis und deren Behandlung.

Münch. med. Wschr., 49, 1072, 1732, 1902.

Brauer was first to suggest the operation of cardiolysis, a procedure carried out by Petersen.



Subjects: CARDIOVASCULAR (Cardiac) SURGERY
  • 3025.1

The transplantation of veins and organs.

Amer. Med., 10, 1101-2, 1905.

Reports experimental heart transplantation in a dog. See also the earlier paper on pp. 284-5.



Subjects: CARDIOVASCULAR (Cardiac) SURGERY › Heart Transplants, TRANSPLANTATION
  • 3025.2

Nuevas trabajos de cirugía vascular; substitución plástica de las arteriás por las venas, ó arterioplastia venosa, aplicada, como nuevo metodo, al tratamiento de los aneurismas.

Siglo méd., 53, 546-8, 561-4, 1906.

Goyanes used vein grafts to restore arterial flow.



Subjects: CARDIOVASCULAR (Cardiac) SURGERY, VASCULAR SURGERY
  • 3025.3

Ligation of the ductus arteriosus.

Ann. Surg., 46, 335-38, 1907.

Munro was first to suggest the feasibility of ligation of a patent ductus arteriosus.



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Arterial Disease, GENETICS / HEREDITY › HEREDITARY / CONGENITAL DISEASES OR DISORDERS › Congenital Heart Defects, VASCULAR SURGERY › Ligations
  • 3026

The surgery of blood vessels, etc.

Johns Hopk. Hosp. Bull., 18, 18-28, 1907.

Carrel’s remarkable technique of end-to-end anastomosis of blood vessels; see also No. 2909.



Subjects: CARDIOVASCULAR (Cardiac) SURGERY
  • 3027

Results of the transplantation of blood vessels, organs and limbs.

J. Amer. med. Assoc., 51, 1662-67, 1908.

Carrel showed that arteries kept for days or weeks outside the body can be transplanted successfully.



Subjects: CARDIOVASCULAR (Cardiac) SURGERY, TRANSPLANTATION
  • 3028

Latent life of arteries.

J. exp. Med., 12, 460-86, 1910.

Carrel’s experiments showed that it was possible to preserve portions of blood vessels in cold storage for long periods before using them in transplantation. For an appreciation of Carrel, see Garrison’s History, p. 733.



Subjects: CARDIOVASCULAR (Cardiac) SURGERY, TRANSPLANTATION
  • 3028.01

Experimental surgery of the aorta and heart.

Ann. Surg., 52, 83-95, 1910.

Carrel attempted the direct placement of a bypass vessel in a dog.



Subjects: CARDIOVASCULAR (Cardiac) SURGERY
  • 3028.1

Chirurgie des malformations congénitales ou acquises du coeur.

Congr. franç. Chir., Proc.-verb., 26, 1062-65; Presse méd., 21, 860, 1913.

First attempt at surgical relief of valvular disease of the heart (congenital pulmonary stenosis). Experimental valvotomy.



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Heart Valve Disease, CARDIOVASCULAR (Cardiac) SURGERY, GENETICS / HEREDITY › HEREDITARY / CONGENITAL DISEASES OR DISORDERS › Congenital Heart Defects
  • 3029

Etude expérimentelle sur la chirurgie des valvules du coeur.

Bull. Acad. Méd. (Paris), 3 sér., 71, 293-95, 1914.

Tuffier carried out the first successful experimental operation for the relief of chronic valvular disease. He also operated successfully in a case of aortic stenosis.



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Heart Valve Disease, CARDIOVASCULAR (Cardiac) SURGERY
  • 3030

Un cas de cardiolyse.

Bull. Mém. Soc. Chir. Paris., 47, 1120-21, 1921.

First pericardiectomy, for constrictive pericarditis.



Subjects: CARDIOVASCULAR (Cardiac) SURGERY
  • 3030.1

Cardiotomy and valvulotomy for mitral stenosis. Experimental observations and clinical notes concerning an operated case with recovery.

Boston med. surg. J., 188, 1023-27, 1923.

Successful section of mitral valve for relief of mitral stenosis.



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Heart Valve Disease, CARDIOVASCULAR (Cardiac) SURGERY
  • 3031

Ueber Erkennung und Behandlung der Umklammerung des Herzens durch schwielige Perikarditis.

Klin. Wschr., 2, 5-9, 1923.

First complete pericardiectomy for constrictive pericarditis.



Subjects: CARDIOVASCULAR (Cardiac) SURGERY
  • 3032

The surgical treatment of mitral stenosis.

Brit. med. J., 2, 603-06, 1925.

Mitral valvotomy; report of a successful case.



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Heart Valve Disease, CARDIOVASCULAR (Cardiac) SURGERY
  • 2899
  • 3033

Congestive heart failure and angina pectoris: The therapeutic effect of thyroidectomy on patients without clinical or pathologic evidence of thyroid toxicity.

Arch. intern. Med., 51, 866-77, 1933.

Thyroidectomy for congestive heart failure and angina pectoris. With D. D. Berlin.



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Coronary Artery Disease › Angina Pectoris, ENDOCRINOLOGY › Thyroid
  • 3034

The development of a new blood supply to the heart by operation.

Ann. Surg., 102, 801-13, 1935.

By implantation of the pectoral muscle into the pericardium, Beck provided a collateral circulation to the heart for the relief of myocardial ischemia. This paper recorded the first operation on a man. It was preceded by Beck’s paper, written with V.L. Tichy an A.R. Moritz, recording operations on dogs: "Production of a collateral circulation to the heart", Proc. Soc. exp. Biol. Med.,1935, 32,759-61.



Subjects: CARDIOVASCULAR (Cardiac) SURGERY
  • 3035

The production of a collateral circulation to the heart. I. An experimental study.

Amer. Heart J., 10, 849-73, 1935.


Subjects: CARDIOVASCULAR (Cardiac) SURGERY
  • 3036

The surgical treatment of hypertension.

Proc. Calif. Acad. Med., 5, 58-90, 19351936.

Peet operation for hypertension. Preliminary communication in Univ. Hosp. Bull. (Ann Arbor), 1935, 1,17-18.



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Hypertension (High Blood Pressure), SURGERY: General
  • 3037

An experimental method of providing a collateral circulation to the heart.

Brit. J. Surg., 23, 665-70, 1936.

By attaching a pedicled omental graft to the surface of the heart (cardio-omentopexy), thus providing a collateral circulation to that organ, O’Shaughnessy made an important advance in the treatment of angina and cardiac ischemia generally.



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Coronary Artery Disease › Angina Pectoris, CARDIOVASCULAR (Cardiac) SURGERY
  • 3038

Arterectomy.

Surg. Gynec. Obstet., 64, 149-55, 1937.

Arterectomy in arterial thrombosis. With R. Fontaine and S. M. Dupertuis.



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Arterial Disease, CARDIOVASCULAR (Cardiac) SURGERY
  • 3038.1

An oxygenator with a large surface–volume ratio.

J. Lab. clin. Med., 24, 1192-98, 1939.

First heart–lung machine used successfully on an animal.



Subjects: CARDIOVASCULAR (Cardiac) SURGERY, INSTRUMENTS & TECHNOLOGIES › Medical Instruments › Heart-Lung Machine
  • 3039

Surgical ligation of a patent ductus arteriosus: Report of first successful case.

J. Amer. Med. Surg., 112, 729-31, 1939.

One of the earliest successful surgical repairs for congenital heart disease. See also later paper in Ann. Surg.,1939, 110, 321-56.



Subjects: CARDIOVASCULAR (Cardiac) SURGERY, GENETICS / HEREDITY › HEREDITARY / CONGENITAL DISEASES OR DISORDERS › Congenital Heart Defects, Pediatric Surgery
  • 3040

De la résection du carrefour aortico-iliaque avec double sympathectomie lombaire pour thrombose artéritique de l’aorte; le syndrome de l’oblitération termino-aortique par artérite.

Presse méd., 48, 601-04, 1940.

Obliteration of the abdominal aorta.



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Arterial Disease, CARDIOVASCULAR (Cardiac) SURGERY
  • 3041

A technique for splanchnic resection for hypertension; preliminary report.

Surgery, 7, 1-8, 1940.

Smithwick operation for hypertension.



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Hypertension (High Blood Pressure), CARDIOVASCULAR (Cardiac) SURGERY
  • 3042

Surgery of the heart.

London: E. Arnold & Co., 1941.

Includes valuable information regarding the history of the subject.



Subjects: CARDIOVASCULAR (Cardiac) SURGERY, CARDIOVASCULAR (Cardiac) SURGERY › History of Cardiac Surgery
  • 3043

The surgical treatment of malformations of the heart in which there is pulmonary stenosis or pulmonary atresia.

J. Amer. med. Assoc., 128, 189-202, 1945.

The “Blalock-Taussig operation” for the relief of congenital defects of the pulmonary artery, Tetralogy of Fallot ("blue baby syndrome").

"The first surgical repair was carried out in 1944 at Johns Hopkins.[70] The procedure was conducted by surgeon Alfred Blalock and cardiologist Helen B. Taussig, with Vivien Thomas also providing substantial contributions and listed as an assistant.[3] This first surgery was depicted in the film Something the Lord Made.[59] It was actually Helen Taussig who convinced Alfred Blalock that the shunt was going to work. 15-month-old Eileen Saxon was the first person to receive a Blalock-Thomas-Taussig shunt.[59]" (Wikipedia article on Tetralogy of Fallot).



Subjects: CARDIOVASCULAR (Cardiac) SURGERY, GENETICS / HEREDITY › HEREDITARY / CONGENITAL DISEASES OR DISORDERS › Congenital Heart Defects, Pediatric Surgery, WOMEN, Publications by › Years 1900 - 1999
  • 3044

Congenital coarctation of the aorta and its surgical treatment.

J. thorac. Surg., 14, 347-61, 1945.

Crafoord and Gross (No. 3044.1) pioneered this basic operation in cardiac and pediatric surgery.



Subjects: CARDIOLOGY › Congenital Heart Defects, CARDIOVASCULAR (Cardiac) SURGERY
  • 3044.1

Surgical correction for coarctation of the aorta.

Surgery, 18, 673-8, 1945.

Resection of coarctation and direct anastomosis of remaining ends. See also his report of 60 cases in J. Amer.med.Assoc.,1949, 139,285-92.



Subjects: CARDIOVASCULAR (Cardiac) SURGERY, GENETICS / HEREDITY › HEREDITARY / CONGENITAL DISEASES OR DISORDERS › Congenital Heart Defects
  • 3045

Anastomosis of the aorta to a pulmonary artery. Certain types in congenital heart disease.

J. Amer. med. Ass., 132, 627-31, 1946.

With S. Smith and S. Gibson.



Subjects: CARDIOVASCULAR (Cardiac) SURGERY, GENETICS / HEREDITY › HEREDITARY / CONGENITAL DISEASES OR DISORDERS › Congenital Heart Defects
  • 3046

Pulmonary valvulotomy for the relief of congenital pulmonary stenosis. Report of three cases.

Brit. med. J., 1, 1121-26, 1948.

"Brock performed the first successful valvotomies for isolated pulmonary stenosis in 1948. He gained access to the blood-filled beating heart through a small incision in the right ventricle through which he passed a valvulotome that was used to enlarge the opening of the stenotic value" (W. Bruce Fye). See Brock's book, The anatomy of congenital pulmonary stenosis, London, 1957.



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Heart Valve Disease, CARDIOVASCULAR (Cardiac) SURGERY, GENETICS / HEREDITY › HEREDITARY / CONGENITAL DISEASES OR DISORDERS › Congenital Heart Defects
  • 3046.1

The surgical treatment of mitral stenosis. 1. Valvuloplasty.

New Engl. J. Med., 239, 801-09, 1948.

Valvuloplasty for mitral stenosis. Harken reported the first successful intracardiac operation for treatment of this lesion--a procedure was first attempted in the 1920s. Charles Bailey in Philadelphia undertook a similar approach at the same time, and according to Lawrence Cohn "These surgeons began the 'modern' era of cardiac surgery." (L. H. Cohn, "Surgical Treatment of Valvular Heart Disease," Am. J. Surg. 135, 444-451, 1978). With L. B. Ellis, P. F. Ware. 



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Heart Valve Disease, CARDIOVASCULAR (Cardiac) SURGERY, WOMEN, Publications by › Years 1900 - 1999
  • 3046.2

Surgery of pulmonary stenosis. A case in which the pulmonary valve was successfully divided.

Lancet, 1, 988-9, 1948.

Operation Dec. 4, 1947.



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Heart Valve Disease, CARDIOVASCULAR (Cardiac) SURGERY
  • 3047

A venous shunt for marked mitral stenosis.

Amer. Practit., 2, 756-61, 1948.

First pulmonary-azygos shunt operation for relief of mitral stenosis. Two further patients were operated upon later the same year; all three are reported in J. AmermedAss.,1949, 140, 1259. A similar procedure was successfully employed independently by F. d’Allaines and his colleagues in 1949 (Mém. Acad. Chir., Paris, 1949, 75, 318-19).



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Heart Valve Disease, CARDIOVASCULAR (Cardiac) SURGERY
  • 3047.1

Hypothermia: its possible role in cardiac surgery: an investigation of factors governing survival in dogs at low body temperatures.

Ann. surg., 132, 849-66, 1950.

Bigelow pioneered surface-induced whole body hypothermia and temporary cardiac flow occlusion. With W.F. Greenwood.



Subjects: CARDIOVASCULAR (Cardiac) SURGERY
  • 3047.10

The use of intracardiac pacemaker in the correction of total heart block.

Surg. Forum., 9, 245-48, 1959.

First use of pacemaker for Stokes–Adams syndrome, using dogs as subjects. External power source. See also Furman and Scawadel, John B., "An intracardiac pacemaker for Stokes–Adams seizures ," New Engl. J. Med.,1959, 261, 943-48.

The addenda to the Furman and Robinson paper reports, p. 248, the first use of a transvenous lead in two patients: " Since submission of this paper for publication 2 patients with total A-V dissociation have been maintained with the use of the intracardiac pacemaker. One during an operative procedure, the second, a patient with recurrent Stokes-Adams attacks, for the past 10 weeks with the cather remaining in the heart for this entire  period of time" (Quoted by W. Bruce Fye).



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Arrythmias, CARDIOLOGY › CARDIOVASCULAR DISEASE › Arrythmias › Pacemakers, INSTRUMENTS & TECHNOLOGIES › Medical Instruments › Pacemakers
  • 3047.11

The treatment of complete heart block by the combined use of a myocardial electrode and artificial pacemaker.

Surg. Forum, 8, 360-63, 1958.

Order of authorship in the original publication: Weirich, Gott, Lillehei. Attachment of a wire to the ventricular epicardium, and bringing it out percutaneously to an external pacemaker. This was a key development leading to the pacemaker industry.



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Arrythmias, CARDIOLOGY › CARDIOVASCULAR DISEASE › Arrythmias › Pacemakers, INSTRUMENTS & TECHNOLOGIES › Medical Instruments › Pacemakers
  • 3047.12

Clinical use of an elastic Dacron prosthesis.

Arch. Surg., 77, 538-51, 1958.

Arterial prosthesis. With L. C. France, R. F. Smith, and J. G. Whitcomb.



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Arterial Disease, CARDIOVASCULAR (Cardiac) SURGERY, CARDIOVASCULAR (Cardiac) SURGERY › Cardiothoracic Prostheses
  • 3047.13

Ventricular aneurysm following myocardial infarction: Results of surgical treatment.

Ann. Surg., 150, 595-612, 1959.

Cardiopulmonary bypass and open excision of the aneurysm. With W.S. Henly, K.H. Amad, & D.W. Chapman.



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Coronary Artery Disease › Myocardial Infarction, CARDIOVASCULAR (Cardiac) SURGERY
  • 3047.14

Studies on orthotopic homotransplantation of the canine heart.

Surg. Forum., 11, 18-19, 1960.

Important experimental technique (Shumway); reported eight heart homotransplants.



Subjects: CARDIOVASCULAR (Cardiac) SURGERY, CARDIOVASCULAR (Cardiac) SURGERY › Heart Transplants, TRANSPLANTATION
  • 3047.15

A transistorized, self-contained, implantable pacemaker for the long-term correction of complete heart block.

Surgery, 48, 643-54, 1960.

The first fully-implantable pacemaker. 



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Arrythmias, CARDIOLOGY › CARDIOVASCULAR DISEASE › Arrythmias › Pacemakers, INSTRUMENTS & TECHNOLOGIES › Medical Instruments › Pacemakers
  • 3047.16

Mitral replacement: The shielded ball valve prothesis.

J. thorac. cardiovasc. Surg., 42, 673-82, 1961.

On September 21, 1960, Starr successfully inserted a “ball-in-cage” prosthetic valve (the Starr-Edwards heart valve) into a patient’s mitral valve, which was severely diseased as a result of rheumatic fever. This was the first replacement of the mitral valve in a human. See also Starr & Edwards, "Mitral replacement: Clinical experience with a ball-valve prosthesis," Annals of Surgery, 154 (1961) 726-740.

See A. N. Matthews, "The development of the Starr-Edwards heart valve," Tex .Heart Inst J. , 25 (1998) 282–293.



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Heart Valve Disease, CARDIOVASCULAR (Cardiac) SURGERY, CARDIOVASCULAR (Cardiac) SURGERY › Cardiothoracic Prostheses
  • 3047.17

Homograft replacement of the aortic valve.

Lancet, 2, 487 (only), 1962.

Homograft valve placed below coronary orifice, a single page report. The first complete report on the "Ross procedure" was "Homotransplantation of the aortic valve in the subcoronary posittion,"  J. thorac. cardiovasc. Surg. 47 (1964) 713-19.



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Heart Valve Disease, CARDIOVASCULAR (Cardiac) SURGERY
  • 3047.18

Homograft aortic valve replacement in aortic incompetence and stenosis.

Thorax, 19, 131-50, 1964.

Subcoronary homograft valve; report on 44 patients, of whom 41 survived. Barratt-Boyes was a pioneering cardiac surgeon in New Zealand.



Subjects: CARDIOVASCULAR (Cardiac) SURGERY, COUNTRIES, CONTINENTS AND REGIONS › New Zealand
  • 3047.19

Heart transplantation in man: Developmental studies and report of a case.

J. Amer. med. Assoc., 188, 1132-40, 1964.

Heart transplant from a chimpanzee into a man; unsuccessful. Hardy was expecting the donor heart to be obtained from a relatively young patient dying of brain damage, but the patient went into terminal myocardial failure before a human organ could be obtained. The recipient was a prisoner serving a life sentence for murder; he died 18 days after the operation. Westaby and Bosher, Landmarks in cardiac surgery (Oxford, 1999) 259-260.

The paper has seven co-authors.



Subjects: CARDIOVASCULAR (Cardiac) SURGERY › Heart Transplants, TRANSPLANTATION
  • 3047.2

Aortic plastic valvular prosthesis.

Bull. Georgetown Univ. Med. Center, 4, 128-30, 1951.

Hufnagel designed and inserted the first workable prosthetic heart valve in man.



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Heart Valve Disease, CARDIOVASCULAR (Cardiac) SURGERY, CARDIOVASCULAR (Cardiac) SURGERY › Cardiothoracic Prostheses
  • 3047.20

A human cardiac transplant: An interim report of a successful operation performed at Groote Schuur Hospital, Cape Town.

S. Afr. med. J., 41, 1271-4, 1967.

First human heart transplant. The operation was on Dec. 3, 1967, and the patient died on Dec. 21.



Subjects: CARDIOVASCULAR (Cardiac) SURGERY › Heart Transplants, COUNTRIES, CONTINENTS AND REGIONS › South Africa, TRANSPLANTATION
  • 3047.21

Saphenous vein autograft replacement of severe segmental coronary artery occlusion: Operative technique.

Ann. Thorac. Surg., 5, 334-39, 1968.

First report on bypass of a human coronary artery. See No. 3047.25. Two years later Favoloro published a monograph on the topic: Surgical treatment of coronary arteriosclerosis (Baltimore, 1970). Digital facsimile from annalsthoracicsurgery.org at this link.



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Coronary Artery Disease, CARDIOVASCULAR (Cardiac) SURGERY
  • 3047.22

A new approach to “anatomic” repair of transposition of the great arteries.

Mayo Clinic Proc., 41, 1-12, 1969.

The Rastelli procedure. “Intraventricular rerouting of left ventricular output through the ventricular septal defect to the aorta and establishing of a new right ventricular outflow through the ventriculotomy and an extracardiac conduit to the pulmonary artery” (Callahan, McGoon, & Key, Classics of Cardiology).



Subjects: CARDIOVASCULAR (Cardiac) SURGERY › Congenital Heart Defects, Pediatric Surgery
  • 3047.23

Surgical treatment of Wolff–Parkinson–White syndrome.

Ann. thorac. surg., 8, 1-11, 1969.

Surgical management of the tachycardia of Wolff–Parkinson–White syndrome.



Subjects: CARDIOVASCULAR (Cardiac) SURGERY
  • 3047.24

Surgical repair of triscuspid atresia.

Thorax, 26, 240-48, 1971.

Fontan procedure. “Anastomosis between the divided superior vena cava and the right pulmonary artery, anastomosis of the right atrium to the pulmonary artery, and insertion of a homograft valve in the ostium of the inferior vena cava” (Callahan, McGoon & Key, Classics of Cardiology).



Subjects: CARDIOVASCULAR (Cardiac) SURGERY
  • 3047.25

Aortocoronary bypass with saphenous vein graft: seven year follow-up.

J. Amer. med. assoc., 223, 792-94, 1973.

"Probably the first successful saphenous bypass graft was by Edward Garrett (1964), whilst he was working with DeBakey. He performed the bypass graft in order to wean a patient from cardiopulmonary bypass, and the long-term result of the procedure was not reported until 10 years later [this article]." (Westaby and Bosher, 196). See No. 3047.21



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Aortic Diseases, CARDIOVASCULAR (Cardiac) SURGERY
  • 3047.3

The use of tubes constructed from Vinyon “N” cloth in bridging arterial defects.

Ann. Surg., 135, 332-6, 1952.

Introduction of plastic material to repair arterial defects. Voorhees later abandoned this material in favour of Dacron. With A. Jaretzki and A. W. Blakemore.



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Arterial Disease, CARDIOVASCULAR (Cardiac) SURGERY, CARDIOVASCULAR (Cardiac) SURGERY › Cardiothoracic Prostheses
  • 3047.4

Successful resection of aneurysm of thoracic aorta and replacement by graft.

J. amer. med. Assoc., 152, 673-76, 1953.


Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Aortic Diseases, CARDIOVASCULAR (Cardiac) SURGERY
  • 3047.5

Application of a mechanical heart and lung apparatus to cardiac surgery.

Minn. Med., 37, 171-80, 185, 1954.

First pump oxygenator used on humans. Performed on May 6, 1953, this was the first successful intracardiac operation in a patient with the use of total heart-lung bypass.



Subjects: CARDIOVASCULAR (Cardiac) SURGERY, INSTRUMENTS & TECHNOLOGIES › Medical Instruments › Heart-Lung Machine
  • 3047.6

Controlled cross circulation for open intracardiac surgery; physiologic studies and results of creation and closure of ventricular septal defects.

J. Thorac. Surg., 28, 331-43, 1954.

Warden and colleagues undertook the first repair of various cardiac anomalies. With M. Cohen, and R.C. Read.



Subjects: CARDIOVASCULAR (Cardiac) SURGERY, GENETICS / HEREDITY › HEREDITARY / CONGENITAL DISEASES OR DISORDERS › Congenital Heart Defects
  • 3047.7

Controlled cross circulation for direct-vision intracardiac surgery; correction of ventricular septal defects, atrioventricularis communis, and tetralogy of Fallot.

Postgrad. Med., 17, 388-96, 1955.

Controlled cross circulation (human heart–lung “machine”) for intracardiac surgery.



Subjects: CARDIOLOGY › Congenital Heart Defects, CARDIOVASCULAR (Cardiac) SURGERY, INSTRUMENTS & TECHNOLOGIES › Medical Instruments › Heart-Lung Machine
  • 3047.8

Homologous aortic-valve-segment transplants as surgical treatment for aortic and mitral insufficiency.

Angiology, 7, 466-71, 1956.

First successful aortic valve homograft. For report of six-year follow-up, see A. J. Kerwin, et al., New Engl. J. Med.,1962, 266,852.



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Aortic Diseases, CARDIOVASCULAR (Cardiac) SURGERY, TRANSPLANTATION
  • 3047.9

A simple, expendable, artificial oxygenator for open heart surgery.

Surg. Clin. North America, 36, 1025-34, 1956.

DeWall bubble oxygenator. With six co-authors.



Subjects: CARDIOVASCULAR (Cardiac) SURGERY, INSTRUMENTS & TECHNOLOGIES
  • 3048

Liber theoricae nec non practicae Alsaharavii.

Augsburg: imp. S. Grimm & M. Vuirsung, 1519.

This is the first printing of the medical and therapeutic section of Abul Qasim’s medical encyclopedia or al-Tasrif. It contains what is probably the earliest description of hemophilia (fol. 145). Digital facsimile from Google Books at this link.



Subjects: Encyclopedias, GENETICS / HEREDITY › HEREDITARY / CONGENITAL DISEASES OR DISORDERS › Blood Disorders, GENETICS / HEREDITY › HEREDITARY / CONGENITAL DISEASES OR DISORDERS › Blood Disorders › Hemophilia, HEMATOLOGY, MEDIEVAL MEDICINE , MEDIEVAL MEDICINE › Medieval Islamic or Arab Medicine
  • 3049

Curationum medicinalium centuriae quatuor.

Basel: H. Frobenius, 1556.

Contains (Cent. iii, curat. 70, p. 286) first recorded case of purpura as a separate entity, not associated with fever. English translation of this section in Major, Classic descriptions of disease, 3rd. ed., 1945, p. 514.



Subjects: HEMATOLOGY › Blood Disorders, Jews and Medicine
  • 3050

Iatrologismorum seu medicinalium observationum pentecostae quinque utilibus praeceptis.

Rome: F. Moneta, 1652.

Panaroli described hemolytic jaundice of the newborn.



Subjects: GENETICS / HEREDITY › HEREDITARY / CONGENITAL DISEASES OR DISORDERS › Icterus Gravis Neonatorum, HEMATOLOGY › Blood Disorders, PEDIATRICS › Neonatology
  • 3051

Epistolica dissertatio altera pro spicilegio observationum de morbo maculoso haemorrhagico et noxiis nonnulis mytulis perscripta.

Braunschweig, 1735.

Behrens gave the name “morbus maculosus haemorrhagicus” to the disease purpura haemorrhagica. His paper is reprinted in Werlhof’s Opera medica, Hannover, 1775, 2,615-36.



Subjects: HEMATOLOGY › Blood Disorders
  • 3052

Disquisitio medica et philologica de variolis et anthracibus.

Hannover: sumt. haered. Nicolai Foersteri, 1735.

Werlhof gave a classic description of purpura haemorrhagica (“Werlhof’s disease”).



Subjects: HEMATOLOGY › Blood Disorders
  • 2207
  • 3053
  • 4491

Commentarii de morborum historia et curatione.

London: T. Payne, 1802.

Samuel Johnson called Heberden “the last of our learned physicians”. The above work included all his important papers, which had earned him his great reputation, and which are dealt with elsewhere in this database (see Nos. 2887, 2291, 5438, 5831). Heberden's book was published posthumously by Heberden’s son, and at once acquired a European reputation; “it had the distinction of being the last important medical treatise written in Latin” (Rolleston). An English translation also appeared in 1802. Chap. 78 reports two cases of anaphylactoid (abdominal) purpura. Henoch (No. 3065) and Schönlein (No. 3058) established this condition as a distinct entity. In his chapter De nodis digitorum Heberden described a form of rheumatic gout in which nodules (“Heberden’s nodes”) appeared at the interphalangeal joints of the fingers. Heberden's introduction to the book, written in 1767, was not published until the 4th edition (1816).



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Coronary Artery Disease › Angina Pectoris, HEMATOLOGY › Blood Disorders, Medicine: General Works, RHEUMATOLOGY › Gout (Podagra)
  • 3054

An account of an haemorrhagic disposition existing in certain families.

Med. Reposit., 6, 1-4, 1803.

Otto recognized and adequately described hemophilia, noting that females are not affected but may transmit the disease. His paper is one of the first great contributions to medicine in North America. Reproduced in Major, Classic descriptions of disease, 3rd ed., 1945, p. 522.



Subjects: GENETICS / HEREDITY › HEREDITARY / CONGENITAL DISEASES OR DISORDERS › Blood Disorders › Hemophilia, HEMATOLOGY › Blood Disorders
  • 3055
  • 405

Observations on the surgical anatomy of the head and neck.

Edinburgh: T. Bryce, 1811.

Burns was the first to suggest (p. 31) ligature of the innominate artery. His book describes “Burns’s space”, the fascial space at the suprasternal notch.

The first recorded case of chloroma (myeloid sarcoma, granulocytic sarcoma, extramedullary myeloid tumor), a manifestation of acute myeloid leukemia, is found on p. 396 of this book. This was of course, about 30 years before leukemia was understood as a disease.



Subjects: ANATOMY › 19th Century, HEMATOLOGY › Blood Disorders, ONCOLOGY & CANCER › Leukemia, VASCULAR SURGERY
  • 3056

Von einer erblichen Neigung zu tödtlichen Blutungen.

Arch. med. Erfahr., 1, 385-434., 1820.

In his description of hemophilia Nasse stressed the immunity of females, despite their ability to transmit the disease. This fact has become known as “Nasse’s law”.



Subjects: HEMATOLOGY › Blood Disorders
  • 3057

Observations sur l’état des veines dans les infiltrations des membres.

J. Physiol. exp. path, 3, 89-93., 1823.

Description of venous obstruction and edema.



Subjects: CARDIOLOGY › CARDIOVASCULAR DISEASE › Venous Disease
  • 3058

Peliosis rheumatica. In his Allgemeine und specielle Pathologie und Therapie, 2, 48-49.

1837.

“Schönlein’s disease” (purpura) first described. English translation in No. 2241.



Subjects: HEMATOLOGY › Blood Disorders
  • 3058.1

Successful transfusion of blood.

Lancet, 1, 185-88, 18401841.

Blood transfusion used in treatment of hemophilia.



Subjects: HEMATOLOGY › Blood Disorders, THERAPEUTICS › Blood Transfusion
  • 3059

Experimental and practical researches on inflammation and on the origin and nature of tubercles of the lungs.

London: John Churchill, 1843.

Addison made important observations on the blood corpuscles. He is by some considered “the world’s first hematologist”. He gave the first description of leucocytosis, so named by Virchow in 1858, and he anticipated Cohnheim’s conception of inflammation. He was first to observe diapedesis. See Lancet, 1907, 1,182-83. See also No. 2294.



Subjects: HEMATOLOGY, HEMATOLOGY › Blood Disorders
  • 3060

Essai d’hématologie pathologique.

Paris: Fortin, Masson & Cie, 1843.

The first monograph on hematology in its "modern" sense. Andral established analysis of the blood on the basis of exact knowledge of the blood components. He analysed the blood fibrin and albumin. He recognized several forms of anemia, including that due to lead poisoning. English translation, 1844.



Subjects: HEMATOLOGY, OCCUPATIONAL HEALTH & MEDICINE , TOXICOLOGY › Lead Poisoning
  • 267.1
  • 3060.1

Cours de microscopie. 1 vol. and atlas.

Paris: J.-B. Baillière, 18441845.

Donne's and Foucault's work was the first biomedical textbook to be illustrated with images made from photomicrographs, in this case daguerreotypes of blood cells. Among its noteworthy images are the first microphotographs of human blood cells and platelets, and the first photographic illustration of Trichomonas vaginalis, the protozoon responsible for vaginal infections, which Donné had discovered in 1836. The text volume of the Cours contains the first description of the microscopic appearance of leukemia, which Donné had observed in blood taken from both an autopsy and a living patient. His observations mark the first time that leukemia was linked with abnormal blood pathology. Foucault, who later achieved fame as a physicist, initally studied medicine, which he abandoned for physics due to an extreme fear of blood. Foucault initially directed his attention to the improvement of Louis Daguerre's photographic processes. For three years he was experimental assistant to Donné in his course of lectures on microscopy.

 



Subjects: HEMATOLOGY, HEMATOLOGY › Blood Disorders, IMAGING › Photography / Photomicrography , MICROBIOLOGY, Microscopy, OBSTETRICS & GYNECOLOGY › GYNECOLOGY, ONCOLOGY & CANCER › Leukemia
  • 3061

Case of hypertrophy of the spleen and liver, in which death took place from suppuration of the blood.

Edinb. med. surg. J., 64, 413-23, 1845.

First definite description of leukemia as a blood disorder; a case under the care of Sir R. Christison but reported by Bennett. On p. 400 of the same journal is a report of a case by D. Craigie, referring to a patient seen in 1841 but not recognized as leukemia until Craigie heard of Bennett’s case in the same hospital. Bennett published a monograph on leucocythemia in 1852, in which he included the first illustrations of the microscopic appearance of the blood in leukemia.



Subjects: HEMATOLOGY › Blood Disorders, ONCOLOGY & CANCER › Leukemia
  • 3062

Weisses Blut.

N. Notiz. Geb. Natur- u. Heilk, 36, 151-56., 1845.

Only six weeks after Bennett, Virchow independently published a report on the necropsy of a case of leukemia. He gave the condition its present name. For translation, see Major, Classic descriptions of disease, 3rd. ed., 1945, p. 510.



Subjects: HEMATOLOGY › Blood Disorders, ONCOLOGY & CANCER › Leukemia
  • 3062.1

Particulars of a case in which enormous enlargement of the spleen and liver, together with dilatation of all the blood vessels of the body, were found coincident with a peculiarly altered condition of the blood.

Lancet, 2, 43-44, 1846.

Leukemia diagnosed during life as the result of a blood examination.



Subjects: HEMATOLOGY › Blood Disorders, ONCOLOGY & CANCER › Leukemia
  • 3063

Die Haemophilie oder die Bluterkrankheit.

Leipzig: O. Wigand, 1855.

First full clinical description of hemophilia.



Subjects: GENETICS / HEREDITY › HEREDITARY / CONGENITAL DISEASES OR DISORDERS › Blood Disorders › Hemophilia, HEMATOLOGY › Blood Disorders
  • 3064

Ueber farblose Blutkörperchen und Leukämie. In his Gesammelte Abhandlungen zur wissenschaftlichen Medicin, pp. 147-218.

Frankfurt: Meidinger, 1856.

Includes his paper on “weisses Blut” (see No. 3062) and three later papers on leukemia. See No. 3006.



Subjects: HEMATOLOGY › Blood Disorders, ONCOLOGY & CANCER › Leukemia
  • 3064.1

Ein neuer Fall von Leukämie.

Virchows Arch. path. Anat., 12, 37-58., 1857.

Acute leukemia first described.



Subjects: HEMATOLOGY › Blood Disorders, ONCOLOGY & CANCER › Leukemia
  • 3064.2

Hereditary epistaxis.

Lancet, 2, 362-63, London, 1865.


Subjects: GENETICS / HEREDITY › GENETIC DISORDERS › Osler-Weber-Rendu Disease, HEMATOLOGY › Blood Disorders
  • 3065

Über den Zusammenhang von Purpura und Intestinalstörungen.

Berl. klin. Wschr., 5, 517-19, 1868.

“Henoch’s purpura”. Henoch described a form of purpura with abdominal symptoms first mentioned by Heberden (No. 3053). See also the same journal, 1874, 11,622, 641-43. This paper is translated into English in No. 2241.



Subjects: HEMATOLOGY › Blood Disorders
  • 3066

Ein Fall von Leukämie mit Erkrankung des Knochenmarkes.

Arch. Heilk. (Lpz.), 11, 1-14, 1870.

Neumann was the first to note changes in the bone marrow in leukemia, and he proposed the term “myelogenous leukemia”.



Subjects: HEMATOLOGY › Blood Disorders, ONCOLOGY & CANCER › Leukemia
  • 3067

Ueber das Vorkommen von Bilirubinkrystallen bei neugebornen Kindern.

Virchows Arch. path. Anat., 63, 447-62, 1875.

Kernicterus first described.



Subjects: HEMATOLOGY › Blood Disorders, PEDIATRICS › Neonatology
  • 3067.1

A case of haemophilia: pedigree through five generations.

Lancet, 2, 533-34, 1886.

True hemophilia in a female. The family was the subject of several later investigations, the last being reported in Lancet, 1973, 2,734.



Subjects: GENETICS / HEREDITY › HEREDITARY / CONGENITAL DISEASES OR DISORDERS › Blood Disorders › Hemophilia, HEMATOLOGY › Blood Disorders
  • 3068

Ueber Purpura fulminans.

Berl. klin. Wschr., 24, 8-10, 1887.

First description.



Subjects: HEMATOLOGY › Blood Disorders
  • 3069

Die Gelenkerkrankungen bei Blutern mit Berücksichtigung der Diagnose.

Samml. klin. Vortr., Chir., N.F., Nr. 11, 233-42, 1890.

König gave a detailed description of joint involvement in hemophilia.



Subjects: GENETICS / HEREDITY › HEREDITARY / CONGENITAL DISEASES OR DISORDERS › Blood Disorders › Hemophilia, HEMATOLOGY › Blood Disorders
  • 3069.1
  • 887

Farbenanalytische Untersuchungen zur Histologie und Klinik des Blutes.

Berlin: A. Hirschwald, 1891.

Extension of Ehrlich’s work on the differential blood count. By means of his methods of staining blood cells Ehrlich differentiated two types of leukemia, lymphatic and myelogenous.

 

 

 



Subjects: HEMATOLOGY, HEMATOLOGY › Blood Disorders, ONCOLOGY & CANCER › Leukemia
  • 3070

Sur une forme spéciale de cyanose s’accompagnant d’hyperglobulie excessive et persistante.

C. R. Soc. Biol. (Paris), 44, 384-88, 1892.

Vaquez first described polycythemia vera (erythremia). Osler’s paper on the subject (No. 3073) made it generally known in the English-speaking world, and the condition has since been named “Vaquez–Osler disease”. For translation, see Major, Classic descriptions of disease, 3rd ed., 1945, p. 497.



Subjects: HEMATOLOGY › Blood Disorders
  • 3071

A new preparation for rapidly fixing and staining blood.

Lancet, 1, 370-71, 1899.

Jenner’s methylene blue-eosin stain for blood.



Subjects: HEMATOLOGY
  • 3072

A fatal case of acute primary infectious pharyngitis.

Trans. Med. Soc. Calif., 93-101, 1901.

First recorded case of extreme leucopenia.



Subjects: HEMATOLOGY › Blood Disorders, U.S.: CONTENT OF PUBLICATIONS BY STATE & TERRITORY › California
  • 3073

Chronic cyanosis, with polycythaemia and enlarged spleen: a new clinical entity.

Amer. J. med. Sci., 126, 187-201, 1903.

When describing polycythemia with cyanosis, Osler thought it a new entity, but later acknowledged the priority of Vaquez’s description (No. 3070). Reprinted in Med. Classics, 1939, 4,254-75.



Subjects: HEMATOLOGY › Blood Disorders
  • 3074

Ueber eine Methode zur Untersuchung des lebenden Knochenmarks von Thieren und über das Bewegungsvermögen der Myelocyten.

Dtsch. med. Wschr., 29, 165-67, 1903.

Wolff-Eisner trephined the tibia and femur of experimental animals and suggested biopsy of bone marrow as a clinical procedure.



Subjects: HEMATOLOGY › Blood Disorders
  • 3075

Die neutrophilen weissen Blutkörperchen bei Infektions-Krankheiten.

Jena: Gustav Fischer, 1904.

“Arneth count”. Arneth distinguished five groups of polymorphonuclear leucocytes and advocated the estimation of these groups as a valuable aid in the determination of bone-marrow reaction to infective and other agents (plate 8, p. 37).



Subjects: HEMATOLOGY
  • 3076

Die Bedeutung der Blutdruckmessung für die Praxis.

Dtsch. Arch. klin. Med., 83, 363-409, 1905.

Includes (p. 396) description of “Geisböck’s disease” – polycythemia hypertonica.



Subjects: HEMATOLOGY › Blood Disorders
  • 3077

Pathologie der Primärerkrankungen des lymphatischen und hämatopoetischen Apparates.

Wiesbaden: J. F. Bergmann, 1905.

Includes (p. 151) Sternberg’s description of lymphogranulomatosis, which was given the eponym “Sternberg’s disease”.



Subjects: HEMATOLOGY › Blood Disorders
  • 3078

Blutkrankheiten und Blutdiagnostik.

Leipzig: Veit & Co., 19071908.


Subjects: HEMATOLOGY
  • 3079

Septische Erkrankungen bei Verkümmerung des Granulozytensystems.

Wien. klin. Wschr., 20, 157-62, 1907.

First reported case of complete agranulocytosis.



Subjects: HEMATOLOGY › Blood Disorders
  • 3079.1

Experimentelle Leukämie bei Hühnern.

Zbl. Bakt., Abt. I. Orig., 46, 595-609, 1908.

Cell-free transmission of fowl leukemia. Ellermann and Bang produced leukemia by means of a filterable agent.



Subjects: HEMATOLOGY › Blood Disorders, ONCOLOGY & CANCER › Leukemia
  • 3080

Per la patogenesi e per la diagnosi delle malattie del sangue e degli organi emopoietici. Puntura esplorativa del midollo osseo.

Clin. med. ital., 47, 724-36, 1908.

Introduction of bone marrow biopsy by puncturing the shaft of the tibia.



Subjects: HEMATOLOGY › Blood Disorders, ONCOLOGY & CANCER
  • 3080.1

Ueber den habituellen Ikterus de Neugeborenen.

Münch. med. Wschr., 55, 2169-74, 2233-37, 1908.

First detailed description of familial icterus gravis neonatorum.



Subjects: GENETICS / HEREDITY › HEREDITARY / CONGENITAL DISEASES OR DISORDERS › Icterus Gravis Neonatorum, HEMATOLOGY › Blood Disorders, PEDIATRICS › Neonatology
  • 3081

Haemophilia.

London: Dulau & Co, 1911.

Bulloch and Fildes, in their detailed account of hemophilia, claimed to have established immunity to the disease in females, and denied the authenticity of published cases of female hemophilia. They confirmed the law of Nasse. This work was issued as Memoir XII of the Eugenics Laboratory, University of London, and forms parts V-VI of the Treasury of Human Inheritance series.



Subjects: GENETICS / HEREDITY › HEREDITARY / CONGENITAL DISEASES OR DISORDERS › Blood Disorders › Hemophilia, HEMATOLOGY › Blood Disorders
  • 3082

Grundriss der hämatologischen Diagnostik.

Leipzig: W. Klinkhardt, 1911.

One of the leaders in modern hematology, Pappenheim improved the methods of staining blood cells.



Subjects: HEMATOLOGY
  • 3082.1

Ueber eine neue Leukämie durch echte Uebergangsformen (Splenozytenleukämie) und ihre Bedeutung für die Selbständigkeit dieser Zellen.

Münch. med. Wschr., 60, 1981-84, 1913.

Monocytic leukemia reported.



Subjects: HEMATOLOGY › Blood Disorders, ONCOLOGY & CANCER › Leukemia
  • 3083

Die essentielle Thrombopenie (konstitutionelle Purpura-Pseudo-Hämophilie).

Berl. klin. Wschr., 52, 454-58, 490-94, 1915.

Frank’s essential thrombopenia.



Subjects: HEMATOLOGY › Blood Disorders
  • 3084

Zur Therapie der Polyzythämie.

Therap. Mh., 32, 322-26, 1918.

Phenylhydrazine hydrochloride first used in the treatment of polycythemia.



Subjects: HEMATOLOGY
  • 3085

Studies of the suspension stability of the blood in pulmonary tuberculosis.

Acta med. scand., 54, 247-82, 1921.

Westergren’s method of measuring the erythrocyte sedimentation rate.



Subjects: HEMATOLOGY, PULMONOLOGY › Lung Diseases › Pulmonary Tuberculosis
  • 3086

Gangräneszierende Prozesse und Defekt des Granulocytensystems.

Dtsch. med. Wschr., 48, 1495-96, 1922.

“Schultz’s syndrome” – first description of agranulocytic angina. Schultz reported four cases of necrotic ulcerative infection of the throat with complete or almost complete disappearance of polymorphonuclears. To describe the blood change he introduced the term “agranulocytosis”.



Subjects: HEMATOLOGY › Blood Disorders
  • 3087

Die Sternumtrepanation, ein einfache Methode zur diagnostischen Entnahme von Knochenmark bei Lebenden.

Dtsch. med. Wschr., 49, 180-81, 1923.

Bone marrow biopsy by sternal puncture.



Subjects: HEMATOLOGY › Blood Disorders
  • 3087.1

Familial icterus gravis of the new-born and its treatment.

Canad. med. Ass. J., 15, 1008-112, 1925.

Successful exchange transfusion.



Subjects: GENETICS / HEREDITY › HEREDITARY / CONGENITAL DISEASES OR DISORDERS › Blood Disorders, HEMATOLOGY › Blood Disorders, THERAPEUTICS › Blood Transfusion
  • 3087.2

Hereditär pseudohemofili.

Fin. Läk.-Sallsk. Handl., 68, 87-112, 1926.

Von Willebrand’s disease, pseudo-hemophilia type B, an hereditary bleeding disorder affecting both sexes.



Subjects: GENETICS / HEREDITY › HEREDITARY / CONGENITAL DISEASES OR DISORDERS › Blood Disorders › Von Willebrand Disease, HEMATOLOGY › Blood Disorders
  • 3088

"Methodology of examining bone marrow in live patients, with haemopoietic disease."

Vestn. Khir., No. 30, 57-60, 1927.

Needle puncture of bone marrow biopsy. (In Russian.) German account in Folia haemat. (Lpz.), 1929, 38, 233-40. English translation from the German in Bick, Classics of orthopaedics, 339-44.



Subjects: COUNTRIES, CONTINENTS AND REGIONS › Russia, HEMATOLOGY › Blood Disorders, ONCOLOGY & CANCER, ORTHOPEDICS › Diseases of or Injuries to Bones, Joints & Skeleton
  • 3089

Demonstratie van een paar zeldzaam voorkomende typen van bloedlichaampjes en bespreking der patiënten.

Ned. T. Geneesk., 72, 1178, 1928.

See No. 3092.



Subjects: HEMATOLOGY › Blood Disorders
  • 3090

The velocity of blood flow in health and disease as measured by the effect of histamine on the minute vessels.

Amer. Heart J., 4, 664-91, 1929.

Measurement of circulation time.



Subjects: CARDIOLOGY, HEMATOLOGY › Blood Disorders
  • 3091

Eine klinisch brauchbare Bestimmungsmethode der Blutumlaufszeit mittels Decholininjektion.

Med. Klin., 27, 986-88, 1931.

The decholin method for estimation of circulation time. With J. Deutsch and Z. Brull.



Subjects: CARDIOLOGY
  • 3092

Over een familiaire anomalie der leucocyten.

Ned. T. Geneesk., 75, 5956-59, 1931.

Pelger–Huët anomaly of the nuclei of the leucocytes; see also No. 3089. German translation in Klin. Wschr., 1932, 11,1264-66.



Subjects: HEMATOLOGY › Blood Disorders
  • 3093

The haemostatic possibilities of snake-venom.

Lancet, 2, 985-87, 1934.

Snake venom used in the treatment of hemophilia.



Subjects: GENETICS / HEREDITY › HEREDITARY / CONGENITAL DISEASES OR DISORDERS › Blood Disorders › Hemophilia, HEMATOLOGY › Blood Disorders, TOXICOLOGY › Venoms
  • 3094

Sternal puncture; preliminary note.

J. Egypt, med Ass., 17, 846-50, 1934.

Needle for sternal puncture.



Subjects: COUNTRIES, CONTINENTS AND REGIONS › Egypt, HEMATOLOGY › Blood Disorders
  • 3095

The prothrombin in hemophilia and in obstructive jaundice.

J. biol. Chem., 109, lxxiii-lxxix, 1935.

Quick’s method for determination of prothrombin clotting time. See also Amer. JmedSci.,1935, 190,501-11.



Subjects: GENETICS / HEREDITY › HEREDITARY / CONGENITAL DISEASES OR DISORDERS › Blood Disorders › Hemophilia, HEMATOLOGY › Coagulation
  • 3096

A standardized technique for the blood sedimentation test.

Amer. J. med. Sci., 189, 102-15, 1935.

Wintrobe’s method for the determination of the erythrocyte sedimentation rate.



Subjects: HEMATOLOGY, Laboratory Medicine › Blood Tests
  • 3096.1

Hemophilia. II. Some properties of a substance obtained from normal human plasma effective in accelerating the coagulation of hemophilic blood.

J. clin. Invest., 16, 113-24, 1937.

Antihemophilic globulin (factor VIII).



Subjects: GENETICS / HEREDITY › HEREDITARY / CONGENITAL DISEASES OR DISORDERS › Blood Disorders › Hemophilia, HEMATOLOGY › Blood Disorders, HEMATOLOGY › Coagulation
  • 3097

The use of vitamin K and bile in treatment of the haemorrhagic diathesis in cases of jaundice.

Proc. Mayo Clin., 13, 74-80, 1938.

Vitamin K used in the treatment of hemorrhagic disease.



Subjects: HEMATOLOGY › Blood Disorders
  • 3098

Studies on leukemia with the aid of radioactive phosphorus.

New int. Clin., n.s. 2, vol. 3, 33-58, 1939.

Therapeutic use of radioactive isotopes for the treatment of leukemia. John H. Lawrence was the brother of Ernest Orlando Lawrence, inventor of the cyclotron; John Lawrence also worked at the Lawrence Berkeley National Laboratory.  With K. G. Scott and L. W. Tuttle.



Subjects: HEMATOLOGY › Blood Disorders, Nuclear Medicine, ONCOLOGY & CANCER › Leukemia, Radiation Oncology
  • 3099

Nuclear physics and therapy: preliminary report on a new method for the treatment of leukemia and polycythemia.

Radiology, 35, 51-60, 1940.

Radio-phosphorus in treatment of leukemia.



Subjects: HEMATOLOGY › Blood Disorders, Nuclear Medicine, ONCOLOGY & CANCER › Leukemia, RADIOLOGY